Health effects from pollutants typically take decades to be identified, and often rely on large groups having similar exposures to a specific pollutant over extended timescales, such as those occurring within worker populations. Thus, occupational exposure is the most common route for identifying health effects, for example, in miners (asbestos-related issues), in hairdressers (dye- and other chemical-related issues), in bar workers (passive smoking effects etc,), and typically works backwards from an identified health effect to identify the specific cause. However, with the rapid pace of commercialisation of nanoscale materials (faster than regulation can keep pace), and the explosion in public awareness of micro- and nano-plastics where even remote arctic areas are affected, there is a need for new, precautionary and responsibility based approaches to assess potential long-term health implications of sustained exposure to nano-enabled consumer products, which nowadays starts in earliest childhood.