Collaboration aimed at advancing automation techniques for regulatory science research

Beckman Coulter has entered into a technology collaboration with scientists at the University of Birmingham, UK, establishing a collaboration to accelerate research into higher-throughput biology to support the University’s activities towards better protecting environment and human health.

This technology collaboration will focus on developing novel strategies to integrate Beckman Coulter’s world-leading automation platforms into OMICS workflows including genomics – by improving sample preparation for transcriptome profiling and DNA population sequencing on Next Generation Sequencing (NGS) platforms – and metabolomics, focusing on increasing sample throughput in both environmental and clinical mass spectrometry metabolomics studies.

Technological innovations resulting from this collaboration specifically target the safety and management of chemicals and nanoparticles in drinking water quality, human health and ecosystems, by transforming evaluation methods that require massive numbers of samples.

‘By industrializing the process of acquiring knowledge on how gene interactions and animal metabolism are disrupted by the tens of thousands of human-made compounds that can enter the environment, we hope to provide useful and predictive toxicological information to industry and policy makers for effective environment and health protection’, said Professor John Colbourne, University of Birmingham’s Chair of Environmental Genomics.

Other applications from this collaboration are expected to include early warning systems for infectious diseases and more rapid clinical diagnoses.

The collaborative activities are expected to include engaging in joint research projects, sharing samples and data that could lead to the development of higher-throughput technologies, exchanging know-how for improving hardware and software performance, promoting the training of graduate students, and publishing new methodology and scientific advances.

“The University of Birmingham scientists are at the cutting-edge of genomics and metabolomics research in the environmental, microbial and clinical sciences and are therefore an ideal team for Beckman Coulter to partner with to develop a variety of automation solutions for high-throughput omics biology” said Julie Moore, Director of the automation and genomics business unit in Beckman Coulter's Life Sciences Division.

‘The Beckman Coulter scientists share our vision to make ultra-high-throughput sample handling and preparation a reality’, said Professor Mark Viant, Chair of Metabolomics at the University of Birmingham. He adds ‘this is going to enable us to address challenges that previously have not been feasible in omics biology.’

‘We are excited to form a technology collaboration with Beckman Coulter’ said Professor Malcolm Press, the University of Birmingham’s Pro-Vice-Chancellor for Research and Knowledge Transfer. ‘We anticipate that this program of innovative research will translate directly into improved technologies for healthcare and environmental diagnostics.’

1. About Beckman Coulter

Beckman Coulter Life Sciences’ global leadership and world-class service and support delivers instrument systems, reagents and services to improve workflow and outcomes for researchers in academic and commercial life sciences laboratories, enabling discoveries in biology-based research and development, and solutions for bioprocessing. A leader in centrifugation and flow cytometry, Beckman Coulter also has brought to market innovations in capillary electrophoresis, particle characterization and laboratory automation. Its products are used to further important areas of scientific investigation, including genomics and proteomics. For more information, please visit www.BeckmanCoulter.com.

Beckman Coulter and Biomek are trademarks of Beckman Coulter, Inc. and are registered in the USPTO.

2. About the University of Birmingham

  • The University of Birmingham is a truly global university producing world-leading research and is ranked amongst the world’s top 100 institutions. Birmingham benefits from mutual partnerships with a wide range of international institutions and hosts a large international community of researchers and students.
  • With almost 5,000 international students from more than 150 countries, and 31% of academic staff from overseas, Birmingham’s campus is truly a diverse and global place which attracts the brightest and best international students and staff.
  • The University of Birmingham has been named The Times and The Sunday Times University of the Year 2013/4.

3. This technology collaboration builds upon the rapid expansion of the environmental omics research program at the University of Birmingham, in particular contributing to the newly launched Joint Centre for Environmental Omics (JCEO), a collaboration between the University and BGI, the world’s largest genome research institute. The JCEO will seek to protect environment, health and global biodiversity by analysing the toxicity of chemical and nanomaterials more efficiently than has been achieved before. Located on the University’s Edgbaston campus, the JCEO will specialise in automated ultra-high-throughput sample processing in a facility jointly operated with the BGI and the China National GeneBank (CNGB).

For further information
Kate Chapple, Press Office, University of Birmingham, tel +44 (0)121 414 2772 or +44 (0)7789 921164, email: k.h.chapple@bham.ac.uk

Dana Walker, Global Marketing, Beckman Coulter Life Sciences tel: +1 317.295.3719
email: dcwalker@beckman.com