Professor Daniel Tennant is a Professor of Biochemistry in the Department of Metabolism and Systems Science, situated on the second floor of the Institute of Biomedical Research. He uses stable isotope tracers to investigate changes in the use of nutrients in conditions where oxygen is limiting (hypoxia), or in the presence of genetic mutations that induce a hypoxia-like response. Dan applies the fundamental knowledge gained from these research projects to understand the pathogenesis of diseases where changes in oxygenation play a role; in particular, cancer.
Dan also directs the Metabolic Tracer Analysis Core (MTAC) within the Department in order to develop novel means to analyse cellular and tissue metabolism using stable isotope tracer molecules, and collaborates with groups worldwide who are interested in using these techniques to study the metabolism of their system, or the metabolism of labelled product.
Professor Tennant publishes both primary research and reviews in high impact journals, including Nature Communications, Cell Metabolism, Nature Reviews Cancer and Cell, and is regularly asked to speak at international conferences.