Mr Samir Mehta

Mr Samir Mehta

Institute of Applied Health Research
Senior Medical Statistician

Contact details

Birmingham Clinical Trials Unit (BCTU)
University of Birmingham
B15 2TT

Samir Mehta has over 10 years’ experience in the design and analysis of clinical trials working as a Medical Statistician for the Birmingham Clinical Trials Unit (BCTU).

Samir's main portfolios within BCTU are trials related to Renal disease, surgical interventions and Atrial Fibrillation (AF).

Samir has also worked in trials related to Parkinson’s and cardiovascular disease, and is an experienced user of both major statistical analysis software packages SAS and STATA as required by MHRA for analysis of clinical trials.


  • MSc in Medical Statistics, University of Leicester, 2010
  • BSc (Hons) in Mathematics with Business Management, University Of Birmingham, 2009


Other activities

  • Statistical reviewer for the National Institute for Health Research (HTA, EME, RfPB)
  • Independent statistician on Trial Steering and Data Monitoring Committees contributing to the oversight and direction of externally run clinical trials


Recent publications


Bhandari, S, Mehta, S, Khawaja, A, Cleland, JGF, Rowland, N & Cockwell, P 2024, 'Evaluation of the stopping angiotensin converting enzyme inhibitor compared to angiotensin receptor blocker (STOP ACEi trial) in advanced and progressive chronic kidney disease', Kidney International, vol. 105, no. 1, pp. 200-208.

Smith, ME, Knappett, R, Vickers, D, White, D, Schramm, CJ, Mehta, S, Sun, Y, Watkins, B, Chadburn, M, Jarrett, H, James, K, Brettell, E, Roberts, TE, Bance, ML, Tysome, JR, INTEGRATE (the UK ENT Trainee Research Network) & Saniasiaya, J (ed.) 2024, 'Protocol for a multicentre randomised controlled trial of STeroid Administration Routes For Idiopathic Sudden sensorineural Hearing loss: The STARFISH trial', PLOS One, vol. 19, no. 2, e0290480.

Lasserson, D, Gaddu, P, Mehta, S, Ignatowicz, A, Greenfield, S, Prince, C, Cummins, C, Robinson, G, Rodrigues, J, Noble, S, Jowett, S, Toshner, M, Newnham, M & Turner, A 2024, 'Stopping anticoagulation for isolated or incidental pulmonary embolism: the STOPAPE RCT protocol', NIHR Journals Library.

ACTIVE Consortium, Schranz, P, Mandalia, V & O’brien, S 2023, 'A randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in patients with a failed primary treatment for chondral or osteochondral defects in the knee', American Journal of Sports Medicine, vol. 51, no. 2, pp. 367-378.

PREDNOS Collaborative Group, NIHR Medicines for Children Research Network Nephrology Clinical Studies Group, Afentou, N, Frew, E, Mehta, S, Rowland, N, Woolley, R, Brettell, E, Khan, A, Milford, D, Bockenhauer, D, Saleem , MA, Hall, AS, Koziell, A, Maxwell, H, Hegde , S, Finlay, ER, Gilbert, RD, Jones, C, McKeever, K, Cook, W, Webb, NJA & Christian, MT 2022, 'Economic evaluation of using daily prednisolone versus placebo at the time of an upper respiratory tract infection for the management of children with steroid-sensitive nephrotic syndrome: a model-based analysis', PharmacoEconomics, vol. 6, no. 4, pp. 605-617.

Jayne, D, Walsh, M, Merkel, PA, Peh, CA, Szpirt, W, Puéchal, X, Fujimoto, S, Hawley, C, Khalidi, N, Jones, R, Flossmann, O, Wald, R, Girard, L, Levin, A, Gregorini, G, Harper, L, Clark, W, Pagnoux, C, Specks, U, Smyth, L, Ito-Ihara, T, De zoysa, J, Brezina, B, Mazzetti, A, Mcalear, CA, Reidlinger, D, Mehta, S, Ives, N, Brettell, EA, Jarrett, H, Wheatley, K, Broadhurst, E, Casian, A & Pusey, CD 2022, 'Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT', Health Technology Assessment, vol. 26, no. 38, pp. 1-60.

STOP ACEi Trial Investigators 2022, 'Renin-angiotensin system inhibition in advanced chronic kidney disease', The New England Journal of Medicine.

Oesophago-Gastric Anastomotic Audit (OGAA) Collaborative 2022, 'Textbook outcome following oesophagectomy for cancer: international cohort study', British Journal of Surgery, vol. 109, no. 5, pp. 439-449.

The SUNRRISE Study Group on behalf of the Northwest Research Collaborative and the West Midlands Research Collaborative 2021, 'An international pragmatic randomised controlled trial to compare a single use negative pressure dressing versus a surgeon’s preference of dressing to reduce the incidence of surgical site infection following emergency laparotomy: the SUNRRISE Trial Protocol', Colorectal Disease, vol. 23, no. 4, pp. 989-1000.

Edwards, N, Price, A, Mehta, S, Hiemstra, TF, Kaur, A, Greasley , PJ, Webb, DJ, Dhaun, N, MacIntyre, IM, Farrah , T, Melville , V, Herrey , A, Slinn, G, Wale, B, Rowland, N, Wheeler, D, Wilkinson, I, Steeds, R, Ferro, C & Townend, J 2021, 'Effects of spironolactone and chlorthalidone on cardiovascular structure and function in chronic kidney disease', Clinical Journal of the American Society of Nephrology, vol. 16, no. 8, CJN.01930221.

Awasthi, A, Barbour, J, Beggs, A, Bhandari, P, Blakeway, D, Brookes, M, Brown, J, Brown, M, Caldwell, G, Clokie, S, Colleypriest, B, Conlin, A, Silva, SD, Caestecker, JD, Deeks, J, Dhar, A, Dilworth, M, Fogden, E, Foley, S, Ghosh, D, Grellier, L, Hart, A, Hoque, SS, Iacucci, M, Iqbal, T, James, J, Jarvis, M, Jayaprakash, A, Keshav, S, Magill, L, Matthews, G, Mawdsley, J, McLaughlin, S, Mehta, S, Monahan, K, Morton, D, Murugesan, S, Parkes, M, Pestinger, V, Probert, C, Ramadas, A, Rettino, A, Sebastian, S, Sharma, N, Griffiths, M, Stockton, J, Subramanian, V, Suggett, N, Taniere, P, Teare, J, Verma, AM & Wallis, Y 2021, 'Enhanced neoplasia detection in chronic ulcerative colitis: the ENDCaP-C diagnostic accuracy study', Efficacy and Mechanism Evaluation, vol. 8, no. 1, pp. 1-87.

Christian, M, Webb, NJA, Mehta, S, Woolley, R, Afentou, N, Frew, E, Brettell, E, Khan, A, Milford, D, Bockenhauer, D, Saleem , MA, Hall, AS, Koziell, A, Maxwell, H, Hegde , S, Prajapati , H, Gilbert, RD, Jones, C, McKeever, K, Cook, W & Rowland, N 2021, 'Evaluation of daily low-dose prednisolone during upper respiratory tract infection to prevent relapse in children with relapsing steroid-sensitive nephrotic syndrome: the PREDNOS 2 randomized clinical trial', JAMA Pediatrics.


Bhandari, S, Mehta, S, Ives, N & Cockwell, P 2024, 'WCN24-318: Utility of 2-year Kidney Failure Risk Equation for advanced chronic kidney disease: analysis from the STOP ACEi Trial', Kidney International Reports, vol. 9, no. 4, pp. S81-S82.

Spencer, S, Desborough, R, Mehta, S, Rowland, N & Bhandari, S 2024, 'WCN24-398: Report on STOP-ACEi trial: reviewing cystatin C levels in CKD patients', Kidney International Reports, vol. 9, no. 4, pp. S83-S83.


Bhandari, S, Mehta, S, Rowland, N & Cockwell, P 2023, 'Utility of 2-year kidney failure risk equation for advanced chronic kidney disease: analysis from the STOP-ACEi trial', Nephrology, Dialysis, Transplantation.

View all publications in research portal