Dr Kayleigh Griffiths BSc (Hons), MRes, PhD

Dr Kayleigh Griffiths

Institute of Cardiovascular Sciences
Post-Doctoral researcher

Contact details

University of Birmingham
B15 2TT

Dr Kayleigh Griffiths is a British Heart Foundation postdoctoral associate within the Cardiovascular Translational Research Group “Myocardial Infarction and Heart Failure”, at the Institute of Cardiovascular Sciences. Kayleigh’s current research project concentrates on the protective effects of nitrite during myocardial ischaemia reperfusion injury, which is under the guidance of Professor Melanie Madhani.


  • PhD Medicine, Queen’s University Belfast, UK, 2017
  • MRes Cardiovascular Health and Disease, University of Manchester, UK, 2012
  • BSc (Hons) Pharmacology, University of Manchester, UK, 2011


Dr Kayleigh Griffiths completed her undergraduate degree in Pharmacology in 2011, before moving on to complete a Masters in Cardiovascular health and disease in 2012, both at the University of Manchester, UK.

In 2017, Kayleigh completed her PhD at Queen’s University Belfast, focussing on the effects of serum amyloid A and lymphocyte activation gene 3 in cardiovascular disease and diabetes.

After her PhD, Kayleigh continued working as a researcher at Queen’s University where she was involved in two studies, PRIME STUDY (A Longitudinal Investigation of Periodontal Disease as a Risk Factor for Coronary Heart Disease and Stroke) and NICOLA (Northern Ireland cohort of longitudinal aging).

In 2018, Kayleigh joined the University of Birmingham as a Post-doctoral researcher in the Institute of Cardiovascular Sciences. Kayleigh works under the supervision of Professor Melanie Madhani in the translational research group. This group aims to assess novel pharmacological strategies to protect the heart against ischaemia reperfusion injury and heart failure.

Kayleigh is part of the committee aimed at delivering the BHF Accelerator Award given to the University of Birmingham.


Kayleigh’s current research focusses on assessing the cardioprotective role of nitrite during ischaemia reperfusion injury.

Research Groups and Centres

Cardiovascular Translational Group: Myocardial Infarction and Heart Failure

Other activities

  • Young Investigator Committee Member for the BHF Accelerator Award University of Birmingham – 2019-2021
  • Member of The British Society for Cardiovascular research 2018 – present
  • Member of International Society for Heart Research 2018 – present


Feelisch M, Akaike  T, Griffiths K, Ida T, Prysyahna O, Goodwin J.J, Gollop N.D, Fernandez B.O, Minnion M, Cortese-Krott M.M, Borgognone A, Hayes R.M, EatonP, Frenneaux M.P, Madhani M. Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides and oxidation of protein kinase G 1α redox signalling. Cardiovascular Research. July 31 2019.

Griffiths K, Maxwell A.P, McCarter R.V, Nicol P, Hogg R.E, Harbinson M, McKay G.J. Serum amyloid A levels are associated with polymorphic variants in the serum amyloid A 1 and 2 genes. Ir J Med Sci. Mar 9 2019.

Griffiths K, Pazderska A, Ahmed M, McGowan A, Maxwell AP, McEneny J, Gibney J, McKay GJ. Type 2 Diabetes in Young Females Results in Increased Serum Amyloid A and Changes to Features of High Density Lipoproteins in Both HDL2 and HDL3. J Diabetes Res. 2017;2017:1314864.  May 9.

View all publications in research portal