Dr Helen Parry MBChB, MSc, PhD, MRCP, FRCPath

Dr Helen Parry

Institute of Immunology and Immunotherapy
Associate Professor

Contact details

Institute of Immunology and Immunotherapy
Cancer Sciences Building
Mindelsohn Way
University of Birmingham
B15 2TT

Dr Helen Parry is an Associate Professor at The University of Birmingham and honorary consultant at the Queen Elizabeth Hospital, Birmingham. She has received funding from The Wellcome Trust (PhD fellowship), Academy of medical sciences (current), British Society of Haematology (current) and Queen Elizabeth Hospital charity (current education grant) funding and completed her NIHR academic clinical lecturership in 2021.

Her current research areas include secondary immunodeficiency in haematological malignancies, and in particular Chronic Lymphocytic Leukaemia (CLL), for which she co-authored the British clinical guidelines. Her work involves studying patient immunity and the impact of novel therapies used to treat CLL and how we can improve current vaccination strategies to minimise infection risk. She is also interested in optimising the delivery of haematology services within a primary care setting and has an interest in medical education, being the co-founder of Blooducation. 


  • FRCPath 2018
  • PhD, University of Birmingham 2016
  • MRCP (UK) 2009
  • MBChB (Hons) University of Birmingham 2006
  • MSc (Distinction) in pathological studies, University of Birmingham 2005


  • MBChB programme – Immunology and infection module; cancer module
  • Supervisor for intercalating BSc students


Research themes:

  • Optimising vaccination strategies and minimising infection risk in patients with CLL
  • Investigating immunity in the setting of novel therapeutic agents


Recent publications


Loke, J, Upasani, V, Gaskell, C, Fox, S, Fletcher, R, Thomas, C, Hopkins, L, Kumari, A, Tang, T, Yafai, E, Boucher, R, Homer, V, Toth, A, Chan, YLT, Randall, K, Rider, T, O'nions, J, Drew, V, Pillai, A, Dungarwalla, M, Murray, D, Khan, A, Wandroo, F, Moore, S, Krishnamurthy, P, Huang, YJ, Knapper, S, Byrne, J, Zhao, R, Craddock, C, Parry, H, Moss, P, Stanworth, SJ & Lowe, DM 2023, 'Defective T‐cell response to COVID‐19 vaccination in acute myeloid leukaemia and myelodysplastic syndromes', British Journal of Haematology, vol. 202, no. 3, pp. 498-503. https://doi.org/10.1111/bjh.18894

Barber, VS, Peckham, N, Duley, L, Francis, A, Abhishek, A, Moss, P, Cook, JA & Parry, HM 2023, 'Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia', BMJ open, vol. 13, no. 9, e077946. https://doi.org/10.1136/bmjopen-2023-077946

Parry, H, Moss, P, Stephens, C, Bentley, C, Brown, K, Amirthalingam, G, Hallis, B, Otter, A, Zuo, J & Moss, P 2022, 'Extended interval BNT162b2 vaccination enhances peak antibody generation', NPJ vaccines, vol. 7, no. 1, 14. https://doi.org/10.1038/s41541-022-00432-w

Walewska, R, Parry-Jones, N, Eyre, TA, Follows, G, Martinez-Calle, N, McCarthy, H, Parry, H, Patten, PEM, Riches, JC, Hillmen, P & Schuh, AH 2022, 'Guideline for the treatment of chronic lymphocytic leukaemia', British Journal of Haematology, vol. 197, no. 5, pp. 544-557. https://doi.org/10.1111/bjh.18075

Parry, H, McIlroy, G, Moss, P, Damery, S, Tyson, G, Logan, N, Davis, C, Willett, B, Zuo, J, Ali, M, Kaur, M, Stephens, C, Brant, D, Otter, A, McSkeane, T, Rolfe, H, Faustini, S, Richter, A, Lee, S, Wandroo, F, Shafeek, S, Pratt, G, Paneesha, S & Moss, P 2022, 'Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemia', Journal of Hematology and Oncology, vol. 15, no. 1, 3. https://doi.org/10.1186/s13045-021-01219-7

Tye, E, Jinks, E, Haigh, T, Kaul, B, Patel, P, Parry, H, Newby, M, Crispin, M, Kaur, N, Moss, P, Drennan, S, Taylor, G & Long, H 2022, 'Mutations in SARS-CoV-2 spike protein impair epitope-specific CD4+ T cell recognition', Nature Immunology, vol. 23, pp. 1726–1734. https://doi.org/10.1038/s41590-022-01351-7

Shields, AM, Venkatachalam, S, Shafeek, S, Paneesha, S, Ford, M, Sheeran, T, Kelly, M, Qureshi, I, Salhan, B, Karim, F, De Silva, N, Stones, J, Lee, S, Khawaja, J, Kaudlay, PK, Whitmill, R, Kakepoto, GN, Parry, HM, Moss, P, Faustini, SE, Richter, AG, Drayson, MT & Basu, S 2022, 'SARS-CoV-2 vaccine responses following CD20-depletion treatment in patients with haematological and rheumatological disease: a West Midlands Research Consortium study', Clinical and Experimental Immunology, vol. 207, no. 1, pp. 3-10. https://doi.org/10.1093/cei/uxab018

CHAMPION steering committee members, Constantine, A, Dimopoulos, K, Jenkins, P, Tulloh, RMR, Condliffe, R, Jansen, K, Chung, NAY, Oliver, J, Parry, H, Fitzsimmons, S, Walker, N, Wort, SJ, Papaioannou, V, von Klemperer, K & Clift, P 2022, 'Use of Pulmonary Arterial Hypertension Therapies in Patients with a Fontan Circulation: Current Practice Across the United Kingdom.', Journal of the American Heart Association, vol. 11, no. 1, e023035. https://doi.org/10.1161/jaha.121.023035

Parry, H, Bruton, R, Ayodele, R, Sylla, P, McIlroy, G, Logan, N, Scott, S, Nicol, S, Verma, K, Stephens, C, Willett, B, Zuo, J & Moss, P 2022, 'Vaccine subtype and dose interval determine immunogenicity of primary series COVID-19 vaccines in older people', Cell Reports Medicine, vol. 3, no. 9, 100739. https://doi.org/10.1016/j.xcrm.2022.100739

Parry, H, McIlroy, G, Bruton, R, Ali, M, Stephens, C, Damery, S, Otter, A, McSkeane, T, Rolfe, H, Faustini, S, Wall, N, Hillmen, P, Pratt, G, Paneesha, S, Zuo, J, Richter, A & Moss, P 2021, 'Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia', Blood Cancer Journal, vol. 11, no. 7, 136. https://doi.org/10.1038/s41408-021-00528-x


Roberts, T, Uwenedi, G, Bruton, R, McIlroy, G, Damery, S, Sylla, P, Logan, N, Scott, S, Lau, M, Elzaidi, A, Plass, S, Mallick, S, Spencer, K, Stephens, C, Bentley, C, Pratt, G, Zuo, J, Paneesha, S, Willett, B, Moss, P & Parry, H 2024, 'Enhancement of Omicron-specific immune responses following bivalent COVID-19 booster vaccination in patients with chronic lymphocytic leukaemia', Blood Cancer Journal, vol. 14, no. 1, 22. https://doi.org/10.1038/s41408-023-00940-5

Farhat, M, Croft, W, Parry, HM, Verma, K, Kinsella, FAM, Xu, J, Bone, D, McSkeane, T, Paneesha, S, Pratt, G, Moss, P & Zuo, J 2024, 'PD-1 expression contributes to functional impairment of NK cells in patients with B-CLL', Leukemia. https://doi.org/10.1038/s41375-024-02271-1

Parry, H, Moss, P, Uwenedi, G, Roberts, T, Sylla, P, Cook, J, Elzaidi, A, Lau, M, Drury, T, Bray, A, Mallick, S, Spencer, K, Bentley, C, Mcilroy, G, Scott, S, Logan, N, Zuo, J, Willett, B & Moss, P 2023, 'Robust generation of neutralising antibodies against Omicron variants following bivalent mRNA booster vaccine in elderly people aged >80 years', Journal of Infection. https://doi.org/10.1016/j.jinf.2023.08.014

Parry, H, Bruton, R, Roberts, T, Mcilroy, G, Damery, S, Sylla, P, Dowell, AC, Tut, G, Lancaster, T, Bone, D, Willett, B, Logan, N, Scott, S, Hulme, S, Jadir, A, Amin, U, Nicol, S, Stephens, C, Faustini, S, Al-taei, S, Richter, A, Blakeway, D, Verma, K, Margielewska-davies, S, Pearce, H, Pratt, G, Zuo, J, Paneesha, S & Moss, P 2022, 'COVID-19 vaccines elicit robust cellular immunity and clinical protection in chronic lymphocytic leukemia', Cancer Cell, vol. 40, no. 6, pp. 584-586. https://doi.org/10.1016/j.ccell.2022.05.001

Ebanks, D, Faustini, S, Shields, A, Parry, H, Moss, P, Plant, T, Richter, A & Drayson, M 2021, 'Cross reactivity of serological response to SARS-CoV-2 vaccination with viral variants of concern detected by lateral flow immunoassays', Journal of Infection, vol. 83, no. 4, pp. e18-e20. https://doi.org/10.1016/j.jinf.2021.07.020

View all publications in research portal


Immunocompromised immunity; vaccine responses; clinical haematologist; blood cancer

Media experience


Health policy; health management; primary care; general practice; NHS; National Health Service