Woman in lab coat dropping fluids into plastic containers

At present, 15 million tonnes of single-use plastic is consumed annually in the global healthcare sector, a volume roughly equivalent to half of the total plastic waste collected in the EU in 2021. However, most future strategies for healthcare provision depend on unsustainable single-use plastic products and hence, healthcare-related plastic waste is predicted to increase.1

A recent public survey in the UK revealed the public ranked medical applications of plastic as the top priority over other potential uses.2 While the NHS already has plans to reduce unnecessary plastic waste as part of ‘Delivering a Net Zero NHS’, with other healthcare systems around the world following suit, eliminating the plastic waste associated with medical testing remains a complex scientific, technical, social and economic challenge to resolve.

Medical tests take place in, and beyond, formal clinical settings. The results of these tests provide essential evidence in the diagnosis and treatment of many diseases. Point of care tests (POCTs) are widely deployed across the globe for the diagnosis of diseases such as tuberculosis, malaria, and AIDS, particularly in low- and middle-income countries (LMICs).3

Medical tests take place in, and beyond, formal clinical settings. The results of these tests provide essential evidence in the diagnosis and treatment of many diseases. Point of care tests (POCTs) are widely deployed across the globe for the diagnosis of diseases such as tuberculosis, malaria, and AIDS, particularly in low- and middle-income countries (LMICs).

Andrew Dove, Professor of Sustainable Polymer Chemistry, University of Birmingham

Medical tests take place in, and beyond, formal clinical settings. The results of these tests provide essential evidence in the diagnosis and treatment of many diseases. Point of care tests (POCTs) are widely deployed across the globe for the diagnosis of diseases such as tuberculosis, malaria, and AIDS, particularly in low- and middle-income countries (LMICs).3

The COVID-19 pandemic, however, resulted in the mass deployment of POCTs in high-income countries (HICs) and hence highlighted the challenges of circularising the resultant plastic waste.

It's not just COVID-19 POCTs that are significant, though. POCTs in high-income countries also extend to ovulation/pregnancy test kits and diabetic blood home tests. POCTs continue to contribute to a radical change in the way we deliver and engage with diagnostic medical services, which we see on a regular basis in increased virtual interactions between patients and healthcare practitioners and increasing normalisation of home testing for illness. Even though the use of COVID-19 POCTs is in decline, the threat of new pandemic viruses, ease of application as well as opportunities to extend their use suggests that there is an unmet demand for POCTs.4

Despite this need and projected growth, POCTs are not applied in a circular economy framework, leading to increased pollution from landfill or burning/incineration. Contrasting this, plastic waste generated in clinical settings is at least as significant as home testing. Despite the concentrated nature of lab-based testing, this waste is still incinerated, rather than recycled, contributing to global carbon emissions and unsustainable resource use.

Funded by UKRI EPSRC and BBSRC, my University of Birmingham team will combine cutting edge, interdisciplinary science, and engineering to create innovative, sustainable circular solutions to address these medical plastic challenges; the home and clinical environments present different scientific challenges in creating circular solution.

In theory, the clinical setting could allow for very high recovery of waste plastics. The research project will seek to understand how to clean sort and reuse plastics in a manner that is more sustainable than incineration. Given the different challenges in a home setting, the project will explore public behaviour patterns, under-developed waste recovery and disposal systems interplay. Currently, in the worst case, these plastics will be released directly into the environment, at best they will be collected for recycling but not recycled. As such, a major scientific challenge is to design plastics that can be circularised but that will also be ecologically neutral if disposal is uncontrolled.

To address these challenges, the project team will take an innovative, technology-based, interdisciplinary approach to ensure that sustainable solutions are developed for each material waste stream in a way that reflects specific economic, regulatory, social, and environmental contexts, and can be sufficiently integrated into society. The challenge is broad, but deeply necessary for our changing environment, and help us to take one more step away from a ‘throwaway’ culture towards plastics, even in medicine.

1. Lab Chip 2022, 22, 3122

2. Bespoke survey designed and carried out in partnership between University of Birmingham and YouGov Plc. Total sample size = 2942 adults. Fieldwork was under-taken between 25/03/22 – 02/04/22, carried out online. The figures have been weighted and are representative of all UK adults (aged 18+)

3. Lab Chip 2022, 22, 3122

4. Lancet 2021, 398, 1997