Raoul Reulen PhD, MSc

Department of Applied Health Sciences
Honorary Associate Professor in Cancer Epidemiology

Contact details

Email: r.c.reulen@bham.ac.uk

View my research portal

Address: Department of Applied Health Sciences
School of Health Sciences
College of Medicine and Health
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Raoul Reulen is Associate Professor in Cancer Epidemiology at the Centre for Childhood Cancer Survivor Studies.

Qualifications

PhD Cancer Epidemiology, University of Birmingham, 2009
MSc Epidemiology, Maastricht University, 2005
MSc Health Sciences, Maastricht University, 2005

Biography

Raoul Reulen is a cancer epidemiologist with more than 20 years of academic experience specialising in the long-term health consequences of cancer treatment in childhood, adolescent and young adult survivors. He has expertise in large-scale observational real world evidence studies, registry linkage, and survival analysis methods. Author of 85+ peer-reviewed publications; h-index 40. Raoul’s research focuses on the long-term health consequences of cancer and its treatment, primarily in survivors of childhood (age 0–14) and young adulthood (age 15–39) cancer. His work uses large-scale population-based cohort studies linked to national health registries and administrative datasets to quantify risks of adverse outcomes decades after diagnosis.

His national research has centred on two cohort studies: the British Childhood Cancer Survivor Study (BCCSS), comprising nearly 35,000 five-year survivors of childhood cancer diagnosed between 1941 and 2006, and the Teenage and Young Adult Cancer Survivor Study (TYACSS), with over 200,000 survivors diagnosed between 1970 and 2006. Both cohorts have been linked to national death and cancer registrations, Hospital Episode Statistics (HES), national prescription databases, and Mental Health Services Dataset enabling investigation of late mortality, subsequent primary tumours, cardiovascular disease, pulmonary outcomes, mental health, and adverse pregnancy outcomes. His work has generated over 85 peer-reviewed publications in journals including JAMA, BMJ and Lancet Oncology. Internationally, Raoul has played a leading role in the EU-funded PanCareSurFup study, where he coordinated the pooling and analysis of data from 13 cohorts across 12 European countries to quantify the risks of subsequent primary neoplasms.

Postgraduate supervision

Dr Reulen is interested in supervising doctoral research on late physical effects in survivors of a cancer in childhood, teenage years or young adulthood.

Publications

Recent publications

Article

Aho Glele, R, Feijen, EAM, Fresneau, B, Reulen, RC, Allodji, RS, Vu-Bezin, G, Schwartz, B, Journy, N, Minard-Colin, V, Bagnasco, F, Bardi, E, Belle, FN, Byrne, J, van Dalen, EC, Teepen, JC, Grabow, D, Kaatsch, P, Hjorth, L, Jankovic, M, Kuehni, CE, Levitt, G, Veres, C, Aerts, I, Zadravec Zaletel, L, van der Pal, HJH, Ronckers, C, Sacerdote, C, Skinner, R, Jakab, Z, Michel, G, Terenziani, M, Haddy, N, Thierry-Chef, I, Cardis, E, Diallo, I, Winter, DL, Kremer, LCM, Hawkins, MM & de Vathaire, F 2025, 'Risk Factors for Valvulopathy Among Childhood Cancer Survivors', JAMA Oncology, vol. 11, no. 12, pp. 1449-1457. https://doi.org/10.1001/jamaoncol.2025.3863

Heymer, EJ, Jóźwiak, K, Kremer, LC, Winter, DL, de Vathaire, F, Sunguc, C, Sugden, E, Kok, JL, van der Pal, HJH, Hjorth, L, Jakab, Z, Maule, MM, Haupt, R, Bagnasco, F, Terenziani, M, Diallo, I, Gunnes, MW, Sommer, G, Zadravec Zaletel, L, Kuehni, CE, Winther, JF, Lähteenmäki, PM, Gudmundsdottir, T, Allodji, RS, Skinner, R, Ronckers, CM, Hawkins, MM, Reulen, RC & Teepen, JC 2024, 'Cumulative Absolute Risk of Subsequent Colorectal Cancer After Abdominopelvic Radiotherapy Among Childhood Cancer Survivors: A PanCareSurFup Study', Journal of Clinical Oncology , vol. 42, no. 3, pp. 336-347. https://doi.org/10.1200/JCO.23.00452

Diallo, I, Allodji, RS, Veres, C, Bolle, S, Llanas, D, Ezzouhri, S, Zrafi, W, Debiche, G, Souchard, V, Fauchery, R, Haddy, N, Journy, N, Demoor-Goldschmidt, C, Winter, DL, Hjorth, L, Wiebe, T, Haupt, R, Robert, C, Kremer, L, Bardi, E, Sacerdote, C, Terenziani, M, Kuehni, CE, Schindera, C, Skinner, R, Winther, JF, Lähteenmäki, P, Byrn, J, Jakab, Z, Cardis, E, Pasqual, E, Tapio, S, Baatout, S, Atkinson, M, Benotmane, MA, Sugden, E, Zaletel, LZ, Ronckers, C, Reulen, RC, Hawkins, MM & de Vathaire, F 2024, 'Radiation doses received by major organs at risk in children and young adolescents treated for cancer with external beam radiation therapy: a large-scale study from 12 European countries', International Journal of Radiation: Oncology - Biology - Physics . https://doi.org/10.1016/j.ijrobp.2024.03.032

Heymer, EJ, Hawkins, MM, Winter, DL, Teepen, JC, Sunguc, C, Ronckers, CM, Allodji, RS, Alessi, D, Sugden, E, Belle, FN, Bagnasco, F, Byrne, J, Bárdi, E, Garwicz, S, Grabow, D, Jankovic, M, Kaatsch, P, Kaiser, M, Michel, G, Schindera, C, Haddy, N, Journy, N, Česen Mazić, M, Skinner, R, Kok, JL, Gunnes, MW, Wiebe, T, Sacerdote, C, Maule, MM, Terenziani, M, Jakab, Z, Winther, JF, Lähteenmäki, PM, Zadravec Zaletel, L, Haupt, R, Kuehni, CE, Kremer, LC, de Vathaire, F, Hjorth, L & Reulen, RC 2024, 'Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study', British Journal of Cancer, vol. 130, no. 6, pp. 976-986. https://doi.org/10.1038/s41416-024-02577-y

Sunguc, C, Winter, DL, Heymer, EJ, Rudge, G, Polanco, A, Birchenall, KA, Griffin, M, Anderson, RA, Wallace, WHB, Hawkins, MM & Reulen, RC 2024, 'Risks of adverse obstetric outcomes among female survivors of adolescent and young adult cancer in England (TYACSS): a population-based, retrospective cohort study', The Lancet Oncology, vol. 25, no. 8, pp. 1080-1091. https://doi.org/10.1016/S1470-2045(24)00269-9

Reulen, RC, Winter, DL, Diallo, I, Veres, C, Llanas, D, Allodji, RS, Bagnasco, F, Bárdi, E, Feijen, EAM, Alessi, D, Fidler-Benaoudia, MM, Høgsholt, S, Teepen, JC, Linge, H, Haddy, N, Byrne, J, Debiche, G, Grabow, D, Gudmundsdottir, T, Fauchery, R, Zrafi, W, Michel, G, Øfstaas, H, Kaatsch, P, Vu-Bezin, G, Jenkinson, H, Kaiser, M, Skinner, R, Cole, T, Waespe, N, Sommer, G, Nordenfelt, S, Jankovic, M, Lähteenmäki Taalas, T, Maule, MM, van der Pal, HJH, Ronckers, CM, van Leeuwen, FE, Kok, JL, Terenziani, M, Winther Gunnes, M, Wiebe, T, Sacerdote, C, Jakab, Z, Haupt, R, Lähteenmäki, PM, Zadravec Zaletel, L, Kuehni, CE, Falck Winther, J, Kremer, LCM, Hjorth, L, de Vathaire, F & Hawkins, MM 2023, 'Risk Factors for Primary Bone Cancer After Childhood Cancer: A PanCare Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies Nested Case-Control Study', Journal of Clinical Oncology , vol. 41, pp. 3735-3746. https://doi.org/10.1200/JCO.22.02045

Dudley, IM, Sunguc, C, Winter, DL, Teepen, JC, Belle, FN, Bárdi, E, Bagnasco, F, Gudmundsdottir, T, Skinner, R, Michel, G, Byrne, J, Øfstaas, H, Jankovic, M, Mazić, MČ, Mader, L, Loonen, J, Garwicz, S, Wiebe, T, Alessi, D, Allodji, RS, Haddy, N, Grabow, D, Kaatsch, P, Kaiser, M, Maule, MM, Jakab, Z, Gunnes, MW, Terenziani, M, Zaletel, LZ, Kuehni, CE, Haupt, R, De vathaire, F, Kremer, LC, Lähteenmäki, PM, Winther, JF, Hjorth, L, Hawkins, MM & Reulen, RC 2023, 'Risk of subsequent primary lymphoma in a cohort of 69,460 five-year survivors of childhood and adolescent cancer in Europe: The PanCareSurFup study', Cancer, vol. 129, no. 3, pp. 426-440. https://doi.org/10.1002/cncr.34561

Sunguc, C, Hawkins, M, Winter, DL, Dudley, IM, Heymer, EJ, Teepen, JC, Allodji, RS, Belle, FN, Bagnasco, F, Byrne, J, Bárdi, E, Ronckers, CM, Haddy, N, Gudmundsdottir, T, Garwicz, S, Jankovic, M, Pal, HJHVD, Mazić, MČ, Schindera, C, Grabow, D, Maule, MM, Kaatsch, P, Fresneau, B, Michel, G, Skinner, R, Wiebe, T, Sacerdote, C, Jakab, Z, Gunnes, MW, Terenziani, M, Winther, JF, Lähteenmäki, PM, Zaletel, LZ, Kuehni, CE, Kremer, LC, Haupt, R, Vathaire, FD, Hjorth, L & Reulen, R 2023, 'Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study', British Journal of Cancer, vol. 128, no. 1, pp. 80-90. https://doi.org/10.1038/s41416-022-02016-w

Byrne, J, Schmidtmann, I, Rashid, H, Hagberg, O, Bagnasco, F, Bardi, E, De Vathaire, F, Essiaf, S, Winther, JF, Frey, E, Gudmundsdottir, T, Haupt, R, Hawkins, MM, Jakab, Z, Jankovic, M, Kaatsch, P, Kremer, LCM, Kuehni, CE, Harila-Saari, A, Levitt, G, Reulen, R, Ronckers, CM, Maule, M, Skinner, R, Steliarova-Foucher, E, Terenziani, M, Zaletel, LZ, Hjorth, L, Garwicz, S & Grabow, D 2022, 'Impact of era of diagnosis on cause-specific late mortality among 77 423 five-year European survivors of childhood and adolescent cancer: the PanCareSurFup consortium', International Journal of Cancer, vol. 150, no. 3, pp. 406-419. https://doi.org/10.1002/ijc.33817

Wang, Y, Reulen, RC, Kremer, LCM, de Vathaire, F, Haupt, R, Zadravec Zaletel, L, Bagnasco, F, Demoor-Goldschmidt, C, van Dorp, WJ, Haddy, N, Hjorth, L, Jakab, Z, Kuehni, CE, Lähteenmäki, PM, van der Pal, HJH, Sacerdote, C, Skinner, R, Terenziani, M, Wesenberg, F, Winther, JF, van Leeuwen, FE, Hawkins, MM, Teepen, JC, van Dalen, EC & Ronckers, CM 2022, 'Male breast cancer after childhood cancer: systematic review and analyses in the PanCareSurFup cohort', European Journal of Cancer, vol. 165, pp. 27-47. https://doi.org/10.1016/j.ejca.2022.01.001

de Baat, EC, Feijen, EAM, Reulen, RC, Allodji, RS, Bagnasco, F, Bardi, E, Belle, FN, Byrne, J, van Dalen, EC, Debiche, G, Diallo, I, Grabow, D, Hjorth, L, Jankovic, M, Kuehni, CE, Levitt, G, Llanas, D, Loonen, J, Zaletel, LZ, Maule, MM, Miligi, L, van der Pal, HJH, Ronckers, CM, Sacerdote, C, Skinner, R, Jakab, Z, Veres, C, Haddy, N, Winter, DL, de Vathaire, F, Hawkins, MM & Kremer, LCM 2022, 'Risk factors for heart failure among pan-European childhood cancer survivors: a PanCareSurFup and ProCardio cohort and nested case-control study', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.21.02944

Abstract

Stephens, C, Winter, D, Reulen, R & Sharif, A 2025, 'Cancer-Related Mortality After Solid Organ Transplantation in England: The EpCOT Study', American Journal of Transplantation, vol. 25, no. 8, Supplement 1, pp. S511-S511. https://doi.org/10.1016/j.ajt.2025.07.1175

Stephens, C, Winter, D, Reulen, R & Sharif, A 2025, 'De Novo Cancer Incidence After Solid Organ Transplantation in England: The EpCOT Study', American Journal of Transplantation, vol. 25, no. 8, Supplement 1, pp. S239-S239. https://doi.org/10.1016/j.ajt.2025.07.526

Stephens, C, Winter, D, Reulen, R & Sharif, A 2025, 'Epidemiology of Cancer After Solid Organ Transplant (EpCOT): Dataset Overview', American Journal of Transplantation, vol. 25, no. 8, Supplement 1, pp. S511-S512. https://doi.org/10.1016/j.ajt.2025.07.1176

Comment/debate

Cesen Mazic, M, Reulen, RC, Jazbec, J & Zadravec Zaletel, L 2022, 'Erratum: Trends in treatment of childhood cancer and subsequent primary neoplasm risk', Radiology and oncology, vol. 56, no. 4, pp. 552-552. https://doi.org/10.2478/raon-2022-0045

View all publications in research portal