Iremide Sanyaolu

Tell us a little bit about yourself and your background:
My research focuses on antimicrobial resistance, particularly exploring the link between bacterial energy states and efflux pumps, which are crucial for bacterial survival and resistance. Efflux pumps actively expel toxic compounds such as antibiotics and biocides from bacterial cells resulting in antibiotic resistance. Additionally, the energy level within bacterial cells not only drives these pumps but also potentially regulates key bacterial behaviours, such as biofilm formation, motility, and pathogenicity.

The primary aim of my research is to explore how the energy state of a bacterial cell influences efflux pump activity and how this interaction affects bacterial survival in diverse environments, such as during infections. By better understanding this relationship, my research aims to identify how the energy-efflux link allows bacteria to become resistant to antibiotics, how the energy state of the cell affects bacterial phenotypes, and how we can develop new strategies to improve antibiotic effectiveness.

Research Title:
Energy, Efflux and Resistance in Bacteria

Please provide a summary of your research project:
My research focuses on antimicrobial resistance, particularly exploring the link between bacterial energy states and efflux pumps, which are crucial for bacterial survival and resistance. Efflux pumps actively expel toxic compounds, such as antibiotics and biocides, from bacterial cells, contributing to antibiotic resistance. Additionally, the energy level within bacterial cells not only drives these pumps but also regulates key bacterial behaviours, such as biofilm formation, motility, and pathogenicity.

The primary aim of my research is to explore how the energy state of a bacterial cell influences efflux pump activity and how this interaction affects bacterial survival in diverse environments, such as during infections. By better understanding this relationship, my research aims to identify how the energy-efflux link allows bacteria to become resistant to antibiotics, how the energy state of the cell affects bacterial phenotypes, and how we can develop new strategies to improve antibiotic effectiveness. Hopefully my work will contribute to the broader scientific community and help tackle the growing issue of antimicrobial resistance!

What does being awarded the 125th Anniversary Scholarship for Black British Researchers mean to you? How has being awarded this scholarship inspired your academic journey?:
Being awarded the 125th Anniversary Scholarship for Black British Researchers is a significant milestone in my academic journey. It’s not only a recognition of my work so far but also a reminder of the importance of diversity in research. The scholarship has also inspired me to keep pushing forward, knowing that my contributions are part of a larger effort to increase representation in the sciences. It’s reinforced my commitment to advancing my research and encouraging others, especially from underrepresented groups, to consider careers in research and academia!

How have you found your experience at the University of Birmingham so far?:
My experience at the University of Birmingham has been incredibly rewarding. The University offers a wealth of academic resources and state-of-the-art facilities that have greatly supported my research and professional development as a PhD student. I have had the opportunity to attend various seminars, which have allowed me to connect with fellow researchers and stay updated on cutting-edge research both within the university and globally.

The University Graduate School organizes a wide range of events for postgraduate students, creating valuable opportunities to network, collaborate, and engage with peers from diverse disciplines. These events, from academic workshops to social gatherings, create a sense of community and provide platforms for building connections and support networks.

What advice would you give to someone considering applying for a Black British Researchers Scholarship or pursuing a PhD in your field?:
My advice for someone considering applying for a Black British Researchers Scholarship or pursuing a PhD in the field of Biology would be to just go for it! It can often feel intimidating at first, but you shouldn't allow that to stop you. Pursuing a PhD is a challenging and long journey but also incredibly rewarding. Embrace challenges as learning opportunities and stay focused on your passion for the field!

What impact do you hope your research will have on your field and the wider community, particularly underserved communities?:
I hope my research on AMR will have a lasting impact on both the field and the broader community. AMR is a growing global threat, and by understanding the mechanisms behind it, my work can help further our knowledge of AMR and lead to better strategies for combating resistant infections. In the future, my research could lead to novel therapeutic strategies, optimize the use of existing treatments, or help shape public health policies, ultimately reducing the global burden of infectious diseases. My goal is to make meaningful contributions to global health by addressing real-world challenges. As I continue my academic and professional journey, I am committed to using my research to create positive change and inspire others, particularly from underrepresented backgrounds, to pursue careers in science and research.