Dr Rahul Mahida MBBS, PhD, MRCP (UK), FHEA

Dr Rahul Mahida

Institute of Inflammation and Ageing
MRC Clinician Scientist
Associate Professor in Respiratory Medicine

Contact details

Institute of Inflammation and Ageing
College of Medical and Dental Sciences
University of Birmingham
B15 2TT

Dr Mahida is an Associate Professor in Respiratory Medicine within the Institute of Inflammation and Ageing. His translational research focuses on the role of inflammatory pathways and macrophage dysfunction in the pathogenesis of acute (ARDS, pneumonia) and chronic (pulmonary fibrosis) respiratory diseases. He has a particular interest in the role of extracellular vesicle-mediated immune dysfunction in these diseases, with the aim of developing novel therapeutic strategies.

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ResearchGate Profile


• Postgraduate Certificate in Higher Education, University of Birmingham (2021)
• PhD in Translational Respiratory Immunology, University of Birmingham (2020)
• Specialty Certificate in Respiratory Medicine (2017)
• MRCP (2013)
• MBBS, Newcastle University, 2010
• BSc in Medical Microbiology and Immunology (1st class), Newcastle University, 2007


Biomedical Science

1st Year - Introduction to Respiratory Medicine

Dr Mahida supervises BMedSci and MBChB intercalation projects

4th Year - Human Diseases

Respiratory Medicine MSc
Immunology and Immunotherapy MSc
Pharmacy MPharm

Other activities

Rahul is an Honorary Consultant in Respiratory and General (Internal) Medicine at the University Hospitals Birmingham NHS Foundation Trust.


Mahida RY, Price J, Lugg ST, Li H, Parekh D, Scott A, Harrison P, Matthay MA, Thickett DR. (2022) CD14 positive Extracellular Vesicles in Broncho-Alveolar Lavage Fluid as a New Biomarker of Acute Respiratory Distress Syndrome. Am J Physiol Lung Cell Mol Physiol. doi:10.1152/ajplung.00052.2022.

Mahida RY, Scott A, Parekh D, Lugg ST, Belchamber KBR, Hardy RS, Matthay MA, Naidu B, Thickett DR. (2021) Assessment of alveolar macrophage dysfunction using an in vitro model of Acute Respiratory Distress Syndrome. Front Med (Lausanne). 29;8:737859. doi: 10.3389/fmed.2021.737859.

Mahida RY, Scott A, Parekh D, Lugg ST, Hardy RS, Lavery GG, Matthay MA, Naidu B, Perkins GD, Thickett DR. (2021) Acute Respiratory Distress Syndrome is associated with impaired alveolar macrophage efferocytosis. Eur Respir J. 9;58(3):2100829. doi: 10.1183/13993003.00829-2021.

Mahida RY, Thickett DR. (2021) Management of acute on chronic respiratory failure associated with interstitial lung disease. In: Janes SM, editor. Encyclopaedia of Respiratory Medicine. 2nd ed: Elsevier

Mahida RY, Chotalia M, Alderman J, et al. (2020) Characterisation and outcomes of ARDS secondary to pneumonia in patients with and without SARS-CoV-2: a single-centre experience. BMJ Open Respir Res. 7(1):e000731.

Ross JT, Nesseler N, Leligdowicz A, Zemans RL, Mahida RY, et al. (2020) The ex vivo perfused human lung is resistant to injury by high-dose S. pneumoniae bacteremia. Am J Physiol Lung Cell Mol Physiol. 1;319(2):L218-L227.

Mahida RY, Matsumoto S, Matthay MA. (2020) Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 63(1):15-24.

Sapey E, Patel JM, Greenwood H, Walton GM, Grudzinska F, Parekh D, Mahida RY, et al. (2019) Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial. Am J Respir Crit Care Med. 200(10):1282-1293.

Lugg ST, Alridge KA, Howells PA, Parekh D, Scott A, Mahida RY et al. (2019) Dysregulated alveolar function and complications in smokers following oesophagectomy. ERJ Open Res. 4;5(1).

Parekh D, Dancer RCA, Scott A, D'Souza VK, Howells PA, MahidaRY, et al. (2018) Vitamin D to Prevent Lung Injury Following Esophagectomy-A Randomized, Placebo-Controlled Trial. Crit Care Med. 46(12):e1128-e1135.

Scott A, Lugg ST, Aldridge K, Lewis KE, Bowden A, Mahida RY, et al. (2018) Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages. Thorax. 73(12):1161-1169.

Borthwick LA, Suwara MI, Carnell SC, Green NJ, Mahida R, et al. Pseudomonas aeruginosa induced airway epithelial injury drives fibroblast activation: a mechanism in chronic lung allograft dysfunction. Am J Transplant. 16(6):1751-65.

Falconer J, Mahida R, Venkatesh D, Pearson J, Robinson JH. (2016) Unconventional T-cell recognition of an arthritogenic epitope of proteoglycan aggrecan released from degrading cartilage. Immunology. 147(4):389-98.

Dancer RC, Parekh D, Lax S, D'Souza V, Zheng S, Bassford CR, Park D, Bartis DG, Mahida R, et al. (2015) Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax. 70(7):617-24.

Greenwood H, Patel J, Mahida R, Wang Q, Parekh D, Dancer RC, et al. (2014) Simvastatin to modify neutrophil function in older patients with septic pneumonia (SNOOPI): study protocol for a randomised placebo-controlled trial. Trials. 15:332.

Mahida RY, Bowman S, Naidu B, Thickett DR. (2014) Positron emission tomography aids diagnosis of relapsing polychondritis. BMJ Case Rep.

Bartis D, Mise N, Mahida RY, Eickelberg O, Thickett DR. (2014) Epithelial–mesenchymal transition in lung development and disease: does it exist and is it important? (Review). Thorax 69(8):760-5.

Jones AL, Fisher AJ, Mahida R, Gould K, et al. (2014) Nocardia kroppenstedtii sp. nov., an actinomycete isolated from a lung transplant patient with a pulmonary infection. Int J Syst Evol Microbiol. 64(Pt 3):751-754.

Borthwick LA, Corris PA, Mahida R, et al. (2013) TNFα from classically activated macrophages accentuates epithelial to mesenchymal transition in obliterative bronchiolitis. Am J Transplant. 13(3):621-33.

Mahida R, Turner AM. (2013) MUC5B: a good target for future therapy in pulmonary fibrosis? Thorax. 68(5):401.

Mahida RY, Wiscombe S, Fisher AJ. (2012) Current status of lung transplantation. Chron Respir Dis. 9(2):131-45.

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