Congratulations Jan Kreft on his PNAS opinion paper arguing that individual-based models are ideal for incorporating the intra-cellular dynamics of synthetic organisms in order to predict their behaviour and fitness under various conditions.
The paper was published on 5 Nov 2013 and can be read here http://dx.doi.org/10.1073/pnas.1317472110
Kreft JU, Plugge CM, Grimm V, Prats C, Leveau JHJ, Banitz T, Baines S, Clark J, Ros A, Klapper I, Topping CJ, Field AJ, Schuler A, Litchman E, Hellweger FL (2013). Mighty small: Observing and modeling individual microbes becomes big science. PNAS 110: 18027-18028