Dr Olalekan Lee Aiyegbusi MBChB, PhD

Dr Olalekan Lee Aiyegbusi

Institute of Applied Health Research
Associate Professor

Contact details

Centre for Patient-Reported Outcome Research (CPROR)
Murray Learning Centre
University of Birmingham
B15 2TT

Lee is an Associate Professor and Deputy Director, at the Centre for Patient-Reported Outcome Research (CPROR), Institute of Applied Health Research. His research focuses on the optimisation of patient-reported outcomes (PRO) assessments for clinical research, routine clinical practice, and regulatory purposes.

Lee is a Co-Lead for the PRO theme of the NIHR Biomedical Research Centre BirminghamApplied Research Collaboration West Midlands. He is also the Co-Lead for the PRO theme of the MRC-Trial Methodology Research Partnership (TMRP) Outcomes working group.

Lee is the Patient and Public Involvement and Engagement (PPIE) Lead for 3 projects. He is Principal Investigator and a co-investigator for over 25 grants with a total grant income of more than £8.8 million. He has over published over 100 articles with several first author publications in The Lancet, Nature Medicine, Nature Reviews Drug Discovery, Journal of the Royal Society of Medicine, and Nature Communications.

Lee has received several invitations as guest speaker and subject expert including an invitation to a roundtable to discuss Long COVID which was convened by the office of the Chief Science Advisor Task Force in Canada. He is currently a Guest Editor for Journal of Patient-Reported Outcomes (JPRO) curating a special issue on PPIE.


  • Fellow of the Higher Education Academy (FHEA), UK 2022
  • Postgraduate Certificate in Higher Education (PGCHE), University of Birmingham, UK 2022
  • Doctor of Philosophy (PhD), University of Birmingham, 2019
  • Masters in Public Health (MPH), University of Birmingham, 2014
  • Masters in Business Administration (MBA), University of Cardiff, 2009
  • Medicine (MBChB), Obafemi Awolowo University, Nigeria, 2007


Lee is currently a tutor on the Selection, Collection and Reporting of Outcomes Module of the MSc Clinical Trials programme. He serves as a small group tutor on Year 1 and 2, undergraduate MBChB modules within the College of Medical and Dental Sciences. In addition, he supervises undergraduate MBChB projects (HIER & PIP) and PhD students. Lee is a supervisor and marker for the MPH dissertation, and a personal academic tutor (PAT) for the MPH programme. He is the MDS Representative on the Higher Education Futures institute (HEFi) Board of Examiners.

Other activities


Recent publications


the PC-COS Children Study Group, Seylanova, N, Chernyavskaya, A, Degtyareva, N, Mursalova, A, Ajam, A, Xiao, L, Aktulaeva, K, Roshchin, P, Bobkova, P, Aiyegbusi, OL, Anbu, AT, Apfelbacher, C, Asadi-Pooya, AA, Ashkenazi-Hoffnung, L, Brackel, C, Buonsenso, D, De Groote, W, Diaz, JV, Dona, D, Galvin, AD, Genuneit, J, Goss, H, Hughes, SE, Jones, CJ, Kuppalli, K, Malone, LA, Mcfarland, S, Needham, DM, Nekliudov, N, Nicholson, TR, Oliveira, CR, Schiess, N, Segal, TY, Sigfrid, L, Thorne, C, Vijverberg, S, Warner, JO, Were, WM, Williamson, PR & Munblit, D 2024, 'Core Outcome Measurement Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID) in Children and Young People: An International Delphi Consensus Study “PC-COS Children”', European Respiratory Journal. https://doi.org/10.1183/13993003.01761-2023

McMullan, C, Haroon, S, Turner, G, Aiyegbusi, OL, Subramanian, A, Hughes, SE, Flanagan, S, Nirantharakumar, K, Davies, EH, Frost, C, Jackson, L, Guan, N, Alder, Y, Chong, A, Buckland, L, Jeyes, F, Stanton, D & Calvert, M 2024, 'Key considerations for digital decentralised clinical trials from a feasibility study assessing pacing interventions for Long COVID', Scientific Reports.

Phillips, T, Aiyegbusi, OL, Cockwell, P, Wheeler, DC, Kalra, PA, Taal, MW & Fraser, S 2024, 'Potentially modifiable factors associated with health-related quality of life among people with chronic kidney disease: baseline findings from the National Unified Renal Translational Research Enterprise CKD (NURTuRE-CKD) cohort', Clinical Kidney Journal. https://doi.org/10.1093/ckj/sfae010

Hughes, SE, McMullan, C, Aiyegbusi, OL, Shaw, K, Kinsella, F, Ferguson, P, Khatsuria, F, Burns, D, Pyatt, L, Ansell, J, Chakera, E, Richardson-Abraham, J, Denniston, AK, Davies, EH, Craddock, C & Calvert, M 2024, 'Protocol for a mixed-methods study to develop and feasibility test a digital system for the capture of Patient-Reported Outcomes (PROs) in patients receiving Chimeric Antigen Receptor T-cell (CAR-T) therapies (The PRO-CAR-T Study)', BMJ open, vol. 14, no. 3, e085392. https://doi.org/10.1136/bmjopen-2024-085392

Aiyegbusi, OL, Cruz Rivera, S, Roydhouse, J, Kamudoni, P, Alder, Y, Anderson, N, Baldwin, RM, Bhatnagar, V, Black, J, Bottomley, A, Brundage, M, Cella, D, Collis, P, Davies, E-H, Denniston, AK, Efficace, F, Gardner, A, Gnanasakthy, A, Golub, RM, Hughes, SE, Jeyes, F, Kern, S, King-Kallimanis, BL, Martin, A, Mcmullan, C, Mercieca-Bebber, R, Monteiro, J, Peipert, JD, Quijano-Campos, JC, Quinten, C, Rantell, KR, Regnault, A, Sasseville, M, Schougaard, LMV, Sherafat-Kazemzadeh, R, Snyder, C, Stover, AM, Verdi, R, Wilson, R & Calvert, MJ 2024, 'Recommendations to address respondent burden associated with patient-reported outcome assessment', Nature Medicine. https://doi.org/10.1038/s41591-024-02827-9

Litchfield, I, Calvert, MJ, Kinsella, F, Sungum, N & Aiyegbusi, OL 2023, '"I just wanted to speak to someone - and there was no one...”: using Burden of Treatment Theory to understand the impact of a novel ATMP on early recipients', Orphanet Journal of Rare Diseases, vol. 18, no. 1, 86. https://doi.org/10.1186/s13023-023-02680-y

Maes, D, McMullan, C, Aiyegbusi, OL & Ford, S 2023, 'Clinician survey of current global practice for sarcoma surveillance following resection of primary retroperitoneal, abdominal, and pelvic sarcoma', European Journal of Surgical Oncology (EJSO). https://doi.org/10.1016/j.ejso.2023.107085

Turner, G, McMullan, C, Aiyegbusi, OL, Hughes, S, Walker, A, Jeyes, F, Adler, Y, Chong, A, Buckland, L, Stanton, DE, Davies, EH, Haroon, S & Calvert, M 2023, 'Co-production of a feasibility trial of pacing interventions for Long COVID', Research Involvement & Engagement, vol. 9, no. 1, 18. https://doi.org/10.1186/s40900-023-00429-2


Taylor, S, Law, K, Coomber‑Moore, J, Davies, M, Thistlethwaite, F, Calvert, M, Aiyegbusi, O & Yorke, J 2024, 'Correction: Patient‑reported outcome (PRO) instruments used in patients undergoing adoptive cell therapy (ACT) for the treatment of cancer: a systematic review', Systematic Reviews, vol. 13, no. 1, 117. https://doi.org/10.1186/s13643-024-02540-1

Aiyegbusi, OL & Fenton, A 2024, 'The impact of rare kidney diseases on kidney failure', The Lancet, vol. 403, no. 10433, pp. 1211-1213. https://doi.org/10.1016/S0140-6736(24)00198-3

Review article

Khatsuria, F, McMullan, C, Aiyegbusi, OL, Shaw, KL, Iqbal, R, Kinsella, F, Wilson, K, Pyatt, L, Lewis, M, Weldon, SMR, Burns, D, Chakraverty, R, Calvert, M & Hughes, S 2024, 'Development of a conceptual framework for an electronic patient-reported outcome (ePRO) system measuring symptoms and impacts of CAR-T cellular therapies in patients with haematological malignancies: A rapid review', The Lancet Oncology.

Sakthivel, P, Mostafa, A & Aiyegbusi, OL 2024, 'Factors that influence the selection of conservative management for end stage renal disease – a systematic review', Clinical Kidney Journal, vol. 17, no. 1, sfad269. https://doi.org/10.1093/ckj/sfad269

Hughes, SE, Aiyegbusi, OL, McMullan, C, Turner, GM, Anderson, N, Cruz Rivera, S, Collis, P, Glasby, J, Lasserson, D & Calvert, M 2024, 'Patient-reported outcomes in integrated health and social care: A scoping review', JRSM Open, vol. 15, no. 3, pp. 1-9. https://doi.org/10.1177/20542704241232866

Aiyegbusi, OL 2023, 'COVID-19 related headaches: epidemiology, pathophysiology, impacts, and management', Current opinion in neurology. https://doi.org/10.1097/WCO.0000000000001219

Aiyegbusi, OL, McMullan, C, Hughes, SE, Turner, GM, Subramanian, A, Hotham, R, Davies, EH, Frost, C, Alder, Y, Agyen, L, Buckland, L, Camaradou, J, Chong, A, Jeyes, F, Kumar, S, Matthews, KL, Moore, P, Ormerod, J, Price, G, Saint-Cricq, M, Stanton, D, Walker, A, Haroon, S, Denniston, AK, Calvert, MJ, Brown, K, Singh Chandan, J, Gkoutos, GV, Jackson, LJ, Lord, JM, Marshall, T, Marwaha, S, Myles, P, Nirantharakumar, K, Rivera, SC, Sapey, E, Simms-Williams, N, Williams, T & Wraith, DC 2023, 'Considerations for patient and public involvement and engagement in health research', Nature Medicine, vol. 29, no. 8, pp. 1922-1929. https://doi.org/10.1038/s41591-023-02445-x

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