Dr Jamie Lewis BSc(Hons), PhD

Dr Jamie Lewis

School of Chemistry
Royal Society University Research Fellow
Assistant Professor in Supramolecular Chemistry

Contact details

School of Chemistry
University of Birmingham
B15 2TT

Jamie Lewis is an Assistant Professor in Supramolecular Chemistry and Royal Society University Research Fellow within the School of Chemistry.

Jamie’s research interests are in various areas of synthetic supramolecular chemistry, including metal-organic self-assembly, host-guest chemistry, and mechanically interlocked molecules.

He undertook research training at the University of Otago, New Zealand, with Professor James Crowley, and the University of Southampton, UK, with Professor Steve Goldup. Jamie established his independent research programme as an Imperial College Research Fellow, before joining the University of Birmingham in October 2022.

Further details of Jamie’s research can be found on his personal webpage.


  • Member of the Royal Society of Chemistry, 2016
  • PhD, 2014
  • BSc(Hons) in Chemistry, 1st Class, 2011


Jamie graduated in 2010 from the University of Otago, New Zealand, with a first class BSc (Hons) in Chemistry. He then completed a PhD (2011-2014) at the same institute under the supervision of Professor James Crowley, investigating metallo-supramolecular host architectures as drug delivery vectors.

Following this, he took up a postdoctoral research assistant position working in the group of Professor Steve Goldup, initially at Queen Mary, University of London and then at the University of Southampton. During this time his main research focus was the development of synthetic methodologies to access structurally sophisticated mechanically interlocked molecules.

The subsequent award of a Marie Sklodowska-Curie Individual Fellowship in 2015 allowed him to continue his research in the Goldup Group on mechanically interlocked molecules, and expand his work to include investigations on their coordination chemistry.

In October 2017 Jamie secured an Imperial College Research Fellowship through which he began his own independent programme of research. He led a small group of young researchers, publishing articles on low-symmetry metal-organic cages, and functional interlocked molecules. During his time at Imperial College London, Jamie was engaged in a variety of undergraduate and postgraduate teaching activities. Most notably he was the course coordinator for the year-4 topic Supramolecular Chemistry.

In October 2022 Jamie moved to the University of Birmingham as an Assistant Professor and Royal Society University Research Fellow.


  • Y1 Organic Chemistry small group tutor
  • Y2 Organic Chemistry small group tutor


  • Metal-organic host systems
  • Self-assembled architectures
  • Mechanically interlocked molecules

Other activities

Member of the RSC Macrocyclic and Supramolecular Chemistry interest group committee


Recent publications


Molinska, P, Tarzia, A, Male, L, Jelfs, KE & Lewis, JEM 2023, 'Diastereoselective Self‐Assembly of Low‐Symmetry PdnL2n Nanocages through Coordination‐Sphere Engineering', Angewandte Chemie (International Edition) . https://doi.org/10.1002/anie.202315451

Molinska, P, Tarzia, A, Male, L, Jelfs, KE & Lewis, J 2023, 'Diastereoselective Self‐Assembly of Low‐Symmetry PdnL2n Nanocages through Coordination‐Sphere Engineering', Angewandte Chemie. https://doi.org/10.1002/ange.202315451

Hoyas pérez, N, Sherin, PS, Posligua, V, Greenfield, JL, Fuchter, MJ, Jelfs, KE, Kuimova, MK & Lewis, JEM 2022, 'Emerging properties from mechanical tethering within a post-synthetically functionalised catenane scaffold', Chemical Science, vol. 13, no. 38, pp. 11368-11375. https://doi.org/10.1039/D2SC04101D

Lewis, J 2022, 'Pseudo-heterolepticity in low-symmetry metal-organic cages', Angewandte Chemie International Edition, vol. 61, no. 44, e202212392. https://doi.org/10.1002/anie.202212392

Yu, S, Kupryakov, A, Lewis, JEM, Martí-Centelles, V, Goldup, SM, Pozzo, JL, Jonusauskas, G & McClenaghan, ND 2021, 'Damming an electronic energy reservoir: ion-regulated electronic energy shuttling in a [2]rotaxane', Chemical Science, vol. 12, no. 26, pp. 9196-9200. https://doi.org/10.1039/d1sc02225c

Tarzia, A, Lewis, J & Jelfs, KE 2021, 'High-throughput computational evaluation of low symmetry Pd2L4 cages to aid in system design', Angewandte Chemie (International Edition) , vol. 60, no. 38, pp. 20879-20887. https://doi.org/10.1002/anie.202106721

Lewis, JEM 2021, 'Multi-functional, low symmetry Pd2L4 nanocage libraries', Chemistry - A European Journal, vol. 27, no. 13, pp. 4454-4460. https://doi.org/10.1002/chem.202005363

Cirulli, M, Salvadori, E, Zhang, Z, Dommett, M, Tuna, F, Bamberger, H, Lewis, JEM, Kaur, A, Tizzard, GJ, Slageren, J, Crespo‐otero, R, Goldup, SM & Roessler, MM 2021, 'Rotaxane CoII complexes as field-induced single-ion magnets', Angewandte Chemie (International Edition) , vol. 60, no. 29, pp. 16051-16058. https://doi.org/10.1002/anie.202103596

Kench, T, Summers, PA, Kuimova, MK, Lewis, JEM & Vilar, R 2021, 'Rotaxanes as cages to control DNA binding, cytotoxicity, and cellular uptake of a small molecule', Angewandte Chemie - International Edition, vol. 60, no. 19, pp. 10928-10934. https://doi.org/10.1002/anie.202100151

Lewis, JEM, Tarzia, A, White, AJP & Jelfs, KE 2020, 'Conformational control of Pd2L4 assemblies with unsymmetrical ligands', Chemical Science, vol. 11, no. 3, pp. 677-683. https://doi.org/10.1039/c9sc05534g

Review article

Lewis, J 2023, 'Developing sophisticated microenvironments in metal-organic cages', Trends in Chemistry, vol. 5, no. 10, pp. 717-719. https://doi.org/10.1016/j.trechem.2023.06.003

Lewis, J 2023, 'Stereoselective synthesis of topologically chiral molecular entanglements', Chem. https://doi.org/10.1016/j.chempr.2023.03.008

Lewis, J 2022, 'Molecular engineering of confined space in metal-organic cages', Chemical Communications , vol. 58, pp. 13873-13886. https://doi.org/10.1039/D2CC05560K

Martín Díaz, AE & Lewis, JEM 2021, 'Structural flexibility in metal-organic cages', Frontiers in Chemistry, vol. 9, 706462. https://doi.org/10.3389/fchem.2021.706462

Lewis, JEM 2020, 'Knotting to See Here', Chem, vol. 6, no. 1, pp. 14-15. https://doi.org/10.1016/j.chempr.2019.12.017

View all publications in research portal