Dr Marietta Iacucci MD, PhD

Marietta Iacucci

Institute of Immunology and Immunotherapy
Honorary Associate Professor in Gastroenterology

Contact details

Institute of Translational of Medicine
Immunology & Immunotherapy
Heritage Building Research & Development
University Hospital Birmingham UK
Birmingham B15 2TT


  • MD
  • PhD


Marietta Iacucci received her Medical Degree and Gastroenterology trainingfrom the University of Rome “La Sapienza” School of Medicine. She did her PhD at theUniversity of Tor Vergata of Rome, Italy & Imperial College London, UK. She worked as gastroenterology consultant in Italy at S. Camillo Hospital, Rome. She spent two years in London and Cambridge, UK and in Mainz, Germany, Milan, Italy and Tokyo, Japan.

She moved from Italy to the Division of Gastroenterology, University of Calgary, Canadaas Clinical Associate Professor of Gastroenterology in 2011. In Canada, she established anadvanced endoscopic platform for IBD and cancer by introducing novel imaging andconfocal endomicroscopy. In August 2016, she joined University of Birmingham as thereader in gastroenterology and honorary consultant.

Her research is focused on advanced endoscopic imaging such as dye, virtual electronic chromoendoscopy and confocal laser endomicroscopy in the diagnosis of gastrointestinal disease, advanced polypectomy (EMR, ESD) and management of inflammatory bowel disease. She has published many manuscripts and she has been invited to deliver lectures at many international and national conferences endoscopy in IBD and Gastrointestinal cancer. Marietta is theme lead for the NIHR Birmingham Biomedical Research Centre's inflammatory gastroenterology theme.


  • Developed teaching programs for Canadian Association of Gastroenterology
  • Delivered advanced endoscopic imaging teaching at the American Society of Gastrointestinal Endoscopy at Chicago
  • Lectured at Mentoring in Inflammatory Bowel Disease at Toronto
  • Developed several education and training modules at international level
  • Teaching and training of endoscopy nurses at a national level

Postgraduate supervision

Dr Iacucci supervised several postgraduate trainees at the University of Calgary, Canada.

If you are interesting in studying any of these subject areas please contact Dr Marietta Iacucci directly, or for any general doctoral research enquiries, please email mds-gradschool@contacts.bham.ac.uk.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.


Advanced endoscopic technologies such as dye, virtual chromoendoscopy with optical magnification, probe confocal laser endomicroscopy to assess inflammation in IBD and early detection of GI cancer. Novel endoscopic imaging and endoscopic molecular labelling to stratify therapy in gastrointestinal disease.

Developing education training modules using advanced technologies.

Other activities

  • Chair of the Canadian Association of Gastroenterology training program accredited "Endoscopy scoring in IBD”
  • American Society of Gastrointestinal Endoscopy Training course of Novel endoscopic techniques in IBD Chicago 2014
  • Crohns & Colitis Canada IBD mentoring course "novel endoscopic techniques in IBD", Toronto 2012
  • Crohns & Colitis Canada IBD mentoring course "Cancer surveillance in IBD with novel endoscopic techniques", Toronto 2013
  • Crohns & Colitis Canada IBD mentoring course "Cancer surveillance in IBD with novel endoscopic techniques", Vancouver 2014
  • Canadian Society of Gastroenterology Nurses & Associates endoscopy (CSGNA) course "Novel endoscopic techniques: new toys or tools", CSGNA 2013, Banff Canada


Recent publications


Iacucci, M, Bonovas, S, Bazarova, A, Cannatelli, R, Ingram, RJM, Labarile, N, Nardone, OM, Parigi, TL, Piovani, D, Siau, K, Smith, SCL, Zammarchi, I, Ferraz, JGP, Fiorino, G, Kiesslich, R, Panaccione, R, Parra-Blanco, A, Principi, M, Tontini, GE, Uraoka, T & Ghosh, S 2024, 'Validation of a new optical diagnosis training module to improve dysplasia characterization in inflammatory bowel disease: a multicenter international study', Gastrointestinal Endoscopy, vol. 99, no. 5, pp. 756-766.e4. https://doi.org/10.1016/j.gie.2023.11.018

Iacucci, M, Parigi, TL, Del Amor, R, Meseguer, P, Mandelli, G, Bozzola, A, Bazarova, A, Bhandari, P, Bisschops, R, Danese, S, De Hertogh, G, Ferraz, JG, Goetz, M, Grisan, E, Gui, X, Hayee, B, Kiesslich, R, Lazarev, M, Panaccione, R, Parra-Blanco, A, Pastorelli, L, Rath, T, Røyset, ES, Tontini, GE, Vieth, M, Zardo, D, Ghosh, S, Naranjo, V & Villanacci, V 2023, 'Artificial Intelligence Enabled Histological Prediction of Remission or Activity and Clinical Outcomes in Ulcerative Colitis', Gastroenterology, vol. 164, no. 7, pp. 1180-1188.e2. https://doi.org/10.1053/j.gastro.2023.02.031

Iacucci, M, Jeffery, L, Acharjee, A, Grisan, E, Buda, A, Nardone, O, Smith, S, Labarile, N, Zardo , D, Ungar, B, Hunter, S, Mao, R, Cannatelli, R, Shivaji, U, Parigi, TL, Reynolds, G, Gkoutos, G & Ghosh, S 2023, 'Computer-Aided Imaging Analysis of Probe-Based Confocal Laser Endomicroscopy With Molecular Labeling and Gene Expression Identifies Markers of Response to Biological Therapy in IBD Patients: The Endo-Omics Study', Inflammatory Bowel Diseases, vol. 29, no. 9, izac233, pp. 1409–1420. https://doi.org/10.1093/ibd/izac233

Nardone, OM, Iacucci, M, Villanacci, V, Peyrin‐Biroulet, L, Ghosh, S, Danese, S & Parigi, TL 2023, 'Real‐world use of endoscopic and histological indices in ulcerative colitis: Results of a global survey', United European Gastroenterology Journal. https://doi.org/10.1002/ueg2.12423

Nardone, OM, Snir, Y, Hodson, J, Cannatelli, R, Labarile, N, Siau, K, Hassan, C, Yanai, H, Dotan, I, Ghosh, S & Iacucci, M 2022, 'Advanced technology for assessment of endoscopic and histological activity in ulcerative colitis: a systematic review and meta-analysis', Therapeutic Advances in Gastroenterology, vol. 15, pp. 1-14. https://doi.org/10.1177/17562848221092594

Awasthi, A, Barbour, J, Beggs, A, Bhandari, P, Blakeway, D, Brookes, M, Brown, J, Brown, M, Caldwell, G, Clokie, S, Colleypriest, B, Conlin, A, Silva, SD, Caestecker, JD, Deeks, J, Dhar, A, Dilworth, M, Fogden, E, Foley, S, Ghosh, D, Grellier, L, Hart, A, Hoque, SS, Iacucci, M, Iqbal, T, James, J, Jarvis, M, Jayaprakash, A, Keshav, S, Magill, L, Matthews, G, Mawdsley, J, McLaughlin, S, Mehta, S, Monahan, K, Morton, D, Murugesan, S, Parkes, M, Pestinger, V, Probert, C, Ramadas, A, Rettino, A, Sebastian, S, Sharma, N, Griffiths, M, Stockton, J, Subramanian, V, Suggett, N, Taniere, P, Teare, J, Verma, AM & Wallis, Y 2021, 'Enhanced neoplasia detection in chronic ulcerative colitis: the ENDCaP-C diagnostic accuracy study', Efficacy and Mechanism Evaluation, vol. 8, no. 1, pp. 1-87. https://doi.org/10.3310/eme08010

Smith, SCL, Banbury, C, Zardo, D, Cannatelli, R, Nardone, OM, Shivaji, UN, Ghosh, S, Oppenheimer, PG & Iacucci, M 2021, 'Raman spectroscopy accurately differentiates mucosal healing from non-healing and biochemical changes following biological therapy in inflammatory bowel disease', PLoS ONE, vol. 16, no. 6, e0252210. https://doi.org/10.1371/journal.pone.0252210

Smith, SCL, Siau, K, Cannatelli, R, Antonelli, G, Shivaji, UN, Ghosh, S, Saltzman, JR, Hassan, C & Iacucci, M 2021, 'Training methods in optical diagnosis and characterization of colorectal polyps: a systematic review and meta-analysis', Endoscopy International Open, vol. 9, no. 5, pp. E716-E726. https://doi.org/10.1055/a-1381-7181

Iacucci, M, Jeffery, L, Acharjee, A, Nardone, OM, Zardo, D, Smith, SCL, Bazarova, A, Cannatelli, R, Shivaji, UN, Williams, J, Gkoutos, G & Ghosh, S 2021, 'Ultra-high magnification endocytoscopy and molecular markers for defining endoscopic and histologic remission in ulcerative colitis—an exploratory study to define deep remission', Inflammatory Bowel Diseases, vol. 27, no. 11, izab059, pp. 1719-1730. https://doi.org/10.1093/ibd/izab059

Smith, S, Bazarova, A, Ejenavi , E, Qurashi, M, Shivaji, U, Harvey , PR, Slaney, E, McFarlane, M, Baker, G, Elnagar, M, Yuzari , S, Gkoutos, GV, Ghosh, S & Iacucci, M 2020, 'A multicentre development and validation study of a novel Lower Gastrointestinal Bleeding score-The Birmingham Score', International journal of colorectal disease, vol. 35, no. 2, pp. 285–293. https://doi.org/10.1007/s00384-019-03459-z

Iacucci, M, Smith, SCL, Bazarova, A, Shivaji, U, Bhandari, P, Cannatelli, R, Daperno, M, Ferraz, J, Goetz, M, Gui, X, Hayee, B, De Hertogh, G, Lazarev, M, Li, J, Nardone, O, Parra-Blanco, A, Pastorelli, L, Panaccione, R, Occhipinti, V, Rath, T, Tontini, GE, Vieth, M, Villanacci, V, Zardo , D, Bisschops, R, Kiesslich, R & Ghosh, S 2020, 'An international multicenter real-life prospective study of electronic chromoendoscopy score PICaSSO in ulcerative colitis', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.12.024

Iacucci, M, Ghosh, S, Cannatelli, R, Gui, XS, Bazarova, A, Zardo , D, Gkoutos, G, Lethebe, BC, Kaplan, GG, Panaccione, R, Kiesslich, R & Ghosh, S 2020, 'Assessment of endoscopic healing by using advanced technologies reflects histologic healing in ulcerative colitis', Journal of Crohn's & Colitis, vol. 14, no. 9, pp. 1282-1289. https://doi.org/10.1093/ecco-jcc/jjaa056


Nardone, OM, Ghosh, S & Iacucci, M 2022, 'Endoscopy and histology in inflammatory bowel diseases patients: complementary or alternatives?—author’s reply', United European Gastroenterology Journal, vol. 10, no. 3, pp. 344-345. https://doi.org/10.1002/ueg2.12214

Review article

Nardone, OM, Cannatelli, R, Ghosh, S & Iacucci, M 2022, 'New endoscopic tools in inflammatory bowel disease', United European Gastroenterology Journal, vol. 10, no. 10, pp. 1103-1112. https://doi.org/10.1002/ueg2.12316

Iacucci, M, Cannatelli, R, Labarile, N, Mao, R, Panaccione, R, Danese, S, Kochhar, GS, Ghosh, S & Shen, B 2020, 'Endoscopy in inflammatory bowel diseases during the COVID-19 pandemic and post-pandemic period', The Lancet Gastroenterology & Hepatology, vol. 5, no. 6, pp. 598-606. https://doi.org/10.1016/S2468-1253(20)30119-9

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