Mr Samir Mehta

Mr Samir Mehta

Institute of Applied Health Research
Senior Medical Statistician

Contact details

Address
Birmingham Clinical Trials Unit (BCTU)
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Samir Mehta has over 10 years’ experience in the design and analysis of clinical trials working as a Medical Statistician for the Birmingham Clinical Trials Unit (BCTU).

Samir's main portfolios within BCTU are trials related to Renal disease, surgical interventions and Atrial Fibrillation (AF).

Samir has also worked in trials related to Parkinson’s and cardiovascular disease, and is an experienced user of both major statistical analysis software packages SAS and STATA as required by MHRA for analysis of clinical trials.

Qualifications

  • MSc in Medical Statistics, University of Leicester, 2010
  • BSc (Hons) in Mathematics with Business Management, University Of Birmingham, 2009

Teaching

Other activities

  • Statistical reviewer for the National Institute for Health Research (HTA, EME, RfPB)
  • Independent statistician on Trial Steering and Data Monitoring Committees contributing to the oversight and direction of externally run clinical trials

Publications

Recent publications

Article

Sterliński, M, Bunting, K, Boriani, G, Boveda, S, Guasch, E, Mont, L, Rajappan, K, Sommer, P, Mehta, S, Sun, Y, Gale, CP, van Deutekom, C, van Gelder, IC & Kotecha, D 2024, 'Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: A cluster-randomised trial by the European Society of Cardiology and European Heart Rhythm Association', EP Europace. https://doi.org/10.1093/europace/euae178

Bhandari, S, Mehta, S, Khawaja, A, Cleland, JGF, Rowland, N & Cockwell, P 2024, 'Evaluation of the stopping angiotensin converting enzyme inhibitor compared to angiotensin receptor blocker (STOP ACEi trial) in advanced and progressive chronic kidney disease', Kidney International, vol. 105, no. 1, pp. 200-208. https://doi.org/10.1016/j.kint.2023.09.012

Khan, N, Steeds, R, Kyte, D, Fabritz, L, Collis, P, Chua, WWL, Stubbs, C, Mehta, S, Sun, Y, Nulty, M, Kirkham, K & Cotton, JM 2024, 'Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK', BMJ open, vol. 14, no. 6, e086587. https://doi.org/10.1136/bmjopen-2024-086587

Data Analysis, Steering Committee, National Leads, Site Leads, Collaborators & Oesophago-Gastric Anastomotic Audit (OGAA) Collaborative 2024, 'Predictors of anastomotic leak and conduit necrosis after oesophagectomy: Results from the oesophago-gastric anastomosis audit (OGAA)', European Journal of Surgical Oncology, vol. 50, no. 6, 107983. https://doi.org/10.1016/j.ejso.2024.107983

Smith, ME, Knappett, R, Vickers, D, White, D, Schramm, CJ, Mehta, S, Sun, Y, Watkins, B, Chadburn, M, Jarrett, H, James, K, Brettell, E, Roberts, TE, Bance, ML, Tysome, JR, INTEGRATE (the UK ENT Trainee Research Network) & Saniasiaya, J (ed.) 2024, 'Protocol for a multicentre randomised controlled trial of STeroid Administration Routes For Idiopathic Sudden sensorineural Hearing loss: The STARFISH trial', PLOS One, vol. 19, no. 2, e0290480. https://doi.org/10.1371/journal.pone.0290480

Lasserson, D, Gaddu, P, Mehta, S, Ignatowicz, A, Greenfield, S, Prince, C, Cummins, C, Robinson, G, Rodrigues, J, Noble, S, Jowett, S, Toshner, M, Newnham, M & Turner, A 2024, 'Stopping anticoagulation for isolated or incidental pulmonary embolism: the STOPAPE RCT protocol', Health Technology Assessment. https://doi.org/10.3310/HRCW7937

ACTIVE Consortium, Schranz, P, Mandalia, V & O’brien, S 2023, 'A randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in patients with a failed primary treatment for chondral or osteochondral defects in the knee', American Journal of Sports Medicine, vol. 51, no. 2, pp. 367-378. https://doi.org/10.1177/03635465221141907

Steering Committee, C, Alderson, D, Bundred, J, Rpt, E, Gossage, J, Griffiths, EA, Jefferies, B, Kamarajah, SK, McKay, S, Mohamed, , Nepogodiev, D, Siaw- Acheampong, K, Singh, P, Van Hillegersberg, R, Vohra, R, Wanigasooriya, K, Whitehouse, T, National Leads, L, Gjata, A, Moreno, JI, Takeda, FR, Kidane, B, Guevara Castro, R, Harustiak, T, Bekele, A, Kechagias, A, Gockel, , Kennedy, A, Da Roit, A, Bagajevas, A, Azagra, JS, Mahendran, HA, Mejía-Fernández, L, Wijnhoven, BPL, El Kafsi, J, Sayyed, RH, Sousa, M, Sampaio, AS, Negoi, Blanco, R, Wallner, B, Schneider, PM, Hsu, PK, Isik, A, Leads, S, Gananadha, S, Wills, Devadas, M, Duong, C, Talbot, M, Hii, MW, Jacobs, R, Andreollo, NA, Johnston, B, Darling, G, Isaza-Restrepo, A, Rosero, G, Arias-Amézquita, F, Raptis, D, Gaedcke, J, Reim, D, Izbicki, J, Egberts, JH, Dikinis, S, Kjaer, DW, Larsen, MH, Achiam, MP, Saarnio, J, Theodorou, D, Liakakos, T, Korkolis, DP, Robb, WB, Collins, C, Murphy, T, Reynolds, J, Tonini, Migliore, M, Bonavina, L, Valmasoni, M, Bardini, R, Weindelmayer, J, Terashima, M, White, RE, Alghunaim, E, Elhadi, M, Leon-Takahashi, AM, Medina-Franco, H, Lau, PC, Okonta, KE, Heisterkamp, J, Rosman, C, Van Hillegersberg, R, Beban, G, Babor, R, Gordon, A, Rossaak, JI, Pal, KMI, Qureshi, AU, Naqi, SA, Syed, AA, Barbosa, J, Vicente, CS, Leite, J, Freire, J, Casaca, R, Costa, RCT, Scurtu, RR, Mogoanta, SS, Bolca, C, Constantinoiu, S, Sekhniaidze, D, Bjelović, M, So, JBY, Gačevski, G, Loureiro, C, Pera, M, Bianchi, A, Moreno Gijón, M, Martín Fernández, J, Trugeda Carrera, MS, Vallve-Bernal, M, Cítores Pascual, MA, Elmahi, S, Halldestam, Hedberg, J, Mönig, S, Gutknecht, S, Tez, M, Guner, A, Tirnaksiz, MB, Colak, E, Sevinç, B, Hindmarsh, A, Khan, Khoo, D, Byrom, R, Gokhale, J, Wilkerson, P, Jain, P, Chan, D, Robertson, K, Iftikhar, S, Skipworth, R, Forshaw, M, Higgs, S, Gossage, J, Nijjar, R, Viswanath, YKS, Turner, P, Dexter, S, Boddy, A, Allum, WH, Oglesby, S, Cheong, E, Beardsmore, D, Vohra, R, Maynard, N, Berrisford, R, Mercer, S, Puig, S, Melhado, R, Kelty, C, Underwood, T, Dawas, K, Lewis, W, Al-Bahrani, A, Bryce, G, Thomas, M, Arndt, AT, Palazzo, F, Meguid, RA, Collaborators, Fergusson, J, Beenen, E, Mosse, C, Salim, J, Cheah, S, Wright, T, Cerdeira, MP, McQuillan, P, Richardson, M, Liem, H, Spillane, J, Yacob, M, Albadawi, F, Thorpe, T, Dingle, A, Cabalag, C, Loi, K, Fisher, OM, Ward, S, Read, M, Johnson, M, Bassari, R, Bui, H, Cecconello, Raa, S, Da Rocha, JRM, Lopes, LR, Tercioti, V, Jds, C, Ferrer, JAP, Buduhan, G, Tan, L, Srinathan, S, Shea, P, Yeung, J, Allison, F, Carroll, P, Vargas-Barato, F, Gonzalez, F, Ortega, J, Nino-Torres, L, Beltrán-García, TC, Castilla, L, Pineda, M, Bastidas, A, Gómez-Mayorga, J, Cortés, N, Cetares, C, Caceres, S, Duarte, S, Pazdro, A, Snajdauf, M, Faltova, H, Sevcikova, M, Mortensen, PB, Katballe, N, Ingemann, T, Kruhlikava, MB, Ainswort, AP, Stilling, NM, Eckardt, J, Holm, J, Thorsteinsson, M, Siemsen, M, Brandt, B, Nega, B, Teferra, E, Tizazu, A, Kauppila, JH, Koivukangas, V, Meriläinen, S, Gruetzmann, R, Krautz, C, Weber, G, Golcher, H, Emons, G, Azizian, A, Ebeling, M, Niebisch, S, Kreuser, N, Albanese, G, Hesse, J, Volovnik, L, Boecher, U, Reeh, M, Triantafyllou, S, Schizas, D, Michalinos, A, Balli, E, Mpoura, M, Charalabopoulos, A, Manatakis, DK, Balalis, D, Bolger, J, Baban, C, Mastrosimone, A, McAnena, O, Quinn, A, Ó Súilleabháin, CB, Hennessy, MM, Ivanovski, Khizer, H, Ravi, N, Donlon, N, Cervellera, M, Vaccari, S, Bianchini, S, Sartarelli, L, Asti, E, Bernardi, D, Merigliano, S, Provenzano, L, Scarpa, M, Saadeh, L, Salmaso, B, De Manzoni, G, Giacopuzzi, S, La Mendola, R, De Pasqual, CA, Tsubosa, Y, Niihara, M, Irino, T, Makuuchi, R, Ishii, K, Mwachiro, M, Fekadu, A, Odera, A, Mwachiro, E, Alshehab, D, Ahmed, HA, Shebani, AO, Elhadi, A, Elnagar, FA, Elnagar, HF, Makkai-Popa, ST, Wong, LF, Tan, YR, Thannimalai, S, Ho, CA, Pang, WS, Tan, JH, Hnl, B, Cortés-González, R, Lagarde, SM, Van Lanschot, JJB, Cords, C, Jansen, WA, Martijnse, I, Matthijsen, R, Bouwense, S, Klarenbeek, B, Verstegen, M, Van Workum, F, Ruurda, JP, Van Der Sluis, PC, De Maat, M, Evenett, N, Johnston, P, Patel, R, MacCormick, A, Young, M, Smith, B, Ekwunife, C, Memon, AH, Shaikh, K, Wajid, A, Khalil, N, Haris, M, Mirza, ZU, Sba, Q, Sarwar, MZ, Shehzadi, A, Raza, A, Jhanzaib, MH, Farmanali, J, Zakir, Z, Shakeel, O, Nasir, Khattak, S, Baig, M, Noor, MA, Ahmed, HA, Naeem, A, Pinho, AC, Da Silva, R, Bernardes, A, Campos, JC, Matos, H, Braga, T, Monteiro, C, Ramos, P, Cabral, F, Gomes, MP, Martins, PC, Correia, AM, Videira, JF, Ciuce, C, Drasovean, R, Apostu, R, Ciuce, C, Paitici, S, Racu, AE, Obleaga, CV, Beuran, M, Stoica, B, Negoita, CC, Cordos, Birla, RD, Predescu, D, Hoara, PA, Tomsa, R, Shneider, Agasiev, M, Ganjara, Gunjić, D, Veselinović, M, Babič, T, Chin, TS, Shabbir, A, Kim, G, Crnjac, A, Samo, H, Díez Del Val, DV, Leturio, S, Ramón, JM, Dal Cero, M, Rifá, S, Rico, M, Pagan Pomar, A, Martinez Corcoles, JA, Rodicio Miravalles, JL, Pais, SA, Turienzo, SA, Alvarez, LS, Campos, PV, Rendo, AG, García, SS, Epg, S, Martínez, ET, Fernández Díaz, MJ, Magadán Álvarez, C, Martín, C, Díaz López, C, Rosat Rodrigo, A, Pérez Sánchez, LE, Bailón Cuadrado, M, Tinoco Carrasco, C, Choolani Bhojwani, E, Sánchez, DP, Ahmed, ME, Dzhendov, T, Lindberg, F, Rutegård, M, Sundbom, M, Mickael, C, Colucci, N, Schnider, A, Er, S, Kurnaz, E, Turkyilmaz, S, Turkyilmaz, A, Yildirim, R, Baki, BE, Akkapulu, N, Karahan, O, Damburaci, N, Hardwick, R, Safranek, P, Sujendran, , Bennett, J, Afzal, Z, Shrotri, M, Chan, B, Exarchou, K, Gilbert, T, Amalesh, T, Mukherjee, D, Mukherjee, S, Wiggins, TH, Kennedy, R, McCain, S, Harris, A, Dobson, G, Davies, N, Wilson, I, Mayo, D, Bennett, D, Young, R, Manby, P, Blencowe, N, Schiller, M, Byrne, B, Mitton, D, Wong, V, Elshaer, A, Cowen, M, Menon, Tan, L, McLaughlin, E, Koshy, R, Sharp, C, Brewer, H, Das, N, Cox, M, Al Khyatt, W, Worku, D, Iqbal, R, Walls, L, McGregor, R, Fullarton, G, MacDonald, A, MacKay, C, Craig, C, Dwerryhouse, S, Hornby, S, Jaunoo, S, Wadley, M, Baker, C, Saad, M, Kelly, M, Davies, A, Di Maggio, F, McKay, S, Mistry, P, Singhal, R, Tucker, O, Kapoulas, S, Powell-Brett, S, Davis, P, Bromley, G, Watson, L, Verma, R, Ward, J, Shetty, V, Ball, C, Pursnani, K, Sarela, A, Sue Ling, H, Mehta, S, Hayden, J, To, N, Palser, T, Hunter, D, Supramaniam, K, Butt, Z, Ahmed, A, Kumar, S, Chaudry, A, Moussa, O, Kordzadeh, A, Wilson, MLB, Patil, P, Noaman, Willem, J, Bouras, G, Evans, R, Singh, M, Warrilow, H, Ahmad, A, Tewari, N, Yanni, F, Couch, J, Theophilidou, E, Reilly, JJ, Singh, P, Van Boxel, G, Akbari, K, Zanotti, D, Sgromo, B, Sanders, G, Wheatley, T, Ariyarathenam, A, Reece-Smith, A, Humphreys, L, Choh, C, Carter, N, Knight, B, Pucher, P, Athanasiou, A, Mohamed, Tan, B, Abdulrahman, M, Vickers, J, Akhtar, K, Chaparala, R, Brown, R, Alasmar, MMA, Ackroyd, R, Patel, K, Tamhankar, A, Wyman, A, Walker, R, Grace, B, Abbassi, N, Slim, N, Ioannidi, L, Blackshaw, G, Havard, T, Escofet, X, Powell, A, Owera, A, Rashid, F, Jambulingam, P, Padickakudi, J, Ben-Younes, H, McCormack, K, Makey, IA, Karush, MK, Seder, CW, Liptay, MJ, Chmielewski, G, Rosato, EL, Berger, AC, Zheng, R, Okolo, E, Singh, A, Scott, CD, Weyant, MJ & Mitchell, JD 2023, 'Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma: An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA)', Annals of surgery, vol. 277, no. 5, pp. E1026-E1034. https://doi.org/10.1097/SLA.0000000000005394

PREDNOS Collaborative Group, NIHR Medicines for Children Research Network Nephrology Clinical Studies Group, Afentou, N, Frew, E, Mehta, S, Rowland, N, Woolley, R, Brettell, E, Khan, A, Milford, D, Bockenhauer, D, Saleem , MA, Hall, AS, Koziell, A, Maxwell, H, Hegde , S, Finlay, ER, Gilbert, RD, Jones, C, McKeever, K, Cook, W, Webb, NJA & Christian, MT 2022, 'Economic evaluation of using daily prednisolone versus placebo at the time of an upper respiratory tract infection for the management of children with steroid-sensitive nephrotic syndrome: a model-based analysis', PharmacoEconomics, vol. 6, no. 4, pp. 605-617. https://doi.org/10.1007/s41669-022-00334-6

Jayne, D, Walsh, M, Merkel, PA, Peh, CA, Szpirt, W, Puéchal, X, Fujimoto, S, Hawley, C, Khalidi, N, Jones, R, Flossmann, O, Wald, R, Girard, L, Levin, A, Gregorini, G, Harper, L, Clark, W, Pagnoux, C, Specks, U, Smyth, L, Ito-Ihara, T, De zoysa, J, Brezina, B, Mazzetti, A, Mcalear, CA, Reidlinger, D, Mehta, S, Ives, N, Brettell, EA, Jarrett, H, Wheatley, K, Broadhurst, E, Casian, A & Pusey, CD 2022, 'Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT', Health Technology Assessment, vol. 26, no. 38, pp. 1-60. https://doi.org/10.3310/PNXB5040

STOP ACEi Trial Investigators 2022, 'Renin-angiotensin system inhibition in advanced chronic kidney disease', The New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2210639

Oesophago-Gastric Anastomotic Audit (OGAA) Collaborative 2022, 'Textbook outcome following oesophagectomy for cancer: international cohort study', British Journal of Surgery, vol. 109, no. 5, pp. 439-449. https://doi.org/10.1093/bjs/znac016

Abstract

Bhandari, S, Mehta, S, Ives, N & Cockwell, P 2024, 'WCN24-318: Utility of 2-year Kidney Failure Risk Equation for advanced chronic kidney disease: analysis from the STOP ACEi Trial', Kidney International Reports, vol. 9, no. 4, pp. S81-S82. https://doi.org/10.1016/j.ekir.2024.02.174

Spencer, S, Desborough, R, Mehta, S, Rowland, N & Bhandari, S 2024, 'WCN24-398: Report on STOP-ACEi trial: reviewing cystatin C levels in CKD patients', Kidney International Reports, vol. 9, no. 4, pp. S83-S83. https://doi.org/10.1016/j.ekir.2024.02.176

Letter

Bhandari, S, Mehta, S, Rowland, N & Cockwell, P 2023, 'Utility of 2-year kidney failure risk equation for advanced chronic kidney disease: analysis from the STOP-ACEi trial', Nephrology, Dialysis, Transplantation. https://doi.org/10.1093/ndt/gfad263

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