Firstly, in deciding funding priorities in these uncertain times, the instinct of government is to place increased emphasis on immediate economic impact, directly linking funding to near-term commercial potential. In fact, there has been significant uplift in overall funding for science under the current government through the Industrial Strategy Challenge Fund, which is designed to support collaborations between industry and the UK science base, aiming to address the UK's historic weakness in gaining financial benefit from its unquestioned excellence in basic science. However, tapping into these resources is not so easy if your focus is fundamental scientific questions such as Higgs bosons, gravitational waves or habitable planets orbiting stars that are light-years away.