Dr Mandy Maredza PhD

• PhD, Health Economics, University of Witwatersrand, South Africa, 2018
• Master of Public Health (Specialising in Health Economics), University of Cape Town, South Africa, 2009
• Bachelor of Pharmacy (Hons, Distinction), Rhodes University, South Africa, 2008

Dr Mandy Maredza is a health economist with over a decade of experience leading economic evaluations across clinical trials, public health interventions, and NICE technology appraisals. She joined the Birmingham Centre for Evidence and Implementation Science in 2025, following eight years at the University of Warwick—three years as a Senior Research Fellow with Warwick Evidence and five years as a Research Fellow within the Clinical Trials Unit.

Mandy has successfully led NICE appraisals, providing economic critique, evidence synthesis, and stakeholder engagement, and has represented evidence assessment groups at appraisal committee meetings. Her expertise spans trial-based evaluations and decision-analytic modelling, where she has designed and delivered health economic work packages, developed cost-effectiveness models, and contributed to high-impact publications, including in The Lancet and Health Technology Assessment.

Earlier in her career, she held roles with the Western Cape Department of Health and the Wits Centre for Health Economics and Decision Science in South Africa, where she worked closely with government and healthcare providers to evaluate interventions and inform resource allocation. She was awarded her PhD in 2018, which focused on potential cost-effective cardiovascular disease interventions in a marginalised community.

Looking ahead, Mandy is particularly interested in the role of artificial intelligence (AI) in health economics. With AI becoming increasingly important as both a medical device and analytic tool, she hopes to contribute to processes that ensure its meaningful and efficient integration into health economic analyses, helping to shape more equitable and evidence-driven healthcare systems.

Mandy is interested in supervising students in the following areas:

• Trial-based economic evaluations
• Decision- analytic modelling
• Health Technology Assessment

Dr Maredza’s research has consistently focused on generating economic evidence to inform health policy and practice, with work spanning oncology, orthopaedics, non-communicable diseases, HIV, and health system equity. Since 2021, her work has concentrated on health technology assessments (HTAs) in oncology, where she has led NICE reviews, provided economic critique of company submissions, and engaged with stakeholders to ensure analyses directly inform policy decisions.

Between 2016 and 2021, she specialised in trial-based economic evaluations, designing and implementing cost-effectiveness studies alongside large clinical trials, particularly in orthopaedic interventions and cancer drug evaluations. This body of work contributed to evidence used in funding applications, clinical guidelines, and publications in leading journals.

Her earlier research, based in South Africa, reflects a strong commitment to equity and priority setting in health systems. From 2014 to 2015, she investigated disparities in health service use and outcomes across the Western Cape Province, generating evidence that directly informed provincial health planning. Between 2010 and 2013, her work engaged policymakers to prioritise cost-effective interventions for non-communicable diseases, with models specifically tailored to the South African context.

Her first research projects explored HIV and infant feeding strategies, examining whether a 'one-size-fits-all' approach could meet the needs of both rural and urban communities. This work laid the foundation for her broader interest in ensuring that health economic evidence is context-specific, equitable, and policy-relevant.

Across these projects, Mandy’s research has bridged the gap between methodological rigour and real-world impact, consistently producing insights that support evidence-based, equitable, and cost-effective healthcare decision-making.