Professor Asif Iqbal PhD

Dr Asif Iqbal

Department of Cardiovascular Sciences
Professor of Inflammation Biology
Birmingham Fellow

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Asif Iqbal is an experimental immunologist with over 15 years of research experience investigating the molecular mechanisms that govern immune cell trafficking, vascular inflammation, and immune mediated inflammatory diseases (IMIDs). His work has defined how immune-stromal interactions, inflammatory mediators, and leukocyte trafficking shape the initiation, persistence, and resolution of inflammation, providing a mechanistic foundation for biomarker discovery and therapeutic development.

He leads a translational research programme spanning discovery science to early phase therapeutic innovation. His group was the first to establish Galectin 9 as a regulator of monocyte, macrophage, and platelet function in cardiovascular disease and IMIDs, positioning it as both a biomarker and therapeutic target. He also leads the development of next generation IL 17 therapeutics, including a patented IL 17 neutralising antibody and novel small molecule inhibitors, a first in class approach for IMIDs.

His research integrates patient cohorts, experimental medicine platforms, and advanced multi omics to accelerate translation for patient benefit.

Qualifications

  • PhD in Immunopharmacology (2011)
  • MSc in Immunology of Infectious Diseases (2007)
  • BSc (Hons) in Biomedical Sciences (2006)

Biography

Professor Asif Iqbal qualified with a BSc (Hons) in Biomedical Sciences from the University of Surrey in 2006.

He went on to study for an MSc in Immunology of infectious diseases from the London School of Hygiene and Tropical Medicine, University of London, completing in 2007.

He then secured a joint industrial case award with the BBSRC and UCB Celltech to pursue a PhD at the William Harvey Research Institute, QMUL, in the laboratory of Professor Mauro Perretti.

He graduated in 2011 and joined the laboratory of Professor David Greaves at the Sir William Dunn School of Pathology, University of Oxford as a post-doctoral research fellow.

In 2017 Asif was awarded a Birmingham Fellowship to establish his own research group at the University of Birmingham.

Professor Asif Iqbal along with Professor Ed Rainger and Dr Myriam Chimen talk about their work to understand how inflammation affects the Cardiovascular System with the goal to transfer their findings to benefit patients.

Postgraduate supervision

For any doctoral research enquiries, please email: A.J.Iqbal@bham.ac.uk 

Research

Asif has been studying the role of inflammation in cardiovascular disease and other chronic inflammatory pathologies and how we can harness endogenous mediators to regulate this process. Inflammation has been the central theme throughout his research, with particular emphasis on the anti-inflammatory mechanisms at play in both acute and chronic immune models of inflammation. His doctoral training focused on the Galectins and their role in regulating leukocyte trafficking and activation of immune cells. His post-doctoral research was centred on the role chemokines play monocyte/macrophage recruitment and retention in the context of atherosclerosis, a disease process that occurs in major arteries causing angina, heart attack, stroke and peripheral arterial disease. Following his award of a Birmingham fellowship Asif now aims to bring these themes together; to investigate the actions of the Galectins in pre-clinical models of vascular inflammation and atherosclerosis, and the mechanisms by which they regulate monocyte recruitment.

Department of Cardiovascular Sciences website

Leukocyte Trafficking

Publications

For a list of Asif's publications please click here.

View all publications in research portal