Myelin associated glycoprotein (MAG) antibody

MAG reactivity
Primate sciatic nerve showing anti-MAG IgM staining the inner and outer myelin of axons (targets is a 100 kDa glycoprotein).
 

Anti-MAG (IgM) binding to the white matter sandwiched between the granular layer of the primate cerebellum.

Neurological syndrome: Peripheral neuropathy

Associated tumour: Waldenstrom's macroglobulinaemia, multiple myeloma