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Perez-Toledo, M, Beristain-Covarrubias, N, Pillaye, J, Persaud, R, Marcial Juarez, E, Jossi, S, Hitchcock, J, Alshayea, A, Channell, W, Wiersma, N, Lamerton, R, Kavanagh, D, Carestia, A, Horsnell, W, Henderson, IR, Mackman, N, Clark, AR, Jenne, CN, Rayes, J, Watson, S & Cunningham, A 2025, 'Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection', Nature Communications, vol. 16, 2356. https://doi.org/10.1038/s41467-025-57466-6
El-awaisi, J, Kavanagh, D, Heising, S, Maria Schiessl, I, Cleary, S, Hodson, D & Kalia, N 2025, 'Impact of chronic hyperglycaemia on the coronary microcirculation - benefits of targeting IL-36 and diet reversal', Basic research in cardiology. https://doi.org/1007/s00395-025-01107-y
Stapley, RJ, Sawkulycz, X, Da Mota Araujo, GHM, Englert, M, Garcia-Quintanilla, L, Smith, SRM, Ahmed, A, Haining, EJ, Kaur, N, Bacon, A, Pisarev, AV, Poulter, NS, Kavanagh, DPJ, Thomas, SG, Montague, SJ, Rayes, J, Nagy, Z & Morgan, NV 2025, 'Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression', Journal of Clinical Investigation. https://doi.org/10.1172/JCI189100
El-awaisi, J, Perrella, G, Mayer, N, Tinkova, V, Simon, CJ, Grygielska, B, Watson, SP, Dimitrov, JD, Brill, A, Hassan, E, Nicolson, PLR, Kavanagh, D, Kalia, N & Rayes, J 2025, 'Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in an organ-specific manner in sickle cell mice', Arteriosclerosis Thrombosis and Vascular Biology. https://doi.org/10.1161/ATVBAHA.124.32207
Sun, J, Rojo Cortes, F, Benitez, S, Forero, MG, Li, G, Singh, D, Wang, X, Cachero, S, Moreira, M, Kavanagh, D, Jefferis, G, Croset, V & Hidalgo, A 2024, 'A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit', eLife, vol. 13, RP102222. https://doi.org/10.7554/eLife.102222.2
Bourne, JH, Perrella, G, El-Awaisi, J, Terry, LV, Tinkova, V, Hogg, RL, Gant, P, Grygielska, B, Kalia, N, Kavanagh, D, Brill, A, Dimitrov, JD, Watson, SP & Rayes, J 2024, 'Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice', Journal of Thrombosis and Haemostasis, vol. 22, no. 7, pp. 2018-2026. https://doi.org/10.1016/j.jtha.2024.04.008
El-Awaisi, J, Kavanagh, DPJ & Kalia, N 2024, 'Monitoring coronary blood flow by laser speckle contrast imaging after myocardial ischaemia reperfusion injury in adult and aged mice', Frontiers in cardiovascular medicine, vol. 11, 1358472. https://doi.org/10.3389/fcvm.2024.1358472
Hopkin, SJ, Pezhman, L, Begum, J, Kavanagh, D, McGettrick, HM, Iqbal, AJ & Chimen, M 2023, 'Aging modulates homeostatic leukocyte trafficking to the peritoneal cavity in a sex-specific manner', Journal of Leukocyte Biology, pp. 1-14. https://doi.org/10.1093/jleuko/qiad053
Alenazy, FO, Harbi, MH, Kavanagh, DP, Price, J, Brady, P, Hargreaves, O, Harrison, P, Slater, A, Tiwari, A, Nicolson, PLR, Connolly, DL, Kirchhof, P, Kalia, N, Jandrot-Perrus, M, Mangin, PH, Watson, SP & Thomas, MR 2023, 'Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy', Journal of thrombosis and haemostasis : JTH, vol. 21, no. 11, pp. 3236-3251. https://doi.org/10.1016/j.jtha.2023.07.018
Bumroongthai, K, Kavanagh, DPJ, Genever, P & Kalia, N 2023, 'Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin', Frontiers in immunology, vol. 14, 1257497. https://doi.org/10.3389/fimmu.2023.1257497
El-awaisi, J, Kavanagh, D, Rink, M, Weston, C, Drury, N & Kalia, N 2022, 'Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/ reperfusion injury in mice: ageing and the coronary microcirculation ', JCI Insight, vol. 7, no. 5, e155236. https://doi.org/10.1172/jci.insight.155236
Haining, E, Lowe, K, Wichaiyo, S, Kataru, RP, Nagy, Z, Kavanagh, D, Lax, S, Di, Y, Nieswandt, B, Ho-Tin-Noé, B, Mehrara, BJ, Senis, Y, Rayes, J & Watson, S 2021, 'Lymphatic blood filling in CLEC-2-deficient mouse models', Platelets, vol. 32, no. 3, pp. 352-367. https://doi.org/10.1080/09537104.2020.1734784
Campos, J, Ponomaryov, T, De Prendergast, A, Whitworth, K, Smith, C, Khan, A, Kavanagh, D & Brill, A 2021, 'Neutrophil extracellular traps and inflammasomes cooperatively promote venous thrombosis in mice', Blood Advances, vol. 5, no. 9, pp. 2319–2324. https://doi.org/10.1182/bloodadvances.2020003377
Abstract
El-awaisi, J, Kavanagh, D, Rink, M, Weston, C, Drury, N & Kalia, N 2022, 'Intravital & laser speckle investigations of the role of interleukin-36 in myocardial ischaemia reperfusion injury – a new therapeutic target for the aged heart', Journal of Molecular and Cellular Cardiology, vol. 173, no. supplement, pp. 7. https://doi.org/10.1016/j.yjmcc.2022.08.017
El-awaisi, J, Kavanagh, D & Kalia, N 2021, 'BS13 Intravital investigations of the role of IL-36 in mediating age and gender specific changes in the injured beating coronary microcirculation', Heart, vol. 107, no. Suppl 1, A162. https://doi.org/10.1136/heartjnl-2021-BCS.211
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