Dr Jon Hazeldine BSc (Hons), MSc, PhD, AFHEA

• Associate Fellow of the Higher Education Academy, 2018.
• PhD in Immunology, University of Birmingham, 2013.
• MSc in Immunology, University of Birmingham, 2008.
• BSc (Hons) in Human Biology, University of Birmingham, 2007.

Dr Hazeldine graduated from the University of Birmingham in 2007 with a BSc (Hons) in Human Biology before undertaking an MSc in Immunology in 2008 during which he studied the effect of cyclin dependent kinase inhibitors on neutrophil lifespan. Dr Hazeldine then undertook a PhD investigating the effect of human ageing on the function of the innate immune system in the research group of Professor Janet M. Lord. Since completing his doctorate, Dr Hazeldine has taken his interest in innate immunity into the setting of major traumatic and thermal injury, where he explores the short (hours-days) and long (weeks, months and years) term effects that severe injury has on the function of the innate immune system and how this influences patient outcomes.

Via a collaboration with pre-hospital emergency care paramedics and the Midlands Air Ambulance Charity, Dr Hazeldine is currently the lead laboratory investigator of the “Golden Hour” project, a unique study that acquires blood samples from major trauma patients at the scene of their injury. Acquired within 1-hour of an emergency 999 call, the analysis of these blood samples has revealed novel insights into the immune and inflammatory response to major trauma, with evidence of systemic immune suppression detectable prior to a patients arrival to hospital.

Undergraduate

• BSc Year 2, Immunity and Infection.
• BSc Year 2, Stem Cells and Genetic Inheritance.
• BSc Year 3, The Biology of Ageing.

Postgraduate

• MSc Trauma Science – Critical Care, Torso Trauma and Burns Management.
• MSc Immunology and Immunotherapy: Inflammation and Cell Migration.
• MSci Y4, Clinical Haematology.
• MPharm: Health, Disease and Therapeutics.
• MBChB Year 2 Professional and Academic Skills.
• Experimental Design and Developing a Research Proposal
• Integrated PhD Life Sciences Research Project

During his PhD and postdoctoral studies, Dr Hazeldine has been involved in the laboratory supervision of:

• BSc students (>15)
• MSc students (7)
• PhD students (3)

Research themes

• The effect of major traumatic and thermal injury on the innate immune response.
• Mechanisms underlying injury-induced immune suppression.
• The immune and inflammatory response to thermal injury.
• How the immune and inflammatory response to severe injury influences patient outcomes (e.g. development of sepsis).

Public engagement

• Contributes to Continuing Professional Development Sessions on Human Biology run by The Prince’s Teaching Institute

Awards

• Co-author of an original research manuscript that won the A.L.Copley Best Paper Prize for papers published in the Journal of Clinical Hemorheology and Microcirculation in 2019.
• Primary author of “Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality”, which was the most downloaded original research paper across all issues of the European Journal of Endocrinology published during 2017.
• Awarded prize for best student. MSc immunology. University of Birmingham (2008)
• Received the Medawar Prize in Human Biology, which is awarded annually to the student, who having specialised in Human Biology, achieves the most outstanding performance in the final Honours examination for the degree of BSc in Human Biology (2007).