Publications

Key publications from the NIHR RIGHT-Leprosy study group.

TABLE trial

Protocol paper: Napit, I.B., Shrestha, D., Bishop, J. et al. An individual randomised efficacy trial of autologous blood products, leukocyte and platelet-rich fibrin (L-PRF), to promote ulcer healing in leprosy in Nepal: the TABLE trial protocol. Trials 22, 453 (2021). https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05392-5

Systematic review: Napit IB, Shrestha D, Neupane K, et al Autologous blood products: Leucocyte and Platelets Rich Fibrin (L-PRF) and Platelets Rich Plasma (PRP) gel to promote cutaneous ulcer healing – a systematic review. BMJ Open 2023;13:e073209. doi: 10.1136/bmjopen-2023-073209. https://bmjopen.bmj.com/content/13/12/e073209

Main trial paper: Napit IB, Shrestha D, Choudhury S, Gkini E, Ilozumba O, Gill P, Bishop J, Neupane K, Adhikari A, Sartori J, Watson SI, Lilford R. A randomised Trial of Autologous Blood products, leukocyte and platelet-rich fibrin (L-PRF), to promote ulcer healing in LEprosy: The TABLE trial. PLoS Negl Trop Dis. 2024 May 2;18(5):e0012088. doi: 10.1371/journal.pntd.0012088. PMID: 38696527; PMCID: PMC11093377. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093377/

Methodology paper: Watson SI, Gkini E, Bishop J, Scandrett K, Napit I, Lilford RJ. Modelling wound area in studies of wound healing interventions. BMC Med Res Methodol. 2024 Sep 16;24(1):206. doi: 10.1186/s12874-024-02326-y. PMID: 39285279; PMCID: PMC11403831. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403831/

Quality of Life paper: Gibbs NK, Ochalek J, Napit IB, Shrestha D, Goncalves PS, Lilford RJ, Sculpher M. Health-related quality of life implications of plantar ulcers resulting from neuropathic damage caused by leprosy: An analysis from the trial of autologous blood products (TABLE trial) in Nepal. PloS one. 2025 Feb 11;20(2):e0315944. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0315944

INSTIL studies

Nepal

Protocol paper: Shrestha D, Napit IB, Ansari S, Choudhury SM, Dhungana B, Gill P, Griffiths F, Gwyther H, Hagge D, Kandel S, Puri S, Sartori J, Watson SI, Lilford R. Evaluation of a self-help intervention to promote the health and wellbeing of marginalised people including those living with leprosy in Nepal: a prospective, observational, cluster-based, cohort study with controls. BMC Public Health. 2021 May 6;21(1):873. doi: 10.1186/s12889-021-10847-0. PMID: 33957899; PMCID: PMC8101219. https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-021-10847-0

India

Protocol paper: Darlong J, Govindasamy K, Ilozumba O, Choudhury S, Shrivastva A, Griffiths F, Watson S, Sartori J, Lilford R. An evaluation protocol of ‘Replicability Model’ project for detection and treatment of leprosy and related disability in Chhattisgarh, India. Plos one. 2023 Oct 18;18(10):e0275763. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0275763

Systematic review: Govindasamy K, Darlong J, Watson SI, Gill P. Prevalence of plantar ulcer and its risk factors in leprosy: a systematic review and meta-analysis. Journal of Foot and Ankle Research. 2023 Nov 13;16(1):77. https://link.springer.com/article/10.1186/s13047-023-00674-4

Sustainability

Protocol paper: Choudhury S, Ilozumba O, Darlong J, et al. Investigating the sustainability of self-help programmes in the context of leprosy and the work of leprosy missions in Nigeria, Nepal and India: a qualitative study protocol. BMJ Open 2023;13:e070604. doi:10.1136/bmjopen-2022-070604 https://bmjopen.bmj.com/content/13/5/e070604

HELP trial

Protocol: Udo S, Ogbu Sunday P, Tsaku PA, Oladejo IO, Meka A, Ugwu LC, Ajisola M, Akinyemi J, Oladejo A, Omigbodun A, Choudhury SM, Sartori J, Ilozumba O, Watson S, Lilford R. Raw, Unadulterated African Honey for Ulcer Healing in Leprosy: Protocol for the Honey Experiment on Leprosy Ulcer (HELP) Randomized Controlled Trial. JMIRx Med. 2024 Mar 1;5:e50970. doi: 10.2196/50970. PMID: 38488451; PMCID: PMC11024902. https://pmc.ncbi.nlm.nih.gov/articles/PMC11024902/

Health economics

Ochalek, J., Gibbs, N.K., Faria, R., Darlong, J., Govindasamy, K., Harden, M., Meka, A., Shrestha, D., Napit, I.B., Lilford, R.J. and Sculpher, M., 2023. Economic evaluation of self-help group interventions for health in LMICs: a scoping review. Health Policy and Planning, p.czad060. https://academic.oup.com/heapol/advance-article/doi/10.1093/heapol/czad060/7246518

Self-care Guidelines for people affected by leprosy

Richard J. Lilford; Self-care for people affected by leprosy; Leprosy Review; 2021; 92; 4; 314-316; DOI: 10.47276/lr.92.4.3142.

Onaedo Ilozumba, Richard J. Lilford; Self-care programmes for people living with leprosy: a scoping review; Leprosy Review; 2021; 92; 4; 317-337; DOI: 10.47276/lr.92.4.3173.

Bahadir Celiktemur, Sopna Mannan Choudhury, Richard Lilford; Organizing and managing a programme for self-care in leprosy; Leprosy Review; 2021; 92; 4; 338-343; DOI: 10.47276/lr.92.4.3384.

Sopna Mannan Choudhury, Laura Kudrna, Bahadir Celiktemur, Richard James Lilford; Application of behavioural psychology principles to self-care programmes for people living with leprosy; Leprosy Review; 2021; 92; 4; 344-355; DOI: 10.47276/lr.92.4.3445.

Joydeepa Darlong; Self-care in leprosy at the front line; Leprosy Review; 2021; 92; 4; 356-365; DOI: 10.47276/lr.92.4.3566.

Karthikeyan Govindasamy, Sathish Kumar Paul; Appropriate footwear and orthoses are essential components in the management of the foot at risk of ulceration in leprosy; Leprosy Review; 2021; 92; 4; 366-374; DOI: 10.47276/lr.92.4.3667.

Linda Lehman; Personal experience with self-care training in different settings; Leprosy Review; 2021; 92; 4; 375-378; DOI: 10.47276/lr.92.4.3758.

Sopna Mannan Choudhury; Experience in receiving and practicing self-care as a person affected by leprosy; Leprosy Review; 2021; 92; 4; 379-384; DOI: 10.47276/lr.92.4.379