Recent publications
Article
Sampson, K, Upthegrove, R, Abu-Akel, A, Haque, S, Wood, S & Reniers, R 2020, 'Co-occurrence of autistic an psychotic traits: implications for depression, self-harm and suicidality', Psychological Medicine.
McGinty, J & Upthegrove, R 2020, 'Depressive symptoms during first episode psychosis and functional outcome: a systematic review and meta-analysis', Schizophrenia Research. https://doi.org/10.1016/j.schres.2019.12.011
Fisher, E, Wood, S, Upthegrove, R & Aldred, S 2020, 'Designing a feasible exercise intervention in first-episode psychosis: exercise quality, engagement and effect', Psychiatry Research, vol. 286, 112840. https://doi.org/10.1016/j.psychres.2020.112840
Jones, R, MacCabe, J, Liu, X, Price, M & Upthegrove, R 2020, 'Effect of age on the relative efficacy of clozapine in schizophrenia', Acta Psychiatrica Scandinavica. https://doi.org/10.1111/acps.13156
Salokangas, RKR, Hietala, J, Armio, RL, Laurikainen, H, From, T, Borgwardt, S, Riecher-Rössler, A, Brambilla, P, Bonivento, C, Meisenzahl, E, Schultze-Lutter, F, Haidl, T, Ruhrmann, S, Upthegrove, R, Wood, SJ, Pantelis, C, Kambeitz-Ilankovic, L, Ruef, A, Dwyer, DB, Kambeitz, J & Koutsouleris, N 2020, 'Effect of childhood physical abuse on social anxiety is mediated via reduced frontal lobe and amygdala-hippocampus complex volume in adult clinical high-risk subjects', Schizophrenia Research. https://doi.org/10.1016/j.schres.2020.05.041
Barnes, TR, Drake, R, Paton, C, Cooper, S, Deakin, JFW, Ferrier, N, Lewis, S, Joyce, EM, Upthegrove, R & Yung, A 2020, 'Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology', Journal of Psychopharmacology. https://doi.org/10.1177%2F1741143219888738
Aldred, S, Fisher, E, Upthegrove, R, Wood, S & Elsworthy, R 2020, 'Exercise as a protective mechanism against the negative effects of oxidative stress in first-episode psychosis: a biomarker led study.', Translational Psychiatry.
Heald, AH, Stedman, M, Davies, M, Farman, S, Upthegrove, R, Taylor, D & Gadsby, R 2020, 'Influences on the use of antidepressants in primary care: All England general practice-level analysis of demographic, practice-level and prescriber factors', Human Psychopharmacology. https://doi.org/10.1002/hup.2741
Upthegrove, R, Lalousis, PA, Mallikarjun, P, Chisholm, K, Griffiths, L, Iqbal, M, Pelton, M, Reniers, R, Stainton, A, Rosen, M, Ruef, A, Dwyer, D, Marian, S, Penzal, N, Kambietz, L, Alessasandro, B, Brambillo, P, Borgwardt, S, Kambietz, J, Lencer, R, Pantelis, C, Ruhrmann, S, Schultze Lutter, F, Salokangas, RKR, Meisenzahl, E, Wood, S & Koutsouleris, N 2020, 'The psychopathology and neuroanatomical markers of depression in early psychosis', Schizophrenia bulletin. https://doi.org/10.1093/schbul/sbaa094
David, P, Ruef, A, Chisholm, K, Wood, S, Upthegrove, R, Kambietz, L, Kambietz, J, Meisenzahl, E, Schultze Lutter, F, Brambillo, P, Borgwardt, S, Salokangas, RKR, Lencer, R, Ruhrmann, S & Koutsouleris, N 2020, 'Traces of trauma – a multivariate pattern analysis of childhood trauma, brain structure and clinical phenotypes', Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2020.05.020
Chisholm, K, Pelton, M, Duncan, N, Kidd, K, Wardenaar, KJ, Upthegrove, R, Broome, M, Lin, A & Wood, S 2019, 'A cross-sectional examination of the clinical significance of autistic traits in individuals experiencing a first episode of psychosis', Psychiatry Research, vol. 282, 112623. https://doi.org/10.1016/j.psychres.2019.112623
Upthegrove, R & Khandaker, GM 2019, 'Cytokines, oxidative stress and cellular markers of inflammation in schizophrenia', Current Topics in Behavioral Neurosciences. https://doi.org/10.1007/7854_2018_88
Leighton, S, Upthegrove, R, Krishnadas, R, Benros, M, Broome, M, Gkoutos, G, Liddle, P, Singh, S, Everard, L, Jones, P, Fowler, D, Sharma, V, Freemantle, N, Christensen, R, Albert, N, Nordentoft, M, Schwannnauer, M, Cavanagh, J, Gumley, A, Birchwood, M & Mallikarjun, P 2019, 'Development and validation of multivariable prediction models of remission, recovery and quality of life outcomes in people with first episode psychosis: a machine learning approach', The Lancet Digital Health, vol. 1, no. 6, pp. e261-e270. https://doi.org/10.1016/S2589-7500(19)30121-9
Comment/debate
Koutsouleris, N, Upthegrove, R & Wood, SJ 2019, 'Importance of variable selection in multimodal prediction models in patients at clinical high risk for psychosis and recent onset depression-reply', JAMA psychiatry, vol. 76, no. 3, pp. 339-340. https://doi.org/10.1001/jamapsychiatry.2018.4237
Review article
Grigoriou, M, Upthegrove, R & Bortolotti, L 2019, 'Instrumental rationality and suicide in schizophrenia: a case for rational suicide?', Journal of Medical Ethics, vol. 45, no. 12, pp. 802-805. https://doi.org/10.1136/medethics-2019-105454
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