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mcsh-collaboration

We may be in the era of Brexit, but science has no borders!

Mike Tomlinson’s lab have provided their CRISPR/Cas9 genome editing expertise to help Prof Stefan Lichtenthaler (Munich) and Dr Attila Braun (Wurzburg) publish papers in the FASEB Journal and Arteriosclerosis, Thrombosis, and Vascular Biology, respectively.  Prof Lichtenthaler’s paper reports the rapid post-lysis autocatalytic degradation of the ‘molecular scissor’ ADAM10.  Dr Braun’s paper identifies TRPM7 kinase as a novel regulator of Ca2+ signalling in platelets, and a potential drug target for the treatment of heart attack and stroke.

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Read the two papers here: