Yo antibody
.jpg?quality=80&height=73&width=100) |
Yo antibody (also known as Purkinje cell antibody type 1 (PCA-1)) reacts with primate cerebellum with coarse granular staining of the Purkinje cell cytoplasm. This reaction must be confirmed with Western blot/line blot.
Note: the red neuronal nuclei are due to ethidium bromide counterstain. |
Clinical indication: Cerebellar degeneration
Associated tumours: Breast and ovarian carcinomas. With only few exceptions PCA are found exclusively in female patients.