Dr Martin Read PhD

Dr Martin Read

Institute of Metabolism and Systems Research
Research Fellow

Contact details

Address
Institute of Metabolism and Systems Research
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Martin Read is a Research Fellow working with Professor Chris McCabe and Professor Jayne Franklyn in the Institute of Metabolism and Systems Research.

Qualifications

  • PhD (Diabetes research) University of Birmingham 1996
  • BSc (First Class with Honours in Biochemistry) University of Birmingham 1991

Teaching

Teaching Programmes

  • MRes Molecular Medicine- Hormones and Genes
  • BMedSc3 Molecular Medicine
  • BMedSc2 Understanding Thyroid Function
  • MBChB Year 1 Poster SS

Other activities

Postdoc Representative, School of Clinical and Experimental Medicine, 2011-Present

GM reviewer, College GM Safety Committee, 2011-Present

Editorial Advisor, Therapy Journal, 2003-2011

Scientific Consultant, Hybrid Systems Ltd, Oxford 2001-2003

Current member of the following societies:

  • American Association for Cancer research (AACR)
  • The Endocrine Society
  • The British Endocrine Society

Publications

Recent publications

Article

Read, M, Brookes, K, Zha, L, Manivannan, S, Kim, J, Kocbiyik, M, Fletcher, A, Gorvin, CM, Firth, G, Fruhwirth, G, Nicola, J, Jhiang, S, Ringel, M, Campbell, M, Sunassee, K, Blower, P, Boelaert, K, Nieto, H, Smith, V & McCabe, C 2023, 'Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo', Clinical Cancer Research. https://doi.org/10.1158/1078-0432.CCR-23-2043

Abstract

Brookes, K, Read, M, Wani, S, Jhiang, S, Stover, D, Ringel, M, McCabe, C & Campbell, M 2024, 'Epigenetic approaches to deliver a targeted radiotherapy for triple negative breast cancer', Cancer Research, vol. 84, no. 9_Supplement, PO3-26-07. https://doi.org/10.1158/1538-7445.SABCS23-PO3-26-07

Fear, J, Desanti, GE, Brookes, K, Richardson, N, Thornton, CEM, Zha, L, Smith, VE, Read, ML, Dias, RP & McCabe, CJ 2024, 'Isolating human C cells by FACS for downstream -omics analysis to better understand the development of MTC in MEN2 patients', Thyroid Research, vol. 17, no. S1, PO1. https://doi.org/10.1186/s13044-024-00203-w

Manivannan, S, Kocbiyik, M, Banga, D, Afzal, A, Zha, L, Brookes, K, Nieto, HR, Thomas, S, Read, ML, McCabe, CJ & Smith, VE 2024, 'Proto-oncogene PBF regulation of cell adhesion and motility', Thyroid Research, vol. 17, no. S1, PO3. https://doi.org/10.1186/s13044-024-00203-w

Brookes, K, Zha, L, Kim, J, Wongsanit, S, Fear, J, Small, B, Nieto, HR, Kannappan, V, Wang, W, Jhiang, S, Ringel, MD, Campbell, MJ, Sunassee, K, Blower, PJ, Boelaert, K, Smith, VE, Read, ML & McCabe, CJ 2024, 'Transcriptional reprogramming using a new dual NIS agonist enhances radioiodide uptake with implications for predicting thyroid cancer recurrence', Thyroid Research, vol. 17, no. S1, OR2. https://doi.org/10.1186/s13044-024-00203-w

Brookes, K, Zha, L, Small, B, Kim, J, Manivannan, S, Thornton, C, Kannappan, V, Wang, W, Nieto, H, Sunassee, K, Blower, P, Smith, V, Read, M & McCabe, C 2023, 'A copper-based metabolite of disulfiram upregulates sodium iodide symporter (NIS) gene expression to enhance thyroidal uptake of radionuclides in vivo', Endocrine Abstracts, vol. 94, OC7.1. https://doi.org/10.1530/endoabs.94.OC7.1

Brookes, K, Zha, L, Kim, J, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Smith, V, Read, M & McCabe, C 2023, 'A critical role for copper in enhanced radioiodide uptake in thyroid cancer cells', Cancer Research, vol. 83, no. 7_Supplement, 5053. https://doi.org/10.1158/1538-7445.AM2023-5053

Manivannan, S, Banga, D, Kocbiyik, M, Read, M, Zha, L, Brookes, K, Nieto, H, McCabe, C & Smith, V 2023, 'A critical role for the proto-oncogene PBF in regulating cellular adhesion and motility in thyroid cancer', Endocrine Abstracts, vol. 94, OC2.6. https://doi.org/10.1530/endoabs.94.OC2.6

Brookes, K, Zha, L, Kim, J, Small, B, Kocbiyik, M, Manivannan, S, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Nieto, H, Smith, V, Read, M & McCabe, C 2023, 'Copper-based therapeutics increase sodium/iodide symporter (NIS) transcription and enhance radioiodide uptake in thyroid cancer cells', Endocrine Abstracts, vol. 90, OC11.1. https://doi.org/10.1530/endoabs.90.OC11.1

Manivannan, S, Kocbiyik, M, Alshahrani, M, El-Asrag, ME, Zha, L, Brookes, K, Nieto, H, Read, M, Beggs, A, McCabe, C & Smith, V 2023, 'Elucidating the mechanisms via which the proto-oncogene PBF stimulates cell motility in thyroid tumour progression', Thyroid Research, vol. 16, no. S1, PO2, pp. 6-6. https://doi.org/10.1186/s13044-023-00170-8

Manivannan, S, Kocbiyik, M, Alshahrani, M, EI-Asrag, M, Zha, L, Brookes, K, Nieto, H, Read, M, Beggs, A, McCabe, C & Smith, V 2023, 'Elucidating the mechanisms via which the proto-oncogene Pbf stimulates cell motility in thyroid tumor progression', Thyroid, vol. 33, no. S1, Poster 338, pp. A62-A62. https://doi.org/10.1089/thy.2023.29156.abstracts

Brookes, K, Zha, L, Kim, J, Kocbiyik, M, Manivannan, S, Sunassee, K, Blower, P, Nieto, H, Smith, V, Read, M & McCabe, C 2023, 'Exploiting endocytic factors as druggable targets to enhance sodium iodide symporter activity with clinical implications for radioiodide therapy', Thyroid Research, vol. 16, no. Supplement 1, OR4, pp. 4-4. https://doi.org/10.1186/s13044-023-00170-8

Brookes, K, Zha, L, Kim, J, Kocbiyik, M, Manivannan, S, Sunassee, K, Blower, P, Nieto, H, Smith, V, Read, M & McCabe, C 2023, 'Exploiting endocytic factors as druggable targets to enhance sodium iodide symporter activity with clinical implications for radioiodide therapy', Thyroid, vol. 33, no. S1, Poster 273, pp. A33-A34. https://doi.org/10.1089/thy.2023.29156.abstracts

Read, M, Brookes, K, Zha, L, Manivannan, S, Kim, J, Firth, G, Sunassee, K, Blower, P, Boelaert, K, Nieto, H, Smith, V & McCabe, C 2023, 'Manipulating NIS endocytosis as a druggable target to enhance radioiodide uptake and prognostic indictor of thyroid cancer recurrence', Endocrine Abstracts, vol. 94, OC2.1. https://doi.org/10.1530/endoabs.94.OC2.1

Preprint

Read, M, Brookes, K, Zha, L, Manivannan, S, Kim, J, Kocbiyik, M, Fletcher, A, Gorvin, CM, Firth, G, Fruhwirth, G, Nicola, J, Jhiang, S, Ringel, M, Campbell, M, Sunassee, K, Blower, P, Boelaert, K, Nieto, H, Smith, V & McCabe, C 2023 'Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy' bioRxiv. https://doi.org/10.1101/2023.05.22.541733

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