Mrs Natalie Rowland (nee Ives) BSc (Hons), MSc

Mrs Natalie Rowland (nee Ives)

Institute of Applied Health Research
Reader in Clinical Trials, Statistics Team Leader

Contact details

Birmingham Clinical Trials Unit (BCTU)
College of Medical and Dental Sciences
Public Health Building
University of Birmingham
B15 2TT

Natalie Rowland (nee Ives) is a Reader in Clinical Trials and the Statistics Team Leader at the Birmingham Clinical Trials Unit (BCTU) in the Institute of Applied Health Research. 

Natalie is interested in the design, conduct and analysis of large scale late phase randomised controlled clinical trials.  She is the Lead Methodologist and Senior Statistician on a substantial and diverse portfolio of high quality clinical trials in the areas of Neuroscience and Parkinson’s Disease, Renal Disease, Coloproctology, Critical Care, Trauma and Primary Care assessing medical, surgical and complex interventions in both adults and children. 

Her research has been published in various high impact scientific journals (NEJM, Lancet, BMJ) and she is a co-applicant on a number of grants funded by the National Institute for Health Research funding streams (HTA, EME and RfPB). 


  • MSc in Statistics, University of Sheffield, 1997
  • BSc (Hons) in Mathematics (1st), University of Leicester, 1995


Teaching Programmes

  • Masters in Public Health (Clinical Trials Module)
  • Masters in Clinical Trials (Further Trial Design Module)
  • Masters in Clinical Oncology
  • Small Group tutor for the Graduate Entry Medical Student course
  • BCTU’s CPD approved Research Methods Course

Other activities

  • Member of the UKCRC Statistics Operational Group committee (2019 - )
  • Member of the Parkinson’s Disease Clinical Studies Group (2013 - )
  • Reviewer for various scientific journals
  • Statistical reviewer for the National Institute for Health Research (HTA, EME, RfPB) and versus Arthritis funding bodies
  • Independent statistician on several Trial Steering and Data Monitoring Committees contributing to the oversight and direction of externally run clinical trials.


Recent publications


Sackley, C, Rick, C, Au, P, Brady , MC, Beaton , G, Burton, C, Caulfield, M, Dickson , S, Dowling, F, Hughes, M, Rowland, N, Jowett, S, Masterson-Algar, P, Nicoll , A, Patel, S, Smith , CH, Woolley, R & Clarke, CE 2020, 'A multi-centre randomised controlled trial to compare the clinical and cost effectiveness of Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson’s disease: a study protocol for a randomised controlled trial', Trials.

PEXIVAS Investigators, Harper, L, Mehta, S & Rowland, N 2020, 'Plasma exchange and glucocorticoids in severe ANCA-associated vasculitis', The New England Journal of Medicine, vol. 382, no. 7, pp. 622-631.

Bhangu, A, Nepogodiev, D, Rowland, N, Magill, L, Glasbey, J, Forde, C, Bisgaard, T, Handley, K, Mehta, S, Morton, D, Pinkney, T & Beggs, A 2020, 'Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial', The Lancet, vol. 395, no. 10222, pp. 417-426.

Markey, K, Mitchell, J, Botfield, H, Ottridge, R, Woolley, R, Westgate, C, Yiangou, A, Alimajstorovic, Z, Ives, N, Taylor, A, Gilligan, L, Jenkinson, C, Arlt, W, Scotton, W, Lavery, G, Mollan, S & Sinclair, A 2020, '11β-hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial', Brain Communications, vol. 2, no. 1, fcz050.

Quraishi, MN, Yalchin, M, Blackwell, C, Segal, JP, Sharma, N, Hawkey, P, McCune, V, Hart, A, Gaya, DR, Ives, N, Magill, L, Loi, S, Hewitt, C, Gerasimidis, K, Loman, N, Hansen, R, McMullan, C, Mathers, J, Quince, C, Crees, N & Iqbal, T 2019, 'STOP-Colitis pilot trial protocol: a prospective, open-label, randomised pilot study to assess two possible routes of faecal microbiota transplant delivery in patients with ulcerative colitis', BMJ open, vol. 9, no. 11, e030659.

Herd, C, Tomlinson, C, Rick, C, Scotton, W, Edwards, J, Ives, N, Clarke, CE & Sinclair, A 2019, 'Cochrane systematic review and meta-analysis of Botulinum toxin for the prevention of migraine', BMJ open, vol. 9, no. 7, e027953.

Green, D, Vassallo, D, Handley, K, Ives, N, Wheatley, K, Chrysochou, C, Hegarty, J, Wright, J, Moss, J, Patel, RK, Deighan, C, Webster, J, Rowe, P, Carr, S, Cross, J, O’Driscoll, J, Sharma, R, Mark, P & Kalra, PA 2019, 'Cardiac structure and function after revascularization versus medical therapy for renal artery stenosis: the ASTRAL Heart echocardiographic sub-study', BMC Nephrology, vol. 20, 220.

Webb, NJ, Woolley, RL, Lambe, T, Frew, E, Brettell, EA, Barsoum, EN, Trompeter, RS, Cummins, C, Wheatley, K & Ives, NJ 2019, 'Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome: the PREDNOS RCT', Health Technology Assessment, vol. 23, no. 26, pp. 1-109.

Webb, NJA, Woolley, R, Lambe, T, Frew, E, Brettell, E, Barsoum, E, Trompeter, RS, Cummins, C, Deeks, J, Wheatley, K & Ives, N 2019, 'Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: Phase III randomised controlled trial and economic evaluation', BMJ, vol. 365, l1800.

Smith, CH, Patel, S, Woolley, RL, Brady, MC, Rick, CE, Halfpenny, R, Rontiris, A, Knox-Smith, L, Dowling, F, Clarke, CE, Au, P, Ives, N, Wheatley, K & Sackley, CM 2019, 'Rating the intelligibility of dysarthic speech amongst people with Parkinson's Disease: a comparison of trained and untrained listeners', Clinical Linguistics & Phonetics, vol. 33, no. 10-11, pp. 1063-1070.

Harper, L, Morgan, M, Chanouzas, D, Caulfield, H, Coughlan, L, Dean, C, Fletcher, K, Cramp, F, Greenfield, S, Hewitt, C, Ives, N, Jowett, S & Daley, A 2018, 'Treatment of fatigue with physical activity and behavioural change support in Vasculitis – study protocol for an open-label randomised controlled feasibility study', BMJ open, vol. 8, no. 10, e023769.

The 2015 European Society of Coloproctology Collaborating Group, Glasbey, JC, Nepogodiev, D, Bhangu, A, Pinkney, T, Chaudhri, S, Morton, D, Mehta, S, Ives, N, Magill, L, Perry, R, Patel, P & Bhangu, A 2018, 'The impact of stapling technique and surgeon specialism on anastomotic failure after right-sided colorectal resection: an international multicentre, prospective audit', Colorectal Disease, vol. 20, no. 11, pp. 1028-1040.

Kyte, D, Bishop, J, Brettell, E, Calvert, M, Cockwell, P, Dutton, M, Eddington, H, Hadley, G, Ives, NJ, Jackson, LJ, Stringer, S & Valente, M 2018, 'Use of an electronic patient-reported outcome measure in the management of patients with advanced chronic kidney disease: the RePROM pilot trial protocol', BMJ open, vol. 8, no. 10, e026080.

Herd, C, Cl, T, Rick, C, Scotton, WJ, Edwards, J, Ives, N, Clarke, CE & Sinclair, A 2018, 'Botulinum toxins for the prevention of migraine in adults', Cochrane Database of Systematic Reviews, no. 6, CD011616.

Review article

Herd, CP, Tomlinson, CL, Rick, C, Scotton, WJ, Edwards, J, Ives, N, Clarke, CE & Sinclair, A 2018, 'Botulinum toxins for the prevention of migraine in adults', Cochrane Database of Systematic Reviews, vol. 6, CD011616.

View all publications in research portal