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Paiva, TO, Geoghegan, JA & Dufrêne, YF 2023, 'High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion', Communications Biology, vol. 6, no. 1, 302. https://doi.org/10.1038/s42003-023-04660-1
Paiva, TO, Viljoen, A, da Costa, TM, Geoghegan, JA & Dufrêne, YF 2023, 'Interaction of the Staphylococcus aureus surface protein FnBPB with corneodesmosin involves two distinct, extremely strong bonds', ACS nanoscience Au, vol. 3, no. 1, pp. 58-66. https://doi.org/10.1021/acsnanoscienceau.2c00036
Muñoz-Wolf, N, Ward, RW, Hearnden, CH, Sharp, FA, Geoghegan, J, O'Grady, K, McEntee, CP, Shanahan, KA, Guy, C, Bowie, AG, Campbell, M, Roces, CB, Anderluzzi, G, Webb, C, Perrie, Y, Creagh, E & Lavelle, EC 2023, 'Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles', Cell Reports Medicine, vol. 4, no. 1, 100899. https://doi.org/10.1016/j.xcrm.2022.100899
Clark, LC, Atkin, KE, Whelan, F, Brentnall, AS, Harris, G, Towell, AM, Turkenburg, JP, Liu, Y, Feizi, T, Griffiths, SC, Geoghegan, JA & Potts, JR 2023, 'Staphylococcal Periscope Proteins Aap, SasG and Pls project non-canonical legume-like lectin adhesin domains from the bacterial surface', The Journal of biological chemistry, vol. 299, no. 3, 102936. https://doi.org/10.1016/j.jbc.2023.102936
Henderson, SR & Geoghegan, JA 2023, 'The A domain of clonal complex 1-type fibronectin binding protein B promotes adherence and biofilm formation in Staphylococcus aureus', Microbiology, vol. 169, no. 6, 001348. https://doi.org/10.1099/mic.0.001348
Motta, C, Pellegrini, A, Camaione, S, Geoghegan, J, Speziale, P, Barbieri, G & Pietrocola, G 2023, 'von Willebrand factor-binding protein (vWbp)-activated factor XIII and transglutaminase 2 (TG2) promote cross-linking between FnBPA from Staphylococcus aureus and fibrinogen', Scientific Reports, vol. 13, no. 1. https://doi.org/10.1038/s41598-023-38972-3
Prencipe, F, Alsibaee, A, Khaddem, Z, Norton, P, Towell, AM, Ali, AFM, Reid, G, Fleury, OM, Foster, TJ, Geoghegan, JA, Rozas, I & Brennan, MP 2022, 'Allantodapsone is a Pan-Inhibitor of Staphylococcus aureus Adhesion to Fibrinogen, Loricrin, and Cytokeratin 10', Microbiology spectrum, vol. 10, no. 3, e0117521. https://doi.org/10.1128/spectrum.01175-21
da Costa, TM, Viljoen, A, Towell, AM, Dufrêne, YF & Geoghegan, JA 2022, 'Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus', Nature Communications, vol. 13, no. 1, 2517. https://doi.org/10.1038/s41467-022-30271-1
Martínez-Carmona, M, Cela, C, Kuznetsova, VA, Geoghegan, JA & Gun'ko, YK 2021, 'Enantioselective effect of cysteine functionalized mesoporous silica nanoparticles in U87 MG and GM08680 human cells and Staphylococcus aureus bacteria', Journal of Materials Chemistry B, vol. 9, no. 16, pp. 3544-3553. https://doi.org/10.1039/d0tb02532a
Towell, AM, Feuillie, C, Vitry, P, Da Costa, TM, Mathelié-Guinlet, M, Kezic, S, Fleury, OM, McAleer, MA, Dufrêne, YF, Irvine, AD & Geoghegan, JA 2021, 'Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 1, e2014444118. https://doi.org/10.1073/PNAS.2014444118
Saunders, SP, Floudas, A, Moran, T, Byrne, CM, Rooney, MD, Fahy, CMR, Geoghegan, JA, Iwakura, Y, Fallon, PG & Schwartz, C 2020, 'Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation', Allergy, vol. 75, no. 12, pp. 3216-3227. https://doi.org/10.1111/all.14488
Dorman, CJ & Geoghegan, J 2020, 'Editorial overview: Bacterial regulatory hierarchies and networks', Current Opinion in Microbiology, vol. 55, pp. iii-v. https://doi.org/10.1016/j.mib.2020.05.003
Olatunji, S, Yu, X, Bailey, J, Huang, C-Y, Zapotoczna, M, Bowen, K, Remškar, M, Müller, R, Scanlan, EM, Geoghegan, JA, Olieric, V & Caffrey, M 2020, 'Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin', Nature Communications, vol. 11, no. 1, 140. https://doi.org/10.1038/s41467-019-13724-y
Lacey, KA, Mulcahy, ME, Towell, AM, Geoghegan, JA & McLoughlin, RM 2019, 'Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target', PLoS pathogens, vol. 15, no. 4, pp. e1007713. https://doi.org/10.1371/journal.ppat.1007713
Pietrocola, G, Nobile, G, Alfeo, MJ, Foster, TJ, Geoghegan, JA, De Filippis, V & Speziale, P 2019, 'Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones', The Journal of biological chemistry, vol. 294, no. 10, pp. 3588-3602. https://doi.org/10.1074/jbc.RA118.005707
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