Dr Pawel Grzechnik was awarded a grant from the US Charity Foundation for Prader-Willi Research. Prader-Willi Syndrome is a rare genetic condition with no cure, which causes physical disabilities, learning difficulties and behavioural problems. Pawel and the funded postdoc will investigate how unusual non-coding RNAs, transcribed from the Prader-Willi locus, regulate transcription in induced pluripotent stem (iPS) cells, and how lack of these RNAs affects differentiation to neurons. Pawel will collaborate with Dr Paloma Garcia, from the Institute of Cancer and Genomic Sciences in MDS, on the iPS cell aspects of the work.