Recent publications
Article
Ali, S, Zhang, Q, Anwunah, I, Baig, S, Da Silva Xavier, G, Dawson, C, Dassie, F, Tang, Y, Wang, L, Chang, G, Gleeson, P, Warfield, AT, Paisey, RB, Barrett, TG, Maffei, P, Wang, X, Homer, V, Kershaw, M, Geberhiwot, T & Lax, S 2026, 'Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome', Journal of Clinical Endocrinology and Metabolism, vol. 111, no. 1, pp. 33-44. https://doi.org/10.1210/clinem/dgaf356
Brandon, AM, Huisman-Siebinga, H, Barnett, S, Wetherell, P, Kearns, P, Gibson, B, Heaney, N, Smith, O, Baruchel, A, Petit, A, Moore, A, Ogungbenro, K, Huitema, ADR, Veal, GJ & Lax, S 2026, 'Population pharmacokinetics and dose-response relationships of mitoxantrone in children with acute myeloid leukaemia', British Journal of Clinical Pharmacology. https://doi.org/10.1002/bcp.70436
van der Pol, H, Kringelbach, T, Agudo, MM, Stav, GB, Fagereng, GL, Fiocco, M, Falk, RS, Homer, V, Mohammad, SH, Timmer, H, Verlingue, L, Helland, Å, Rohrberg, K, Lassen, U, Halford, S, Jalkanen, K, Juslin, T, Krebs, MG, Oliveira, J, Baltruškevičienė, E, Ojamaa, K, Taskén, K, Gelderblom, H & on behalf of the PRIME-ROSE Consortium 2026, 'Procedures of data merging in precision cancer medicine: the PRIME-ROSE project', Acta Oncologica, vol. 65, pp. 1-8. https://doi.org/10.2340/1651-226X.2026.44889
Keaveney, S, Pratt, G & Lax, S 2025, 'An open-source repository-based tool for quality control of imaging protocol compliance: demonstration in a multicentre MRI study', British Journal of Radiology, vol. 98, no. 1172, pp. 1236–1244. https://doi.org/10.1093/bjr/tqaf089
Moiemen, N, Homer, V, Nice, L, Brock, K, Jenkins, S, Altarrah, K, Imran, R, Tullie, S, Barton, D & Lax, S 2025, 'Efficacy and optimal dose of acetic acid for treating colonised burns wounds (AceticA): a double-blind, single Centre, randomised, controlled phase II trial', Journal of Burn Care and Research. https://doi.org/10.1093/jbcr/iraf228
McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF & Lax, S 2025, 'Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial', BMC Cancer, vol. 25, 56. https://doi.org/10.1186/s12885-024-13383-3
Kirkwood, AA, Goulden, N, Moppett, J, Samarasinghe, S, Hough, R, Rowntree, C, Lawson, S, Kearns, P, Lawson, A, Vora, A & Lax, S 2025, 'High-dose methotrexate in children and young adults with ALL and lymphoblastic lymphoma: Results of the randomized phase III study UKALL 2011', Journal of Clinical Oncology , vol. 43, no. 15, pp. 1810-1823. https://doi.org/10.1200/JCO-24-01851
Steven, NM, Pirrie, S, Jefferson-Hulme, Y, Gaunt, CH, Homer, V & on behalf of the Trial Management Group 2025, 'Rational treatment selection for primary Merkel Cell Carcinoma: a Rational MCC RCT comparing surgery and radiotherapy with parallel observational study', Efficacy and Mechanism Evaluation, vol. 12, no. 12. https://doi.org/10.3310/EEWD6684
Dias, RP, Brock, K, Hu, K, Gupta, R, Martin, U, Peet, A, Wilson, M, Yu-Wai-Man, P, Wright, B, Mollan, S, Kulkarni, A, Meunier, I, Billingham, L, Nagy, Z, Rose, H, Koks, S, Zatyka, M, Astuti, D, Lynch, T, Morrison, KE, Barton, D, Cronier, S, Malpass, R, Evans, R, Malhi, A, Takhar, P, Lamb, A, Esteban-Bueno, G, Młynarski, W, Orssaud, C, Roubertie, A, Homer, V, Barrett, T & Lax, S 2025, 'Sodium valproate, a potential repurposed treatment for the neurodegeneration in Wolfram syndrome (TREATWOLFRAM): trial protocol for a pivotal multicentre, randomised double-blind controlled trial', BMJ open, vol. 15, no. 2, e091495. https://doi.org/10.1136/bmjopen-2024-091495
Bhaskaran, D, Savage, J, Patel, A, Collinson, F, Mant, R, Boele, F, Brazil, L, Meade, S, Buckle, P, Lax, S, Billingham, L & Short, S 2024, 'A randomised phase II trial of temozolomide with or without cannabinoids in patients with recurrent glioblastoma (ARISTOCRAT): Protocol for a multi-centre, double-blind, placebo-controlled trial', BMC Cancer, vol. 24, 83. https://doi.org/10.1186/s12885-023-11792-4
Kong, A, Kirkham, AJ, Savage, JS, Mant, R, Lax, S, Good, J, Forster, MD, Sacco, JJ, Schipani, S, Harrington, KJ, Yap, C & Mehanna, H 2024, 'Results and lessons learnt from the WISTERIA phase I trial combining AZD1775 with cisplatin pre- or post-operatively in head and neck cancer', BJC Reports, vol. 2, no. 1, 6. https://doi.org/10.1038/s44276-023-00026-6
Hirschfield, G, Arndtz, K, Kirkham, A, Chen, Y-Y, Fox, R, Rowe, A, Douglas-Pugh, J, Thorburn, D, Barnes, E, Aithal, GP, Hull, D, Bhandal, K, Olsen, K, Woodward, P, Lax, S, Newsome, P, Smith, D, Kallio, A, Adams, D, Homer, V & Weston, C 2024, 'Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: open-label, multi-centre, single arm, phase II trial', Hepatology Communications, vol. 8, no. 5, e0426. https://doi.org/10.1097/HC9.0000000000000426
Letter
Lawson, A, Kearns, P, Moorman, AV & Lax, S 2025, 'Benchmarking the paediatric T-cell ALL subtype classifier, TALLSorts', British Journal of Haematology. https://doi.org/10.1111/bjh.70263
Lorde, N, Pratt, G, Geberhiwot, T, Ayuk, J, Gittoes, N & Lax, S 2025, 'Paraprotein-Induced spurious hypercalcaemia: Diagnostic pitfalls in two cases', European Journal of Endocrinology, vol. 193, no. 2, pp. K1-K4. https://doi.org/10.1093/ejendo/lvaf151
Review article
Hemming, K, Thompson, J, Kristunas, C, Forbes, A, Watson, S, Bowden, R, McKenzie, JE, Kasza, J & Lax, S 2025, 'The performance of small sample correction methods for controlling type I error when analyzing parallel cluster randomized trials: a systematic review of simulation studies', Journal of Clinical Epidemiology, vol. 185, 111838. https://doi.org/10.1016/j.jclinepi.2025.111838
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