Dr Lisa J Hill PhD

Image of Lisa Hill

Institute of Clinical Sciences
Lecturer - Teaching & Research
Discovery and Translational Science Theme Lead

Contact details

Telephone
+44 (0)121 414 6620
Email
l.j.hill@bham.ac.uk
Twitter
@Neuroscience_Dr
View my research portal
Address
Institute of Clinical Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Lisa Hill is a Lecturer based within the Neuroscience & Ophthalmology group and specialises in developing and translating new treatments for degenerative ocular diseases, including Age-related Macular Degeneration and Glaucoma. Lisa has a keen interest in developing novel methods for drug delivery into the eye. 

Qualifications

  • PhD in Medicine, 2015
  • BMedSc Neuroscience, 2010

Biography

Lisa has a background in Neuroscience and obtained her PhD at the University of Birmingham in 2015. Lisa’s PhD research investigated the role of cytokines and growth factors associated with ocular scarring diseases. After graduating she had a post-doctoral position with Professors Antonio Belli, Ann Logan and Liam Grover working in the fields of Neurotrauma, Ophthalmology and biomaterials science. As a lecturer (appointed February 2018) she now leads research in the fields of translational ophthalmology and ocular drug delivery and has a particular interest in developing new treatments for ocular scarring and degenerative diseases including, Glaucoma and Age-related Macular Degeneration.  Lisa has current collaborative projects with the University of Melbourne, the University of California Irvine, Queen’s University Belfast, Aston University and Moorfields Eye Hospital as well as international industrial partners.   

Teaching

Postgraduate supervision

  • Post-graduate supervisor
  • Clinical BSc supervisor

Research

Lisa has current funded projects related to the following projects:

  • Developing topical therapies for early interventions for AMD
  • Proteomic profiling of ocular inflammatory diseases
  • Investigating anti-scarring compounds to treat anterior segment fibrosis in Glaucoma
  • Tissue engineering/3D modelling of ocular microenvironments for evaluating novel therapies
  • Developing anti-scarring eye drops and slow release for anterior segment and retinal fibrosis
  • Understanding the role of autophagy in corneal scarring
  • Research affiliated with the National Institute for Health Research (NIHR) Surgical Reconstruction and Microbiology Research Centre (SRMRC) 

Read more about Lisa's research on her ResearchGate profile.

Other activities

Lisa is actively involved in organising and participating in public/patient events (e.g. Brain Awareness Week; Macular Society patient groups) and actively promote science via social media. Lisa is also organising and hosting the 4th Annual “Women in Vision UK” event in December 2020 at the University of Birmingham.

Memberships/Committee roles

  • Current member of
    • The Association for Research in Vision and Ophthalmology
    • The British Inflammation Research Association
    • Women In Vision UK.
  • Current academic lead for Postdoctoral/Early Researcher Career Development and Training at the University of Birmingham

Publications

Recent publications

Article

Nirbhavane, P, Sharma, G, Singh, B, Begum, G, Jones, M-C, Rauz, S, Vincent, R, Denniston, A, Hill, LJ & Katare, OP 2020, 'Triamcinolone acetonide loaded-cationic nano-lipoidal formulation for uveitis: evidences of improved biopharmaceutical performance and anti-inflammatory activity', Colloids and Surfaces B: Biointerfaces, vol. 190, 110902. https://doi.org/10.1016/j.colsurfb.2020.110902

Chouhan, G, Moakes, RJA, Esmaeili, M, Hill, LJ, deCogan, F, Hardwicke, J, Rauz, S, Logan, A & Grover, LM 2019, 'A self-healing hydrogel eye drop for the sustained delivery of decorin to prevent corneal scarring', Biomaterials, vol. 210, pp. 41-50. https://doi.org/10.1016/j.biomaterials.2019.04.013

De Silva, E, Hill, LJ, Downie, L & Chinnery, HR 2019, 'The effects of aging on corneal and ocular surface homeostasis in mice', Investigative Ophthalmology & Visual Science (IOVS), vol. 60, no. 7, pp. 2705-2715. https://doi.org/10.1167/iovs.19-26631

Hill, LJ, Moakes, R, Butt, G, Brock, K, Vincent, R, Williams, R, Barnes, N, Wallace, G, Rauz, S, Logan, A & Grover, L 2018, 'Sustained release of decorin to the surface of the eye enables scarless corneal regeneration', npj Regenerative Medicine, vol. 3, 23. https://doi.org/10.1038/s41536-018-0061-4

Hill, LJ, Mead, B, Thomas, CN, Foale, S, Feinstein, E, Berry, M, Blanch, RJ, Ahmed, Z & Logan, A 2018, 'TGF-β-induced IOP elevations are mediated by RhoA in the early but not the late fibrotic phase of open angle glaucoma', Molecular Vision, vol. 24, pp. 712-726.

Williams, AC & Hill, LJ 2018, 'Nicotinamide's Ups and Downs: Consequences for Fertility, Development, Longevity and Diseases of Poverty and Affluence', International Journal of Tryptophan Research, vol. 11, pp. 1-8. https://doi.org/10.1177/1178646918802289

Hill, LJ, Di Pietro, V, Hazeldine, J, Davies, D, Toman, E, Logan, A & Belli, A 2018, 'Author Correction: Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury', Scientific Reports, vol. 8, 4572. https://doi.org/10.1038/s41598-018-22951-0

Hill, L, Di Pietro, V, Hazeldine, J, Davies, D, Logan, A, Belli, A & Toman, E 2017, 'Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury', Scientific Reports, vol. 7, 5002. https://doi.org/10.1038/s41598-017-04722-5

Di Pietro, V, Ragusa, M, Davies, D, Su, Z, Hazeldine, J, Lazzarino, G, Hill, LJ, Crombie, N, Foster, M, Purrello, M, Logan, A & Belli, A 2017, 'MicroRNAs as novel biomarkers for the diagnosis and prognosis of mild and severe traumatic brain injury', Journal of Neurotrauma, vol. 34, no. 11, pp. 1948-1956. https://doi.org/10.1089/neu.2016.4857

Review article

Bennett, N, Chinnery, HR, Downie, L, Hill, LJ & Grover, L 2020, 'Material, immunological, and practical perspectives on eye drop formulation', Advanced Functional Materials, vol. 30, no. 14, 1908476. https://doi.org/10.1002/adfm.201908476

Scotton, WJ, Hill, LJ, Williams, AC & Barnes, NM 2019, 'Serotonin syndrome: pathophysiology, clinical features, management, and potential future directions', International Journal of Tryptophan Research, vol. 12, pp. 1-14. https://doi.org/10.1177/1178646919873925

Williams, AC & Hill, LJ 2019, 'Nicotinamide and demographic and disease transitions: moderation is best', International Journal of Tryptophan Research, vol. 12, pp. 1-18. https://doi.org/10.1177/1178646919855940

Williams, AC & Hill, LJ 2019, 'Nicotinamide as independent variable for intelligence, fertility, and health: origin of human creative explosions?', International Journal of Tryptophan Research, vol. 12, pp. 1-15. https://doi.org/10.1177/1178646919855944

Jiao, H, Hill, LJ, Downie, LE & Chinnery, HR 2019, 'Anterior segment optical coherence tomography: its application in clinical practice and experimental models of disease', Clinical and Experimental Optometry, vol. 102, no. 3, pp. 208-217. https://doi.org/10.1111/cxo.12835

Cooke, M, Jones, S, Ter Horst, B, Moiemen, N, Snow, M, Chouhan, G, Hill, LJ, Esmaeli, M, Moakes, R, Holton, J, Nandra, R, Williams, R, Smith, AM & Grover, L 2018, 'Structuring of hydrogels across multiple length scales for biomedical applications', Advanced Materials, vol. 30, no. 14, 1705013. https://doi.org/10.1002/adma.201705013

View all publications in research portal