Project aims to improve diagnosis and treatment for patients with anaemia

Ambulatory care specialists at the University of Birmingham, with support from Vifor Pharma UK Limited (VPUK), are working to develop and implement a population based anaemia diagnosis and treatment decision support service for routine healthcare delivery.

Anaemia is one of the most common laboratory abnormalities in both community and hospital settings. Anaemia is associated with a range of poorer health outcomes, including poorer quality of life, hospital admission, progression to institutional long term care and death yet there is evidence of inadequate use of tests to determine the cause of anaemia, leaving patients without a confirmed underlying diagnosis.

The new quality improvement project, led by Professor Dan Lasserson of the University of Birmingham and Sandwell and West Birmingham Hospitals NHS Trust, aims to construct a decision support algorithm to reduce the proportion of patients with inadequate investigation for anaemia. This will ensure the right combination of tests are performed for patients with anaemia detected for the first time, as well as reduce over-investigation where information is already contained within existing results in the laboratory database. The algorithm will, therefore, support rational diagnostic testing for anaemia, using existing resources tailored to the local population.

The algorithm guidance will be developed in conjunction with haematologists, acute physicians, gastroenterologists, and GPs, to ensure that the outputs are delivered in a usable and effective format, using electronic health records, enabling maximum generalisability across primary and secondary care.

Vifor Pharma, a leader in iron deficiency therapy, has provided financial support to this quality improvement programme.

Nick Ibrahim, VPUK General Manager, commented: “Irrespective of the effective treatments available, Vifor UK is proud to support a project that will allow better identification and management of people with iron deficiency and anaemia, with the potential to provide significant benefits to thousands of patients and the healthcare system in general.”

Dan Lasserson, Professor of Ambulatory Care at the University of Birmingham’s Institute of Applied Health Research, explained: “Anaemia is associated with a range of poorer health outcomes and seen commonly in community and hospital settings, but despite this, there is wide variation in approaches to diagnosis and management.

“Developing a population-based anaemia detection, diagnosis and management tool will standardise care to the large and diverse population in Birmingham, and ensure that at every healthcare contact, patients will have the right tests performed to find the underlying cause of anaemia.”

Notes for editors:

  • For more information please contact Beck Lockwood, Communications Manager (Science and Technology), University of Birmingham, tel: +44 0121 414 2772, or contact the press office on +44 (0) 7789 921 165.
  • The University of Birmingham is ranked amongst the world’s top 100 institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 6,500 international students from over 150 countries.
  • Vifor Pharma Group is a global pharmaceuticals company headquartered in Switzerland. It aims to become the global leader in iron deficiency, nephrology and cardio-renal therapies. The company is the partner of choice for pharmaceuticals and innovative patient-focused solutions. Vifor Pharma Group strives to help patients around the world with severe and chronic diseases lead better, healthier lives. The company develops, manufactures and markets pharmaceutical products for precision patient care. Vifor Pharma Group holds a leading position in all its core business activities and consists of the following companies: Vifor Pharma; Vifor Fresenius Medical Care Renal Pharma (a joint company with Fresenius Medical Care); Relypsa; and OM Pharma. Vifor Pharma Group is listed on the Swiss Stock Exchange (SIX Swiss Exchange, VIFN, ISIN: CH0364749348). 

References:

  1. Riva et al (2013). 'Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study'. Haematologica. DOI: 10.3324/haematol.13449.
  2. Lucca et al (2008). 'Association of Mild Anemia with Cognitive, Functional, Mood and Quality of Life Outcomes in the Elderly: The “Health and Anemia” Study.' PLOS ONE. DOI: 10.1371/journal.pone.0001920.
  3. McCartney et al (2018). 'The evaluation of anaemia in an older primary care population: retrospective population-based study.' BJGP Open. DOI: 10.3399/bjgpopen17X101157.