Recent publications
Article
McPherson, A, Paudyal, V, Lowrie, R, Heath, H, Moir, J, Allen, N, Barnes, N, Hill, H, Araf, A, Lombard, C, Ross, S, Tearne, S, Jagpal, P, Middleton, L, Cheed, V, Hislop, J, Akhtar, S, Provan, G, Williamson, AE & Mair, FS 2025, 'Baseline characteristics of people experiencing homelessness in the PHOENIx community pharmacy multicentre pilot randomised controlled trial', International Journal for Equity in Health, vol. 24, 289. https://doi.org/10.1186/s12939-025-02627-8
Antoun, L, Woolley, R, Middleton, L, Smith, P, Saridogan, E, Cooper, KG, McKinnon, W, Bevan, S, Ziomek, K, Sairally, BZ, Jones, L, Fullard, J, Morgan, M & Clark, TJ 2025, 'Comparison of complications and recovery after laparoscopic and abdominal hysterectomy for benign disease: The LAparoscopic Versus Abdominal hysterectomy (LAVA) randomised controlled trial', BMJ open, vol. 15, e096265. https://doi.org/10.1136/bmjopen-2024-096265
Devall, AJ, Nausheen, S, Muhammad, S, Soofi, S, Karmaliani, R, Lakhani, A, Sajid, K, Ahmed, I, Raza, A, Ashraf, A, Shahid, N, Mubeen, K, Wahab, S, Liaquat, R, Evans, C, Martin, JT, Middleton, LJ, Beeson, LE, Sindhu, KN, Podesek, M, Horne, I, Aswat, A, Oladapo, OT, Gallos, ID, Hemming, K, Yunas, I, Sheikh, L & Coomarasamy, A 2025, 'Early Detection and Bundled Treatment of Postpartum Haemorrhage with the E-MOTIVE intervention: A Prospective Pre-Post Intervention Study in Pakistan', The Lancet Obstetrics, Gynaecology and Women's Health. https://doi.org/10.1016/j.lanogw.2025.100010
Matthews, L, Clark, J, Bevan, S, Middleton, L, Antoun, L, Smith, P, Saridogan, E, Woolley, R, Morgan, M & Jones, L 2025, 'Feasibility, acceptability and appropriateness of laparoscopic versus abdominal hysterectomy for women and healthcare professionals: the LAVA trial qualitative process evaluation', Health Technology Assessment, pp. 1-21. https://doi.org/10.3310/GJTC1325
Kenyon, S, Johnston, T, Waugh, J, Hinshaw, K, Sanders, J, Ewer, A, Middleton, L, Stubbs, C, Cheed, V, Summers, H, Hewston, R, Wilcockson, A, Siddall, K, Wherton, D & Brocklehurst, P 2025, 'High or low dose oxytocin for nulliparous women delayed in the first stage of labour: the HOLDS RCT', Health Technology Assessment. https://doi.org/10.3310/MALP6685
Lowrie, R, Paudyal, V, McPherson, A, Heath, H, Moir, J, Allen, N, Barnes, N, Hill, H, Araf, A, Lombard, C, Ross, S, Tearne, S, Jagpal, P, Cheed, V, Middleton, L, Akhtar, S, Provan, G, Hislop, J, Williamson, A & Mair, FS 2025, 'Pharmacy Homeless Outreach Engagement Non-medical Independent Prescribing Rx (PHOENIx) Community Pharmacy-Based Pilot Randomized Controlled Trial: PHOENIx: a community pharmacy-based pilot RCT for PEH', Journal of Urban Health, vol. 102, no. 3, pp. 540-563. https://doi.org/10.1007/s11524-025-00981-0
Williams, EV, Goranitis, I, Oppong, R, Perry, SJ, Devall, AJ, Martin, JT, Mammoliti, K-M, Beeson, LE, Sindhu, KN, Galadanci, H, Al-beity, FA, Qureshi, Z, Hofmeyr, GJ, Moran, N, Fawcus, S, Mandondo, S, Middleton, L, Hemming, K, Oladapo, OT, Gallos, ID, Coomarasamy, A & Roberts, TE 2024, 'A cost-effectiveness analysis of early detection and bundled treatment of postpartum haemorrhage alongside the E-MOTIVE trial', Nature Medicine. https://doi.org/10.1038/s41591-024-03069-5
Hodgetts Morton, V, Moakes, CA, Daniels, J, Middleton, L, Shennan, A, Brocklehurst, P, Israfil-Bayli, F, Ewer, AK, Simpson, NA, Norman, JE, Lees, C, Tryposkiadis, K, Stubbs, C, Hughes, M, Morris, RK, Toozs-Hobson, P & Gray, J 2024, 'Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT', Health Technology Assessment, vol. 28, no. 40, pp. 1-44. https://doi.org/10.3310/YKTW8402
Cooper, KG, Bhattacharya, S, Daniels, JP, Horne, AW, Clark, TJ, Saridogan, E, Cheed, V, Pirie, D, Melyda, M, Monahan, M, Roberts, TE, Cox, E, Stubbs, C, Middleton, LJ & PRE-EMPT Collaborative Group 2024, 'Long acting progestogens versus combined oral contraceptive pill for preventing recurrence of endometriosis related pain: the PRE-EMPT pragmatic, parallel group, open label, randomised controlled trial', BMJ open, vol. 385, e079006. https://doi.org/10.1136/bmj-2023-079006
ACTIVE Consortium, Schranz, P, Mandalia, V & O’brien, S 2023, 'A randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in patients with a failed primary treatment for chondral or osteochondral defects in the knee', American Journal of Sports Medicine, vol. 51, no. 2, pp. 367-378. https://doi.org/10.1177/03635465221141907
GEM3 Collaborative Group 2023, 'Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial', The Lancet. https://doi.org/10.1016/S0140-6736(22)02478-3
GEM3 Collaborative Group 2023, 'Gefitinib and methotrexate to resolve tubal ectopic pregnancy: the GEM3 RCT', Efficacy and Mechanism Evaluation, vol. 10, no. 1. https://doi.org/0.3310/NNZF1037
Antoun, L, Middleton, L, Smith, P, Saridogan, E, Cooper, K, Brocklehurst, P, McKinnon, W, Bevan, S, Woolley, R, Jones, L, Fullard, J, Morgan, M, Roberts, T & Clark, TJ 2023, 'LAparoscopic Versus Abdominal hysterectomy (LAVA): protocol of a randomised controlled trial', BMJ open, vol. 13, no. 9, e070218. https://doi.org/10.1136/bmjopen-2022-070218
Martin, J, Middleton, L & Hemming, K 2023, 'Minimisation for the design of parallel cluster-randomised trials: An evaluation of balance in cluster-level covariates and numbers of clusters allocated to each arm', Clinical Trials, vol. 20, no. 2, pp. 111–120. https://doi.org/10.1177/17407745221149104
Review article
Thompson, J, Watson, SI, Middleton, L & Hemming, K 2025, 'Estimating relative risks and risk differences in randomised controlled trials: a systematic review of current practice', Trials, vol. 26, 1. https://doi.org/10.1186/s13063-024-08690-w
View all publications in research portal