Dr Martin Read PhD

Dr Martin Read

Institute of Metabolism and Systems Research
Research Fellow

Contact details

Address
Institute of Metabolism and Systems Research
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Martin Read is a Research Fellow working with Professor Chris McCabe and Professor Jayne Franklyn in the Institute of Metabolism and Systems Research.

Qualifications

  • PhD (Diabetes research) University of Birmingham 1996
  • BSc (First Class with Honours in Biochemistry) University of Birmingham 1991

Teaching

Teaching Programmes

  • MRes Molecular Medicine- Hormones and Genes
  • BMedSc3 Molecular Medicine
  • BMedSc2 Understanding Thyroid Function
  • MBChB Year 1 Poster SS

Other activities

Postdoc Representative, School of Clinical and Experimental Medicine, 2011-Present

GM reviewer, College GM Safety Committee, 2011-Present

Editorial Advisor, Therapy Journal, 2003-2011

Scientific Consultant, Hybrid Systems Ltd, Oxford 2001-2003

Current member of the following societies:

  • American Association for Cancer research (AACR)
  • The Endocrine Society
  • The British Endocrine Society

Publications

Recent publications

Article

Read, M, Brookes, K, Thornton, C, Fletcher, A, Nieto, H, Alshahrani, M, Khan, R, Borges de Souza, P, Zha, L, Webster, J, Alderwick, L, Campbell, M, Boelaert, K, Smith, V & McCabe, C 2021, 'Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter', Cell Chemical Biology, vol. 2021, pp. 1-23. https://doi.org/10.1016/j.chembiol.2021.07.016

Fletcher, A, Read, M, Thornton, C, Larner, D, Poole, V, Brookes, K, Nieto, H, Alshahrani, M, Thompson, R, Lavery, G, Landa, I, Fagin, JA, Campbell, MJ, Boelaert, K, Turnell, A, Smith, V & McCabe, C 2020, 'Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 and valosin-containing protein enhances radioiodine uptake', Cancer Research, vol. 80, no. 1, pp. 102–115. https://doi.org/10.1158/0008-5472.CAN-19-1957

Nazeer, R, Qashqari, F, Albalawi, A, Piberger, AL, Tilotta, M, Read, M, Hu, S, Davis, S, McCabe, C, Petermann, E & Turnell, A 2019, 'Adenovirus E1B 55-kilodalton protein targets SMARCAL1 for degradation during infection and modulates cellular DNA replication', Journal of virology, vol. 93, no. 13, e00402-19. https://doi.org/10.1128/JVI.00402-19

Thompson, RJ, Fletcher, A, Brookes, K, Nieto, H, Alshahrani, MM, Mueller, JW, Fine, NHF, Hodson, DJ, Boelaert, K, Read, ML, Smith, VE & McCabe, CJ 2019, 'Dimerization of the sodium/iodide symporter', Thyroid, vol. 29, no. 10, pp. 1485-1498. https://doi.org/10.1089/thy.2019.0034

Seed, RI, Taurozzi, AJ, Wilcock, DJ, Nappo, G, Erb, HHH, Read, ML, Gurney, M, Archer, LK, Ito, S, Rumsby, MG, Petrie, JL, Clayton, A, Maitland, NJ & Collins, AT 2019, 'The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy', Scientific Reports, vol. 9, 5120. https://doi.org/10.1038/s41598-019-41379-8

Alshahrani, M, Fletcher, A, Thornton, C, Brookes, K, Nieto, H, Thompson, R, Read, M, Boelaert, K, McCabe, C & Smith, V 2018, 'Biochemical analysis of radioiodine uptake enhancement in endocrine cancer', Endocrine Abstracts, vol. 59, OC2.4. https://doi.org/10.1530/endoabs.59.OC2.4

Abstract

Read, M, Brookes, K, Thornton, C, Nieto, H, Fletcher, A, Borges de Souza, P, Alshahrani, M, Zha, L, Webster, J, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2021, 'Abstract PO-006: Exploiting non-canonical pathways of NIS regulation to enhance radioiodide uptake and identify predictive markers of recurrence in thyroid cancer', Clinical Cancer Research, vol. 27, no. 8 Supplement, PO-006. https://doi.org/10.1158/1557-3265.RADSCI21-PO-006

Read, M, Brookes, K, Thornton, C, Nieto, H, Fletcher, A, Zha, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2021, 'Exploiting non-canonical pathways of NIS regulation to enhance radioiodide uptake and identify predictive markers of thyroid cancer recurrence', Nuclear Medicine Communications, vol. 42, no. 5. https://doi.org/10.1097/MNM.0000000000001180

Read, M, Brookes, K, Thornton, C, Nieto, H, Fletcher, A, Zha, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2021, 'Targeting non-canonical pathways as a strategy to modulate radioiodide uptake in thyroid cancer', 27TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH, 9/06/21 - 12/06/21.

Read, M, Brookes, K, Fletcher, A, Thornton, C, Alshahrani, M, Khan, R, Nieto, H, Adcock, H, Webster, J, Cox, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2020, 'Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer', Journal of the Endocrine Society, vol. 4, no. Issue Supplement 1, OR28-03. https://doi.org/10.1210/jendso/bvaa046.2135

Read, M, Brookes, K, Fletcher, A, Thornton, C, Alshahrani, M, Khan, R, Nieto, H, Adcock, H, Webster, J, Cox, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2020, 'Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer', Endocrine Abstracts, vol. 70, OC5.4. https://doi.org/10.1530/endoabs.70.OC5.4

Read, M, Brookes, K, Fletcher, A, Thornton, C, Alshahrani, M, Nieto, H, Khan, R, Webster, J, Haggie, P, Verkman, A, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2019, 'A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy', Endocrine Abstracts, vol. 65, OC4.1. https://doi.org/10.1530/endoabs.65.OC4.1

Fletcher, A, Thompson, R, Read, M, Turnell, A, Smith, V & McCabe, C 2018, 'Abstract LB-327: Identification of novel sodium iodide symporter (NIS) interactors which modulate iodide uptake', Cancer Research, vol. 78, no. 13 Supplement, pp. LB327-LB327. https://doi.org/10.1158/1538-7445.AM2018-LB-327

Other contribution

Read, ML, Brookes, K, Thornton, CEM, Fletcher, A, Alshahrani, M, Khan, R, Nieto, HR, Souza, PBD, Webster, JRM, Alderwick, LJ, Boelaert, K, Smith, VE & McCabe, CJ 2020, New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer.. https://doi.org/10.1101/2020.07.21.213967

Preprint

Read, M, Brookes, K, Thornton, C, Fletcher, A, Nieto, H, Alshahrani, M, Khan, R, Borges de Souza, P, Zha, L, Webster, J, Alderwick, L, Campbell, M, Boelaert, K, Smith, V & McCabe, C 2021 'Targeting non-canonical pathways as a strategy to modulate the NIS symporter' SSRN. https://doi.org/10.2139/ssrn.3797274

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