Vaccine rollout cut Covid deaths for cancer patients by 84%

New two year UK-wide study finds Covid-19 risk for cancer patients still higher than general population, but fell following availability of vaccinations in 2021

Young black woman wearing yellow face covering having plaster applied to vaccination site on upper right arm by doctor

Cancer patients saw a significant fall in Covid-related hospitalisations and mortality following the rollout of vaccines in the first panoramic study of its kind.

The research published in Scientific Reports today (Tuesday 25 July) looked at the impact of the global pandemic on case-outcome rates for cancer patients across a 21-month period from November 2020 to August 2022. The team of researchers led by the University of Birmingham found that hospitalisations in the period fell from nearly one in three patients (30.58%) to one in 13 patients (7.45%); and, case-mortality rates fell from more than one in five patients (20.53%) to less than one in 30 patients (3.25%).

Among cancer patients, the study also found that age was a greater predictor of mortality rates than the type of cancer that a patient had. In 2022, case-mortality rate for patients over 80 was more than one in ten (10.32%) compared to less than one in 35 (2.83%) for under 80s.

Compared to the general population, Covid-19 infections leave cancer patients more than twice as likely to be hospitalised (2.1 times as likely) or sadly die (2.54 times as likely) at the end of the study period.

Dr Lennard Lee from the Institute of Cancer and Genomic Sciences at the University of Birmingham and lead author of the study said:

"People living with cancer are worried that they have been forgotten. Our work shows that the UK is emerging out of the tunnel of the global pandemic, and we know who are still at the greatest risk of the consequences of Covid-19 infection so that they're not left behind.

“These data are undoubtedly good news for cancer patients, but despite significant falls in hospitalisations and mortality over the years we studied we can still see the additional risk that Covid-19 poses for these patients."

Thomas Starkey, PhD researcher from the University of Birmingham and first author of the study said:

"By collating and analysing electronic healthcare data for evaluating the real-world impact of the global pandemic in the UK, we can now use population-scale data to protect people living with cancer from infectious diseases such as COVID-19."

The study drew from data from the UKCCP, one of the United Kingdom’s longest running pandemic responses with a mission to safeguard, evaluate and protect patients with cancer, (www.ukcovidcancerprogramme.org).

This project was a population-based study of COVID-19 outcomes in patients with cancer from the study period of 1st November 2020 to 31st August 2022, initiated to define the disease phenotype in the highest clinical risk groups.

Notes for editors

  • For media enquiries please contact Tim Mayo, Press Office, University of Birmingham, tel: +44 (0)7920 405040:.
  • The University of Birmingham is ranked amongst the world’s top 100 institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 6,500 international students from over 150 countries.
  • The University of Birmingham is a founding member of Birmingham Health Partners (BHP), a strategic alliance which transcends organisational boundaries to rapidly translate healthcare research findings into new diagnostics, drugs and devices for patients. Birmingham Health Partners is a strategic alliance between seven organisations who collaborate to bring healthcare innovations through to clinical application:
    • University of Birmingham
    • University Hospitals Birmingham NHS Foundation Trust
    • Birmingham Women's and Children's Hospitals NHS Foundation Trust
    • Aston University
    • The Royal Orthopaedic Hospital NHS Foundation Trust
    • Sandwell and West Birmingham Hospitals NHS Trust
    • West Midlands Academic Health Science Network
    • Birmingham and Solihull Mental Health NHS Foundation Trust