Recent publications
Article
Klein, F, Veiga-Villauriz, C, Börsch, A, Maio, S, Palmer, S, Dhalla, F, Handel, AE, Zuklys, S, Calvo-Asensio, I, Musette, L, Deadman, ME, White, AJ, Lucas, B, Anderson, G & Holländer, GA 2023, 'Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells', Nature Communications, vol. 14, no. 1, 4071. https://doi.org/10.1038/s41467-023-39722-9
White, AJ, Parnell, SM, Handel, A, Maio, S, Bacon, A, Cosway, EJ, Lucas, B, James, KD, Cowan, JE, Jenkinson, WE, Hollander, GA & Anderson, G 2023, 'Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk', Journal of Immunology, vol. 210, no. 1, pp. 40-49. https://doi.org/10.4049/jimmunol.2200609
Lucas, B, White, AJ, Klein, F, Veiga-Villauriz, C, Handel, A, Bacon, A, Cosway, EJ, James, KD, Parnell, SM, Ohigashi, I, Takahama, Y, Jenkinson, WE, Hollander, GA, Lu, W-Y & Anderson, G 2023, 'Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla', Nature Communications, vol. 14, no. 1, 2066. https://doi.org/10.1038/s41467-023-37589-4
Cosway, EJ, James, KD, White, AJ, Parnell, SM, Bacon, A, McKenzie, ANJ, Jenkinson, WE & Anderson, G 2023, 'The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration', Nature Communications, vol. 14, no. 1, 7201. https://doi.org/10.1038/s41467-023-43072-x
James, KD, White, AJ, Jenkinson, WE & Anderson, G 2023, 'The medulla controls effector primed γδT-cell development in the adult mouse thymus', European Journal of Immunology, vol. 53, no. 6, e2350388. https://doi.org/10.1002/eji.202350388
Cosway, EJ, White, AJ, Parnell, SM, Schweighoffer, E, Jolin, HE, Bacon, A, Rodewald, HR, Tybulewicz, V, McKenzie, ANJ, Jenkinson, WE & Anderson, G 2022, 'Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration', Science Immunology, vol. 7, no. 69, eabn3286. https://doi.org/10.1126/sciimmunol.abn3286
Maneta, E, Fultang, L, Taylor, J, Pugh, M, Jenkinson, W, Anderson, G, Coomarasamy, A, Kilby, MD, Lissauer, DM, Mussai, F & De Santo, C 2022, 'G-CSF induces CD15+ CD14+ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment', Clinical and Translational Immunology, vol. 11, no. 5, e1395. https://doi.org/10.1002/cti2.1395
Ferreirinha, P, Ribeiro, C, Morimoto, J, Landry, JJM, Matsumoto, M, Meireles, C, White, AJ, Ohigashi, I, Araújo, L, Benes, V, Takahama, Y, Anderson, G, Matsumoto, M & Alves, NL 2021, 'A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation', European Journal of Immunology, vol. 51, no. 2, pp. 311-318. https://doi.org/10.1002/eji.202048764
Rota, IA, Handel, AE, Maio, S, Klein, F, Dhalla, F, Deadman, ME, Cheuk, S, Newman, JA, Michaels, YS, Zuklys, S, Prevot, N, Hublitz, P, Charles, PD, Gkazi, AS, Adamopoulou, E, Qasim, W, Davies, EG, Hanson, I, Pagnamenta, AT, Camps, C, Dreau, HM, White, A, James, K, Fischer, R, Gileadi, O, Taylor, JC, Fulga, T, Christoffer Lagerholm, B, Anderson, G, Sezgin, E & Holländer, GA 2021, 'FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency', Science Advances, vol. 7, no. 49, eabj9247. https://doi.org/10.1126/sciadv.abj9247
Alawam, AS, Cosway, EJ, James, KD, Lucas, B, Bacon, A, Parnell, SM, White, AJ, Jenkinson, WE & Anderson, G 2021, 'Failures in thymus medulla regeneration during immune recovery cause tolerance loss and prime recipients for auto-GVHD', The Journal of Experimental Medicine, vol. 219, no. 2, e20211239. https://doi.org/10.1084/jem.20211239
James, KD, Legler, DF, Purvanov, V, Ohigashi, I, Takahama, Y, Parnell, SM, White, AJ, Jenkinson, WE & Anderson, G 2021, 'Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus', Blood Advances, vol. 5, no. 1, pp. 99-112. https://doi.org/10.1182/bloodadvances.2020003192
Paolino, M, Koglgruber, R, Cronin, SJF, Uribesalgo, I, Rauscher, E, Harreiter, J, Schuster, M, Bancher-Todesca, D, Pranjic, B, Novatchkova, M, Fededa, JP, White, AJ, Sigl, V, Dekan, S, Penz, T, Bock, C, Kenner, L, Holländer, GA, Anderson, G, Kautzky-Willer, A & Penninger, JM 2021, 'RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy', Nature, vol. 589, no. 7842, pp. 442-447. https://doi.org/10.1038/s41586-020-03071-0
Preprint
Ohigashi, I, White, AJ, Yang, M-T, Fujimori, S, Tanaka, Y, Jacques, A, Kiyonari, H, Matsushita, Y, Turan, S, Kelly, MC, Anderson, G & Takahama, Y 2023 'Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium' bioRxiv. https://doi.org/10.1101/2023.10.03.560657
Review article
James, KD, Jenkinson, WE & Anderson, G 2021, 'Non-Epithelial Stromal Cells in Thymus Development and Function', Frontiers in immunology, vol. 12, 634367. https://doi.org/10.3389/fimmu.2021.634367
Cosway, EJ, James, KD, Lucas, B, Anderson, G & White, AJ 2021, 'The thymus medulla and its control of αβT cell development', Seminars in immunopathology, vol. 43, no. 1, pp. 15-27. https://doi.org/10.1007/s00281-020-00830-z
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