Recent publications
Article
O’Callaghan, E, Shields, AM, Chang, L, Umpierrez, M, Newton, D, Burns, SO, Richter, AG, Doody, G & Savic, S 2026, 'BAFF-R Expression as a Potential Biomarker Associated with COVID-19 Vaccine Non-Responsiveness in Antibody-Deficient Patients', Clinical & Experimental Immunology. https://doi.org/10.1093/cei/uxag004
Gharahdaghi, N, Faustini, SE, Shields, A, Richter, A & Uhlig, HH 2026, 'Interleukin-10 Autoantibodies and HLA-DRB1*01:03 in Inflammatory Bowel Disease', The New England Journal of Medicine, vol. 394, no. 22, pp. 2212-2222. https://doi.org/10.1056/NEJMoa2513654
Lowe, DM, Shields, AM, Richter, AG, Ashmore, E, PANORAMIC Trial Collaborative Group & PANORAMIC Trial Virology Group 2026, 'Nirmatrelvir–ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022–23: virological and immunological results of an open-label randomised trial (PANORAMIC)', The Lancet Microbe, vol. 7, no. 5, 101360. https://doi.org/10.1016/j.lanmic.2026.101360
OptiVaNTS consortium, Perez-Toledo, M, Aksu Istil, K, Marcial Juarez, E, Persaud, RR, Alshayea, A, Jossi, SE, Carestia, A, von Meijenfeld, F, Botto, M, James, LC, Surewaard, B, Afzal, Z, Shields, AM, Horsnell, WG, Lopez-Macias, C, Henderson, IR, Jenne, CN & Cunningham, AF 2026, 'Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages', mBio. https://doi.org/10.1128/mbio.02846-25
Cook, JA, Patten, PEM, Peckham, N, Moss, P, Phillips, N, Abhishek, A, Roberts, T, Hodges, M, Talbot, G, Barber, V, Francis, A, Shields, AM, Duley, L, Hoogeboom, R, Willett, BJ, Scott, S, Parry-Jones, N, Eyre, TA, Plested, G, Vandici, G, Wandroo, FA, Hutchinson, C, Paneesha, S, Murray, DJ, Martinez-Calle, N, Jenkins, S, Heartin, E & Parry, HM 2025, 'A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial', The Lancet Haematology, vol. 12, no. 4, pp. e294-e303. https://doi.org/10.1016/S2352-3026(25)00008-0
BactiVac Network, MacLennan, CA, Cunningham, AF, Dean, JE, Pope, S, Balandyte-Shergill, E, Pillaye, J, Greenwood, BM & Adegbola, RA 2025, 'BactiVac, the Bacterial Vaccines Network', Vaccine, vol. 57, 127210. https://doi.org/10.1016/j.vaccine.2025.127210
Chin, AT, Ochs, HD, Kobayashi, R, Abolhassani, H, Alachkar, H, Barmettler, S, Baxendale, H, Boiling, K, Catanzaro, J, Chua, I, Coulter, T, Cunningham-Rundles, C, Elcombe, SE, Fischer, A, Grimbacher, B, Gupta, S, Herriot, R, Herwadkar, A, Imai, K, Inoue, S, Kirkpatrick, C, Knutsen, AP, Kumararatne, D, Lea, E, Lin, M-W, Litzman, J, Mahlaoui, N, Moriya, K, Nonoyama, S, Patel, S, Perez, E, Quinti, I, Hostoffer, RW, Rothenfusser, S, Sargur, R, Shields, A, Sogkas, G, Suan, D, Tan, T, Thomas, M, Warnatz, K, Younger, EM & Kuo, CY 2025, 'Clinical and Molecular Characteristics of X-Linked Agammaglobulinemia Patients 55 Years or Older', Journal of Allergy and Clinical Immunology: In Practice, vol. 13, no. 10, pp. 2806-2816.e6. https://doi.org/10.1016/j.jaip.2025.06.025
Dimbleby, B, Greenway, W, Burns, SO, Richter, AG & Shields, AM 2025, 'Health Care Utilisation in a Cohort of Patients with Primary and Secondary Antibody Deficiency in the United Kingdom', Journal of Clinical Immunology, vol. 45, no. 1, 18. https://doi.org/10.1007/s10875-024-01809-3
Peters, NE, Shields, AM, Hambleton, S & Richter, AG 2025, 'Learning from inborn errors of immunity and secondary immune deficiencies about vaccine immunogenicity, efficacy and safety', Clinical and Experimental Immunology. https://doi.org/10.1093/cei/uxaf059
Bagkou Dimakou, D, Peters, NE, Burns, SO, Richter, AG & Shields, AM 2025, 'Serum sBCMA in primary and secondary antibody deficiency', Clinical and Experimental Immunology. https://doi.org/10.1093/cei/uxaf065
Griffiths, K, Mellado, MR, Chung, R, Lally, J, McQueen, G, Sendt, K-V, Gillespie, A, Ibrahim, M, Richter, A, Shields, A, Ponsford, M, Jolles, S, Hodsoll, J, Pollak, TA, Upthegrove, R, Egerton, A & Maccabe, JH 2024, 'Changes in immunoglobulin levels during clozapine treatment in schizophrenia', Brain, Behavior, and Immunity, vol. 115, pp. 223-228. https://doi.org/10.1016/j.bbi.2023.10.001
Faustini, SE, Hodson, J, Birtwistle, J, Whitelegg, A, Masuka, S, Singo, M, Chigiga, J, Shields, A, Plant, T, Drayson, MT, Manavi, K, MacLennan, CA & Richter, AG 2024, 'Comparison of short- and long-term humoral immune responses to pneumococcal polysaccharide and glycoconjugate vaccines in an HIV-infected population', Journal of Infection, vol. 89, no. 5, 106282. https://doi.org/10.1016/j.jinf.2024.106282
Abstract
Dulobdas, V, Kirkwood, A, Gautama, B, Kasivisvanathan, S, Deshani, V, Mathew, A, Wilson, R, Malladi, R, Norman, J, George, L, Chavda, N, Besley, C, Uttenthal, B, Paneesha, S, Maybury, B, Shields, A & Chaganti, S 2025, 'Analysis of immune parameters and effect of immunoglobulin replacement therapy on infection, survival and non-relapse mortality following CD19 CAR T-cell therapy', Blood, vol. 146, no. Supplement 1, pp. 714-715. https://doi.org/10.1182/blood-2025-714
Comment/debate
Orf, K, Huissoon, A, Shields, A & Morris, EC 2026, 'Timing is everything: outcomes of allogeneic HSCT in adults with inborn errors of immunity', Bone Marrow Transplantation. https://doi.org/10.1038/s41409-026-02941-x
Review article
Kang, JT, Shields, AM, Mizuno, Y, De Biase, M, Ibrahim, MAA & MacCabe, JH 2026, 'A systematic review on the effects of clozapine on B-lymphocytes and immunoglobulins', Schizophrenia Research, vol. 294, pp. 198-214. https://doi.org/10.1016/j.schres.2026.05.005