Mrs Natalie Rowland (née Ives) BSc (Hons), MSc

Mrs Natalie Rowland

Institute of Applied Health Research
Reader in Clinical Trials, Statistics Team Leader

Contact details

Birmingham Clinical Trials Unit (BCTU)
College of Medical and Dental Sciences
Public Health Building
University of Birmingham
B15 2TT

Natalie Rowland (née Ives) is a Reader in Clinical Trials. She is the Statistics Team Leader and member of the Senior Management Team at the Birmingham Clinical Trials Unit (BCTU) in the Institute of Applied Health Research

Natalie is interested in the design, conduct and analysis of large scale late phase randomised controlled clinical trials.  She is the Lead Methodologist and Senior Statistician on a substantial and diverse portfolio of high quality clinical trials in the areas of Neuroscience and Parkinson’s Disease, Renal Disease, Coloproctology, Critical Care, Trauma and Primary Care assessing medical, surgical and complex interventions in both adults and children. 

Her research has been published in various high impact scientific journals (NEJM, Lancet, BMJ) and she is a co-applicant on a number of grants funded by the National Institute for Health Research (NIHR) funding streams (HTA, EME and RfPB). 


  • MSc in Statistics, University of Sheffield, 1997
  • BSc (Hons) in Mathematics (1st), University of Leicester, 1995


Teaching Programmes

Other activities

  • Member of the NIHR Incubator for Methodology (2020-present), and lead for the Incubator Awareness Raising Workstream
  • Member of the UKCRC Statistics Operational Group committee (2019-present)
  • Member of the Parkinson’s Disease Clinical Studies Group (2013-present)
  • Reviewer for various scientific journals
  • Statistical reviewer for the National Institute for Health Research (HTA, EME, RfPB) 
  • Independent statistician on several Trial Steering and Data Monitoring Committees contributing to the oversight and direction of externally run clinical trials


Recent publications


The SUNRRISE Study Group on behalf of the Northwest Research Collaborative and the West Midlands Research Collaborative 2021, 'An international pragmatic randomised controlled trial to compare a single use negative pressure dressing versus a surgeon’s preference of dressing to reduce the incidence of surgical site infection following emergency laparotomy: the SUNRRISE Trial Protocol', Colorectal Disease.

Edwards, N, Price, A, Mehta, S, Hiemstra, TF, Kaur, A, Greasley , PJ, Webb, DJ, Dhaun, N, MacIntyre, IM, Farrah , T, Melville , V, Herrey , A, Slinn, G, Wale, B, Rowland, N, Wheeler, D, Wilkinson, I, Steeds, R, Ferro, C & Townend, J 2021, 'Effects of spironolactone and chlorthalidone on cardiovascular structure and function in chronic kidney disease', Clinical Journal of the American Society of Nephrology, vol. 16, no. 8, CJN.01930221.

Scobie , S, Jowett, S, Lambe, T, Patel, S, Woolley, R, Rowland, N, Rick, C, Smith, C, Brady , M, Clarke, CE & Sackley, C 2021, 'Lee Silverman voice treatment versus standard speech and language therapy versus control in Parkinson’s disease: preliminary cost-consequence analysis of the PD COMM pilot randomised controlled trial', Pilot and Feasibility Studies, vol. 7, no. 1, 154.

Harper, L, Hewitt, C, Litchfield, I, Morgan, M, Chanouzas, D, Caulfield, H, Coughlan, L, Dean, C, Fletcher, K, Cramp, F, Greenfield, S, Rowland, N, Jowett, S, Kodabuckus, S, Tearne, S, Sehmi, S, Edwardson, C, Dawkins, NP & Daley, A 2021, 'Management of fatigue with physical activity and behavioural change support in vasculitis: a feasibility study', Rheumatology.

Markey, K, Mitchell, J, Botfield, H, Ottridge, R, Matthews, T, Krishnan, A, Woolley, R, Westgate, C, Yiangou, A, Alimajstorovic, Z, Shah, P, Rick, C, Ives, N, Taylor, A, Gilligan, L, Jenkinson, C, Arlt, W, Scotton, W, Fairclough, RJ, Singhal, R, Stewart, PM, Tomlinson, JW, Lavery, G, Mollan, S & Sinclair, A 2020, '11β-hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial', Brain Communications, vol. 2, no. 1, fcz050.

Sackley, C, Rick, C, Au, P, Brady , MC, Beaton , G, Burton, C, Caulfield, M, Dickson , S, Dowling, F, Hughes, M, Rowland, N, Jowett, S, Masterson-Algar, P, Nicoll , A, Patel, S, Smith , CH, Woolley, R & Clarke, CE 2020, 'A multi-centre randomised controlled trial to compare the clinical and cost effectiveness of Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson’s disease: a study protocol for a randomised controlled trial', Trials, vol. 21, no. 1, 436.

Kyte, D, Anderson, N, Auti, R, Aiyegbusi, OL, Bishop, J, Bissell, A, Brettell, E, Calvert, M, Chadburn, M, Cockwell, P, Dutton, M, Eddington, H, Forster, E, Hadley, G, Rowland, N, Jackson, L, O’Brien, S, Price, G, Sharpe, K, Stringer, S, Stephenson, G, Verdi, R, Waters, J, Wilcockson, A & Williams, J 2020, 'Development of an electronic patient-reported outcome measure (ePROM) system to aid the management of patients with advanced chronic kidney disease', Journal of Patient-Reported Outcomes, vol. 4, 55.

PEXIVAS Investigators, Harper, L, Mehta, S & Rowland, N 2020, 'Plasma exchange and glucocorticoids in severe ANCA-associated vasculitis', The New England Journal of Medicine, vol. 382, no. 7, pp. 622-631.

Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative 2020, 'Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial', The Lancet, vol. 395, no. 10222, pp. 417-426.

Parretti, H, Rowland, N, Tearne, S, Vince, A, Greenfield, S, Jolly, K, Jebb, SA, Frew, E, Yardley, L, Little, P, Pritchett, R & Daley, A 2020, 'Protocol for the feasibility and acceptability of a brief routine weight management intervention for postnatal women embedded within the national child immunisation programme: randomised controlled cluster feasibility trial with nested qualitative study (PIMMS-WL)', BMJ open, vol. 10, no. 2, e033027.

Green, D, Vassallo, D, Handley, K, Ives, N, Wheatley, K, Chrysochou, C, Hegarty, J, Wright, J, Moss, J, Patel, RK, Deighan, C, Webster, J, Rowe, P, Carr, S, Cross, J, O’Driscoll, J, Sharma, R, Mark, P & Kalra, PA 2019, 'Cardiac structure and function after revascularization versus medical therapy for renal artery stenosis: the ASTRAL Heart echocardiographic sub-study', BMC Nephrology, vol. 20, 220.

Herd, C, Tomlinson, C, Rick, C, Scotton, W, Edwards, J, Ives, N, Clarke, CE & Sinclair, A 2019, 'Cochrane systematic review and meta-analysis of Botulinum toxin for the prevention of migraine', BMJ open, vol. 9, no. 7, e027953.

PREDNOS Collaborative Group 2019, 'Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation', BMJ, vol. 365, l1800.

Smith, CH, Patel, S, Woolley, RL, Brady, MC, Rick, CE, Halfpenny, R, Rontiris, A, Knox-Smith, L, Dowling, F, Clarke, CE, Au, P, Ives, N, Wheatley, K & Sackley, CM 2019, 'Rating the intelligibility of dysarthic speech amongst people with Parkinson's Disease: a comparison of trained and untrained listeners', Clinical Linguistics & Phonetics, vol. 33, no. 10-11, pp. 1063-1070.

Quraishi, MN, Yalchin, M, Blackwell, C, Segal, JP, Sharma, N, Hawkey, P, McCune, V, Hart, A, Gaya, DR, Ives, N, Magill, L, Loi, S, Hewitt, C, Gerasimidis, K, Loman, N, Hansen, R, McMullan, C, Mathers, J, Quince, C, Crees, N & Iqbal, T 2019, 'STOP-Colitis pilot trial protocol: a prospective, open-label, randomised pilot study to assess two possible routes of faecal microbiota transplant delivery in patients with ulcerative colitis', BMJ open, vol. 9, no. 11, e030659.

View all publications in research portal