Professor Rachel Upthegrove MBBS, FRCPsych, PhD

School of Psychology
Professor of Psychiatry and Youth Mental Health
Consultant Psychiatrist Early Intervention in Psychosis

Contact details

Telephone: +44 (0)121 414 6241
Email: r.upthegrove@bham.ac.uk
Twitter: @RachelUTG

View my research portal

Address: School of Psychology
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Rachel is Professor of Psychiatry and Youth Mental Health at the University of Birmingham, and Consultant Psychiatrist in the Birmingham Early Intervention Services. Her research Interest is within the field of major mental illness; particularly schizophrenia and co-morbid depression in early phases of illness. Recent projects have developed the investigation of inflammatory models of psychosis and machine learning in prognostic indicators in early phases of developing mental ill health.

Qualifications

PhD Birmingham 2011
MPhil Birmingham 2001
FRCPsych 2017
MRCPsych 1999
MBBS University of London, Royal Free Hospital School of Medicine 1994

Teaching

Intercalated Degree Psychological Medicine Course Lead

Postgraduate supervision

Dr Upthegrove's primary research interests and background encompass the investigation of schizophrenia and psychosis, with particular emphasis on the importance of symptom dimensions and outcomes. She is happy to research doctoral projects on these themes.

Other activities

NIHR CRN Specialty Lead for the West Midlands

Council Member of the British Association for Psychopharmacology

Deputy Editor for the British Journal of Psychiatry

Publications

Recent publications

Article

Fisher, E, Wood, S, Upthegrove, R & Aldred, S 2020, 'Designing a feasible exercise intervention in first-episode psychosis: exercise quality, engagement and effect', Psychiatry Research, vol. 286, 112840. https://doi.org/10.1016/j.psychres.2020.112840

McGinty, J & Upthegrove, R 2020, 'Depressive symptoms during first episode psychosis and functional outcome: a systematic review and meta-analysis', Schizophrenia Research. https://doi.org/10.1016/j.schres.2019.12.011

Sampson, K, Upthegrove, R, Abu-Akel, A, Haque, S, Wood, S & Reniers, R 2020, 'Co-occurrence of autistic an psychotic traits: implications for depression, self-harm and suicidality', Psychological Medicine.

Jones, R, MacCabe, J, Liu, X, Price, M & Upthegrove, R 2020, 'Effect of age on the relative efficacy of clozapine in schizophrenia', Acta Psychiatrica Scandinavica.

Barnes, TR, Drake, R, Paton, C, Cooper, S, Deakin, JFW, Ferrier, N, Lewis, S, Joyce, EM, Upthegrove, R & Yung, A 2020, 'Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology', Journal of Psychopharmacology. https://doi.org/10.1177%2F1741143219888738

Chisholm, K, Pelton, M, Duncan, N, Kidd, K, Wardenaar, KJ, Upthegrove, R, Broome, M, Lin, A & Wood, S 2019, 'A cross-sectional examination of the clinical significance of autistic traits in individuals experiencing a first episode of psychosis', Psychiatry Research, vol. 282, 112623. https://doi.org/10.1016/j.psychres.2019.112623

Leighton, S, Upthegrove, R, Krishnadas, R, Benros, M, Broome, M, Gkoutos, G, Liddle, P, Singh, S, Everard, L, Jones, P, Fowler, D, Sharma, V, Freemantle, N, Christensen, R, Albert, N, Nordentoft, M, Schwannnauer, M, Cavanagh, J, Gumley, A, Birchwood, M & Mallikarjun, P 2019, 'Development and validation of multivariable prediction models of remission, recovery and quality of life outcomes in people with first episode psychosis: a machine learning approach', The Lancet Digital Health, vol. 1, no. 6, pp. e261-e270. https://doi.org/10.1016/S2589-7500(19)30121-9

Deakin, B, Suckling, J, Dazzan, P, Joyce, E, Lawrie, SM, Upthegrove, R, Husain, N, Chaudhry, IB, Dunn, G, Jones, PB, Lisiecka-ford, D, Lewis, S, Barnes, TR, Williams, SC, Pariante, CM, Knox, E, Drake, RJ, Smallman, R & Barnes, NM 2019, 'Minocycline for negative symptoms of schizophrenia and possible mechanistic actions: the BeneMin RCT', Efficacy and Mechanism Evaluation, vol. 6, no. 7, pp. 1-66. https://doi.org/10.3310/eme06070

Upthegrove, R & Khandaker, GM 2019, 'Cytokines, oxidative stress and cellular markers of inflammation in schizophrenia', Current Topics in Behavioral Neurosciences. https://doi.org/10.1007/7854_2018_88

Perry, BI, Khandaker, G, Marwaha, S, Zammit, S, Andrew, T, Singh, S & Upthegrove, R 2019, 'Insulin resistance and obesity, and their association with depression in relatively young people: findings from a large U.K. birth cohort', Psychological Medicine. https://doi.org/10.1017/ S0033291719000308

Qureshi, KL, Upthegrove, R, Toman, E, Sawlani, V, Davies, DJ & Belli, A 2019, 'Post-traumatic stress disorder in UK civilians with traumatic brain injury: an observational study of TBI clinic attendees to estimate PTSD prevalence and its relationship with radiological markers of brain injury severity', BMJ open, vol. 9, no. 2, e021675. https://doi.org/10.1136/bmjopen-2018-021675

Bown, D, Belli, A, Qureshi, K, Davies, D, Toman, E & Upthegrove, R 2019, 'Post-traumatic stress disorder and self-reported outcomes after traumatic brain injury in victims of assault', PLoS ONE, vol. 14, no. 2, e0211684. https://doi.org/10.1371/journal.pone.0211684