"The Vulgate revision of the Pauline Epistles was traditionally attributed to Saint Jerome although it is probably the work of an anonymous author that scholars identify with Rufinus the Syrian. To date the language and the style of these texts have not been thoroughly studied and many uncertainties regarding the authorship, the unity and the model of the Vulgate still remain. My paper aims to describe an innovative approach that can be highly effective in addressing these issues. This methodology is combined with the use of new digital tools which make possible to carry out a more extensive and accurate analysis than those previously undertaken. The method is meant to be internal as well as external and is based on a double approach combining quantitative analysis with qualitative examination of particularly interesting features. It consists of four stages: