The institute is host to the largest group of microbiologists in Europe, with a focus on finding innovative ways to combat antimicrobial and antibiotic resistance, working across both bacterial and fungal pathogens. In order to do this, researchers have a number of different foci, including studies that involve the highly clinically relevant Gram negative bacteria Pseudomonas and how secreted proteins can cause antibody-dependant enhancement of infection. As well as this, researchers concentrate on bacterial efflux, the ability for bacteria to pump antibiotic out of the cell, causing diminished susceptibility to these drugs.