Recruitment and participating sites In 'SPHERE' SPHEREStudy documentationRecruitment and participating sitesPrivacyContact us SPHERE aims to recruit 966 patients (568 for the randomised controlled trial (RCT) and 398 for the observational cohort study) from seven NHS HIV out-patient clinics in England. Recruitment figures (as of 1 April 2025): RCT: 187 Observational cohort study: 272 NHS Trusts currently participating in SPHERE University Hospitals Sussex NHS Foundation Trust (contact uhsussex.ejcresearch@nhs.net) Barts Health NHS Trust (contact hafiza.rahman2@nhs.net or h.miras@nhs.net) Chelsea and Westminster Hospital NHS Foundation Trust (contact chelwest.crf1@nhs.net) King's College Hospital NHS Foundation Trust (contact kch-tr.caldecotresearch.nhs.net; 0207 848 5776) Manchester Univesity NHS Foundation Trust (contact mcsh.research@mft.nhs.uk) North Bristol NHS Trust Sheffield Teaching Hospitals NHS Foundation Trust (contact sth.specialistnursingteam@nhs.net) NHS Trusts currently in set-up None. All sites are now open to recruitment Associate PI Scheme SPHERE is participating in the Associate PI Scheme and applications to become an Associate PI trainee can be submitted from 15 August 2024. Information about the scheme, including how to apply, can be found on the NIHR Associate PI Scheme webpage.