Highlight publications
PRONIA Consortium, Lalousis, PA, Schmaal, L, Wood, S, Reniers, R, Barnes, N, Chisholm, K, Griffiths, L, Stainton, A, Wen, J, Hwang, G, Davatzikos, C, Wenzel, J, Kambeitz-Ilankovic, L, Andreou, C, Bonivento, C, Dannlowski, U, Ferro, A, Liechtenstein, T, Riecher-Rössler, A, Romer, G, Rosen, M, Bertolino, A, Borgwardt, S, Brambilla, P, Kambeitz, J, Lencer, R, Pantelis, C, Ruhrmann, S, Salokangas, RKR, Schultze-Lutter, F, Schmidt, A, Meisenzahl, EM, Koutsouleris, N, Dwyer, D & Upthegrove, R 2022, 'Neurobiologically based stratification of recent-onset depression and psychosis: identification of two distinct transdiagnostic phenotypes', Biological Psychiatry, vol. 92, no. 7, pp. 552-562. https://doi.org/10.1016/j.biopsych.2022.03.021
Upthegrove, R, Marwaha, S & Birchwood, M 2017, 'Depression and schizophrenia: cause, consequence or trans-diagnostic issue?', Schizophrenia bulletin, vol. 43, no. 2, pp. 240-244. https://doi.org/10.1093/schbul/sbw097
PIMS collaboration 2022, 'Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: A Mendelian randomization study', JAMA psychiatry, vol. 2022, no. 5, pp. 1-11. https://doi.org/10.1001/jamapsychiatry.2022.0407
Morales-Munoz, I, Palmer, E, Mallikarjun, P, Marwaha, S & Upthegrove, R 2021, 'Persistent childhood and adolescent anxiety and risk for psychosis: a longitudinal birth cohort study', Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2021.12.003
PRONIA Consortium 2020, 'The psychopathology and neuroanatomical markers of depression in early psychosis', Schizophrenia bulletin, vol. 2020, sbaa094. https://doi.org/10.1093/schbul/sbaa094
Recent publications
Article
Griffiths, SL, Bogatsu, T, Longhi, M, Butler, E, Alexander, B, Bandawar, M, Everard, L, Jones, PB, Fowler, D, Hodgekins, J, Amos, T, Freemantle, N, McCrone, P, Singh, SP, Birchwood, M & Upthegrove, R 2023, 'Five-year illness trajectories across racial groups in the UK following a first episode psychosis', Social Psychiatry and Psychiatric Epidemiology. https://doi.org/10.1007/s00127-023-02428-w
Morales-Muñoz, I, Mallikarjun, PK, Chandan, JS, Thayakaran, R, Upthegrove, R & Marwaha, S 2023, 'Impact of anxiety and depression across childhood and adolescence on adverse outcomes in young adulthood: a UK birth cohort study', British Journal of Psychiatry , pp. 1-9. https://doi.org/10.1192/bjp.2023.23
Osimo, EF, Perry, BI, Mallikarjun, P, Prichard, M, Lewis, J, Katunda, A, Murray , GK, Perez, J, Jones, P, Cardinal, RN, Howes, OD, Upthegrove, R & Khandaker, G 2023, 'Predicting treatment resistance from first-episode psychosis using routinely collected clinical information', Nature Mental Health, vol. 1, pp. 25-35. https://doi.org/10.1038/s44220-022-00001-z
Morales-Muñoz, I, Upthegrove, R, Lawrence, K, Thayakaran, R, Kooij, S, Gregory, AM & Marwaha, S 2023, 'The role of inflammation in the prospective associations between early childhood sleep problems and ADHD at 10 years: findings from a UK birth cohort study', Journal of Child Psychology and Psychiatry. https://doi.org/10.1111/jcpp.13755
Shields, GE, Buck, D, Varese, F, Yung, AR, Thompson, A, Husain, N, Broome, MR, Upthegrove, R, Byrne, R & Davies, LM 2022, 'A review of economic evaluations of health care for people at risk of psychosis and for first-episode psychosis', BMC Psychiatry, vol. 22, no. 1, 126. https://doi.org/10.1186/s12888-022-03769-7
the PRONIA consortium 2022, 'Clinical, brain, and multilevel clustering in early psychosis and affective stages', JAMA psychiatry, vol. 79, no. 7, pp. 677-689. https://doi.org/10.1001/jamapsychiatry.2022.1163
Watson, AJ, Giordano, A, Suckling, J, Barnes, TRE, Husain, N, Jones, PB, Krynicki, CR, Lawrie, SM, Lewis, S, Nikkheslat, N, Pariante, CM, Upthegrove, R, Deakin, B, Dazzan, P & Joyce, EM 2022, 'Cognitive function in early-phase schizophrenia-spectrum disorder: IQ subtypes, brain volume and immune markers', Psychological Medicine. https://doi.org/10.1017/S0033291721004815
Rosen, M, Betz, LT, Kaiser, N, Penzel, N, Dwyer, D, Lichtenstein, TK, Schultze-Lutter, F, Kambeitz-Ilankovic, L, Bertolino, A, Borgwardt, S, Brambilla, P, Lencer, R, Meisenzahl, E, Pantelis, C, Salokangas, RKR, Upthegrove, R, Wood, S, Ruhrmann, S, Koutsouleris, N & Kambeitz, J 2022, 'Detailed clinical phenotyping and generalisability in prognostic models of functioning in at-risk populations', British Journal of Psychiatry, vol. 220, no. 6, pp. 318-321. https://doi.org/10.1192/bjp.2021.141
Jones, R, Upthegrove, R, Price, M, Pritchard, M, Chandan, J, Legge , S & MacCabe, J 2022, 'Duration of prior psychotic illness and clozapine response: a retrospective observational study using electronic health records', Therapeutic advances in psychopharmacology, vol. 12, pp. 1-12. https://doi.org/10.1177/20451253221103353
Perry, BI, Bowker, N, Burgess, S, Wareham, NJ, Upthegrove, R, Jones, P, Khandaker, GM & Langenberg, C 2022, 'Evidence for shared genetic aetiology between schizophrenia, cardiometabolic and inflammation related traits: genetic correlation and colocalization analyses', Schizophrenia Bulletin Open, vol. 3, no. 1, sgac001. https://doi.org/10.1093/schizbullopen/sgac001
Haas, SS, Doucet, GE, Antoniades, M, Modabbernia, A, Corcoran, CM, Kahn, RS, Kambeitz, J, Kambeitz-Ilankovic, L, Borgwardt, S, Brambilla, P, Upthegrove, R, Wood, SJ, Salokangas, RKR, Hietala, J, Meisenzahl, E, Koutsouleris, N & Frangou, S 2022, 'Evidence of discontinuity between psychosis-risk and non-clinical samples in the neuroanatomical correlates of social function', Schizophrenia Research: Cognition, vol. 29, 100252. https://doi.org/10.1016/j.scog.2022.100252
Koutsouleris, N, Pantelis, C, Velakoulis, D, Mcguire, P, Dwyer, DB, Urquijo-Castro, MF, Paul, R, Dong, S, Popovic, D, Oeztuerk, O, Kambeitz, J, Salokangas, RKR, Hietala, J, Bertolino, A, Brambilla, P, Upthegrove, R, Wood, SJ, Lencer, R, Borgwardt, S, Maj, C, Nöthen, M, Degenhardt, F, Polyakova, M, Mueller, K, Villringer, A, Danek, A, Fassbender, K, Fliessbach, K, Jahn, H, Kornhuber, J, Landwehrmeyer, B, Anderl-Straub, S, Prudlo, J, Synofzik, M, Wiltfang, J, Riedl, L, Diehl-Schmid, J, Otto, M, Meisenzahl, E, Falkai, P & Schroeter, ML 2022, 'Exploring links between psychosis and frontotemporal dementia using multimodal machine learning: Dementia Praecox revisited', JAMA psychiatry, vol. 79, no. 9, pp. 907-919. https://doi.org/10.1001/jamapsychiatry.2022.2075
Upthegrove, R 2022, 'From co-morbidity to transdiagnostic potential and novel immunotherapies for psychosis', Psychiatry Research, vol. 317, 114866. https://doi.org/10.1016/j.psychres.2022.114866
Review article
Griffiths, SL, Lalousis, PA, Wood, SJ & Upthegrove, R 2022, 'Heterogeneity in treatment outcomes and incomplete recovery in first episode psychosis: does one size fit all?', Translational Psychiatry, vol. 12, no. 1, 485. https://doi.org/10.1038/s41398-022-02256-7
Dunleavy, C, Elsworthy, RJ, Upthegrove, R, Wood, SJ & Aldred, S 2022, 'Inflammation in first-episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta-analysis', Acta Psychiatrica Scandinavica, vol. 146, no. 1, pp. 6-20. https://doi.org/10.1111/acps.13416
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