Historian Nükhet Varlık (History, Rutgers) joined us to discuss how studying the Ottoman experience of plague (from ca. 1340s to ca. 1940s – six-hundred years of uninterrupted outbreaks) invites new possibilities for rethinking the Black Death pandemic in its global context. In the paper, Professor Varlik used historical, epidemiological, and ecological approaches, to examine the transformations of Ottoman plagues in the context of larger environmental and ecological changes, especially those in the flora and fauna of the eastern Mediterranean region. The evolutionary geneticist and biological anthropologist Hendrik Polinar (Anthropology, McMaster) then provided a short response on the inter-disciplinary implications of such work.