Dr Nathan Hodson PhD FHEA

Dr Nathan Hodson

School of Sport, Exercise and Rehabilitation Sciences
Assistant Professor in Exercise Physiology

Contact details

Address
School of Sport, Exercise and Rehabilitation Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dr Nathan Hodson is an exercise physiologist and biochemist primarily interested in the cellular mechanisms underpinning alterations in skeletal muscle size and protein metabolism across a range of populations; from athletes to older individuals or those living with muscle-wasting conditions.

Qualifications

PG Cert in Learning and Teaching in Higher Education, Manchester Metropolitan University, 2022
Fellow of the Higher Education Academy, 2022
PhD Exercise Biochemistry, University of Birmingham, 2018
MRes Exercise and Sport Science, University of Birmingham, 2015
BSc (Hons) Sport and Exercise Science, University of Birmingham, 2014

Biography

Dr Nathan Hodson completed his undergraduate and masters degrees within the School of Sport, Exercise and Rehabilitation Sciences at The University of Birmingham before continuing on to complete his PhD (2015-2018) within the School exploring the cellular mechanisms underpinning changes in skeletal muscle protein metabolism in response to exercise and nutrition. Following this, Dr. Hodson moved to Canada to complete post-doctoral training at the University of Toronto (2019-2021) furthering his expertise is methods to assess skeletal muscle protein metabolism through invasive and non-invasive methodologies.  Nathan then returned to the UK in December 2021 as a Lecturer in Musculoskeletal Physiology at Manchester Metropolitan University where he began his own research stream investigating skeletal muscle function and metabolism in a range of contexts; from athletic performance to muscle-wasting conditions. In September 2025, he rejoined the School of Sport, Exercise and Rehabilitation Sciences at the University of Birmingham where he continues his research into the cellular drivers of skeletal muscle protein metabolism alongside teaching on the School’s undergraduate and postgraduate programmes.

Throughout his career to date, Dr. Hodson’s work has been recognised with several awards including the Michael J Rennie Oral Communication Prize (Physiological Society, 2017), European College of Sport Science Young Investigator Award (2018) and American Society of Biochemistry and Molecular Biology Postdoctoral Award (2021). He has also presented his findings at a range of international conferences (ECSS, IBEC, Cell Symposia: Exercise Metabolism) and received funding from prestigious sources such as Muscular Dystrophy UK and The Academy of Medical Sciences.

Postgraduate supervision

Dr Hodson’s research group currently consists of 3 PhD students and 1 postdoctoral research associate:

  1. Ms. Meghann Leaver – PhD Student, 2023-2026
  2. Mr. Jordan Acheson – PhD Student, 2024-2027
  3. Ms. Isobel Haslam – PhD Student, 2024-2028
  4. Ms. Jennifer Barrett – PDRA, 2025-2027

If you are interested in working with Dr. Nathan Hodson and his group please contact n.w.hodson@bham.ac.uk to discuss potential opportunities and funding sources.

Research

Dr Hodson’s research focusses on the cellular mechanisms underpinning alterations in skeletal muscle protein metabolism and potential interventions to improve this in populations where it is impaired. He currently has the following ongoing projects/research themes: 

  • Investigating the role of the mTORC1-lysosomal-autophagy axis in obesity-related skeletal muscle anabolic resistance (Academy of Medical Sciences Springboard Award)
  • Investigating nutraceutical approaches to modulate skeletal muscle autophagy in response to exercise training and exercise-induced muscle damage (Industry partnership)
  • Understanding the relationship between dietary habits/supplementation and skeletal muscle size, strength and function in adults with muscular dystrophy
  • Utilising non-invasive approaches to study protein metabolism in adults with Becker Muscular Dystrophy (MDUK-funded PhD studentship)

Publications

Recent publications

Article

Horwath, O, Moberg, M, Hodson, N, Edman, S, Johansson, M, Andersson, E, van Hall, G, Rooyackers, O, Philp, A & Apró, W 2025, 'Anabolic sensitivity in healthy, lean, older men is associated with higher expression of amino acid sensors and mTORC1 activators compared to young', Journal of Cachexia, Sarcopenia and Muscle, vol. 16, no. 1, e13613. https://doi.org/10.1002/jcsm.13613

Hannon, SC, McStravick, J, Henthorn, L, Bawden, SJ, Tang, JCY, Dunn, R, Makino, R, Smith, K, Gonzalez, JT, Hodson, N, Morton, JP, Kennerley, AJ & Hearris, MA 2025, 'Co-ingesting whey protein with dual-source carbohydrate enhances amino acid availability without compromising post-exercise liver glycogen resynthesis', Journal of Physiology. https://doi.org/10.1113/JP288473

Fischer, A, Corr, L, Birdsey, LP, Hearris, M, Morgan, P, Hodson, N, Martinho, D, Fleming, J, Mohr, M, Krustrup, P, Russell, M, Sale, C, Harper, LD & Field, A 2025, 'Negligible Effects of Fructose–Glucose Composite Carbohydrates on Performance Across a Prolonged Soccer Match Simulation Compared With a Glucose-Only Control in Semiprofessional Soccer Players', International journal of sport nutrition and exercise metabolism, vol. 35, no. 3, pp. 404-415. https://doi.org/10.1123/IJSNEM.2024-0253

Bailleul, C, Hodson, N, Sawan, SA, Kumbhare, D, Moore, DR & Gillen, JB 2025, 'The influence of sex on fiber-specific indices of oxidative capacity in human skeletal muscle', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 329, no. 1, pp. R70-R80. https://doi.org/10.1152/ajpregu.00298.2024

Hannaian, SJ, Lov, J, Cheng-Boivin, Z, Sawan, SA, Hodson, N, Gentil, BJ, Morais, JA & Churchward-Venne, TA 2024, 'Acute effects of a ketone monoester, whey protein, or their coingestion on mTOR trafficking and protein-protein colocalization in human skeletal muscle', American Journal of Physiology - Cell Physiology, vol. 326, no. 6, pp. C1769-C1775. https://doi.org/10.1152/ajpcell.00207.2024

Purushotham, S, Hodson, N, Greig, C, Gardner, A & Falla, D 2024, 'Microscopic changes in the multifidus muscle in people with low back pain associated with lumbar disc herniation', Scientific Reports, vol. 14, no. 1, 31927. https://doi.org/10.1038/s41598-024-83373-9

Holowaty, MNH, Lees, MJ, Abou Sawan, S, Paulussen, KJM, Jäger, R, Purpura, M, Paluska, SA, Burd, NA, Hodson, N & Moore, DR 2023, 'Leucine ingestion promotes mTOR translocation to the periphery and enhances total and peripheral RPS6 phosphorylation in human skeletal muscle', Amino Acids, vol. 55, pp. 253-261. https://doi.org/10.1007/s00726-022-03221-w

Mazzulla, M, Hodson, N, West, DWD, Kumbhare, DA & Moore, DR 2022, 'A non-invasive 13CO2 breath test detects differences in anabolic sensitivity with feeding and heavy resistance exercise in healthy young males: a randomized control trial', Applied Physiology, Nutrition and Metabolism, vol. 47, no. 8, pp. 860-870. https://doi.org/10.1139/apnm-2021-0808

Lees, MJ, Hodson, N, Tinline-Goodfellow, CT, Fung, HJW, Elia, A & Moore, DR 2022, 'Challenges of rapamycin repurposing as a potential therapeutic candidate for COVID-19: implications for skeletal muscle metabolic health in older persons', American Journal of Physiology - Endocrinology and Metabolism, vol. 322, no. 6, pp. E551-E555. https://doi.org/10.1152/ajpendo.00064.2022

Waskiw-Ford, M, Hodson, N, Fung, HJW, West, DWD, Apong, P, Bashir, R & Moore, DR 2022, 'Essential Amino Acid Ingestion Facilitates Leucine Retention and Attenuates Myofibrillar Protein Breakdown following Bodyweight Resistance Exercise in Young Adults in a Home-Based Setting', Nutrients, vol. 14, no. 17, 3532. https://doi.org/10.3390/nu14173532

Cameron, A, Wakelin, G, Gaulton, N, Young, LV, Wotherspoon, S, Hodson, N, Lees, MJ, Moore, DR & Johnston, AP 2022, 'Identification of underexplored mesenchymal and vascular-related cell populations in human skeletal muscle', American journal of physiology. Cell physiology, vol. 323, no. 6, pp. C1586-C1600. https://doi.org/10.1152/ajpcell.00364.2022

Hodson, N, Mazzulla, M, Holowaty, MNH, Kumbhare, D & Moore, DR 2022, 'RPS6 phosphorylation occurs to a greater extent in the periphery of human skeletal muscle fibers, near focal adhesions, after anabolic stimuli', American Journal of Physiology - Cell Physiology, vol. 322, no. 1, pp. C94-C110. https://doi.org/10.1152/AJPCELL.00357.2021

Review article

Acheson, J, Joanisse, S, Sale, C & Hodson, N 2025, 'Recycle, repair, recover: the role of autophagy in modulating skeletal muscle repair and post-exercise recovery', Bioscience Reports, vol. 45, no. 1. https://doi.org/10.1042/BSR20240137

Talbot, C, Hodson, N, Rose, J & Bewley, S 2024, 'Comparing the psychological outcomes of donor and non-donor conceived people: A systematic review', BJOG: An International Journal of Obstetrics & Gynaecology, pp. 1-13. https://doi.org/10.1111/1471-0528.17892

Tinline-Goodfellow, CT, Lees, MJ & Hodson, N 2023, 'The skeletal muscle fiber periphery: A nexus of mTOR-related anabolism', Sports Medicine and Health Science, vol. 5, no. 1, pp. 10-19. https://doi.org/10.1016/j.smhs.2022.11.004

View all publications in research portal