CEDAM publications

Below is a list of the latest publications by CEDAM

Read, M., Brookes, K., Thornton, C., Fletcher, A., Nieto, H., Alshahrani, M., Khan, R., Borges de Souza, P., Zha, L., Webster, J., Alderwick, L., Campbell, M., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Cell Chemical Biology, 2021, 1-23. https://doi.org/10.1016/j.chembiol.2021.07.016
Grech, O., Clouter, A., Mitchell, J., Alimajstorovic, Z., Ottridge, R., Yiangou, A., Roque, M., Tahrani, A., Nicholls, M., Taylor, A., Shaheen, F., Arlt, W., Lavery, G., Shapiro, K., Mollan, S., & Sinclair, A. (2021). Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure. Brain Communications, 3(3), [fcab202]. https://doi.org/10.1093/braincomms/fcab202
Pickford, P., Lucey, M. A., Rujan, R-M., McGlone, E. R., Bitsi, S., Ashford, F., Corrêa, I. R., Hodson, D., Tomas, A., Deganutti, G., Reynolds, C. A., Owen, B., Tan, T. M., Minnion, J., Jones, B., & Bloom, S. R. (2021). Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist. Molecular metabolism, 51, [101242]. https://doi.org/10.1016/j.molmet.2021.101242
Nasteska, D., Cuozzo, F., Viloria, K., Johnson, E., Thakker, A., Bakar, R. B., Westbrook, R., Barlow, J., Hoang, M., Joseph, J., Lavery, G., Akerman, I., Cantley, J., Hodson, L., Tennant, D., & Hodson, D. (2021). Prolyl-4-hydroxylase 3 maintains β-cell glucose metabolism during fatty acid excess in mice. JCI Insight, 6(16), [e140288]. https://doi.org/10.1172/jci.insight.140288
Yiangou, A., Mitchell, J., Nicholls, M., Chong, Y. J., Vijay, V., Wakerley, B., Lavery, G., Tahrani, A., Mollan, S., & Sinclair, A. (2021). Obstructive sleep apnoea in women with idiopathic intracranial hypertension: a substudy of the Idiopathic Intracranial Hypertension Weight randomised controlled trial (IIH:WT). Journal of Neurology. https://doi.org/10.1007/s00415-021-10700-9
Bothou, C., Sharma, A., Oo, A., Kim, B., Perge, P., Igaz, P., Ronchi, C., Shapiro, I., & Hantel, C. (2021). Novel insights into the molecular regulation of ribonucleotide reductase in adrenocortical carcinoma treatment. Cancers, 13(16), [4200]. https://doi.org/10.3390/cancers13164200
Singh, P., Adderley, N., Hazlehurst, J., Price, M., Tahrani, A., Nirantharakumar, K., & Bellary, S. (Accepted/In press). Prognostic models for predicting remission of diabetes following bariatric surgery: a systematic review and meta-analysis. Diabetes Care.
Karavitaki, N. (Accepted/In press). Consensus on diagnosis and management of Cushing’s disease: a guideline update. The Lancet Diabetes and Endocrinology.
Marzook, A., Chen, S., Pickford, P., Lucey, M. A., Wang, Y., Corrêa, I. R., Broichhagen, J., Hodson, D., Salem, V., Rutter, G. A., Tan, T. M., Bloom, S. R., Tomas, A., & Jones, B. (2021). Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1. Biochemical Pharmacology, 190, [114656]. https://doi.org/10.1016/j.bcp.2021.114656
Abid, H. A., Inoue, A., & Gorvin, C. M. (2021). Heterogeneity of G-protein activation by the calcium-sensing receptor. Journal of Molecular Endocrinology, 67(2), 41-53. https://doi.org/10.1530/JME-21-0058
Lines, K. E., Gluck, A. K., Thongjuea, S., Bountra, C., Thakker, R. V., & Gorvin, C. M. (2021). The bromodomain inhibitor JQ1+ reduces calcium-sensing receptor activity in pituitary cell-lines. Journal of Molecular Endocrinology, 67(3), 83-94. https://doi.org/10.1530/JME-21-0030
Lucey, M., Ashik, T., Marzook, A., Wang, Y., Goulding, J., Oishi, A., Broichhagen, J., Hodson, D. J., Minnion, J., Elani, Y., Jockers, R., Briddon, S. J., Bloom, S. R., Tomas, A., & Jones, B. (Accepted/In press). Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking. Molecular Pharmacology. https://doi.org/10.1124/molpharm.121.000270
Singhal, R., Wiggins, T., Super, J., Alqahtani, A., Nadler, E. P., Ludwig, C., Tahrani, A., & Mahawar, K. (2021). 30-Day morbidity and mortality of bariatric metabolic surgery in adolescence during the COVID-19 pandemic - The GENEVA study. Pediatric Obesity, [e12832]. https://doi.org/10.1111/ijpo.12832
Olaniru, O., Cheng, J., Ast, J., Arvaniti, A., Atanes, P., Huang, GC., King, A., Jones, P., Broichhagen, J., Hodson, D., & Persaud, S. J. (2021). SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells. Molecular metabolism, 53, [101285]. https://doi.org/10.1016/j.molmet.2021.101285
Elliot, L., Frew, E., Mollan, S., Mitchell, J., Yiangou, A., Alimajstorovic, Z., Ottridge, R., Wakerley, B., Thaller, M., Grech, O., Singhal, R., Tahrani, A., Harrison, M., Sinclair, A., & Aguiar, M. (2021). Cost-effectiveness of bariatric surgery versus community weight management to treat obesity-related idiopathic intracranial hypertension: evidence from a single payer health care system. Surgery for Obesity and Related Diseases, 17(7), P1310-1316. https://doi.org/10.1016/j.soard.2021.03.020
Allen, S. L., Marshall, R. N., Edwards, S. J., Lord, J. M., Lavery, G. G., & Breen, L. (2021). The effect of young and old ex vivo human serum on cellular protein synthesis and growth in an in vitro model of aging. AJP: Cell Physiology, 321(1), C26-C37. https://doi.org/10.1152/ajpcell.00093.2021
Eigenbrodt, A., Ashina, H., Khan, S., Diener, H-C., Mitsikostas, D., Sinclair, A., Pozo-Rosich, P., Martelletti, P., Ducros, A., Lanteri-Minet, M., Braschinsky, M., Sanchez Del Rio, M., Daniel, O., Ozge, A., Mammadbayli, A., Arons, M., Skorobogatykh, K., Romanenko, V., Terwindt, G., ... Ashina, M. (2021). Diagnosis and management of migraine in ten steps: consensus statement. Nature Reviews Neurology. https://doi.org/10.1038/s41582-021-00509-5
Mollan, S., Grech, O., & Sinclair, A. (2021). Headache attributed to idiopathic intracranial hypertension (IIH) and persistent post-IIH headache: a narrative review. Headache. https://doi.org/10.1111/head.14125
Mollan, S., Mitchell, J., Ottridge, R., Aguiar, M., Alimajstorovic, Z., Cartwright, D., Grech, O., Lavery, G., Westgate, C., Vijay, V., Scotton, W., Wakerley, B., Matthews, T., Ansons, A., Hickman, S., Benzimra, J., Rick, C., Singhal, R., Tahrani, A., ... Sinclair, A. (2021). Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension: A Randomized Clinical Trial. JAMA Neurology, 78(6), 678-686. https://doi.org/10.1001/jamaneurol.2021.0659
Read, M., Brookes, K., Thornton, C., Nieto, H., Fletcher, A., Zha, L., Alderwick, L., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate radioiodide uptake in thyroid cancer. Abstract from 27TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH.
Mollan, S., & Sinclair, A. (2021). Outcomes measures in idiopathic intracranial hypertension. Expert Review of Neurotherapeutics. https://doi.org/10.1080/14737175.2021.1931127
Mollan, S., Chong, Y. J., Grech, O., Sinclair, A., & Wakerley, B. (2021). Current perspectives on idiopathic intracranial hypertension without papilloedema. Life, 11, [472]. https://doi.org/10.3390/life11060472
Westgate, C., Botfield, H., Alimajstorovic, Z., Yiangou, A., Walsh, M., Smith, G., Singhal, R., Mitchell, J., Grech, O., Markey, K., Hebenstreit, D., Tennant, D., Tomlinson, J., Mollan, S., Ludwig, C., Akerman, I., Lavery, G., & Sinclair, A. (2021). Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension. JCI Insight, 6(10), [e145346]. https://doi.org/10.1172/jci.insight.145346
Burden and Attitude to Resistant and Refractory (BARR) Study Group, Sacco, S., Lampl, C., Maassen Van Den Brink, A., Caponnetto, V., Braschinsky, M., Ducros, A., Little, P., Pozo-Rosich, P., Reuter, U., Ruiz De La Torre, E., Sanchez Del Rio, M., Sinclair, A., Martelletti, P., & Katsarava, Z. (2021). Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance. The Journal of Headache and Pain, 22, [39]. https://doi.org/10.1186/s10194-021-01252-4
Gorvin, C. M. (2021). Genetic causes of neonatal and infantile hypercalcaemia. Pediatric Nephrology. https://doi.org/10.1007/s00467-021-05082-z
Foster, P. (2021). Steroid sulphatase and its inhibitors: past, present and future. Molecules, 26(10), [2852]. https://doi.org/10.3390/molecules26102852
Mollan, S., Mytton, J., Tsermoulas, G., & Sinclair, A. (2021). Idiopathic intracranial hypertension: evaluation of admissions and emergency readmissions through the hospital episode statistic dataset between 2002–2020. Life, 11(5), [417]. https://doi.org/10.3390/life11050417
Shad, B. J., Thompson, J. L., Mckendry, J., Holwerda, A. M., Elhassan, Y. S., Breen, L., van Loon, L. J. C., & Wallis, G. A. (2021). Daily myofibrillar protein synthesis rates in response to low- and high-frequency resistance exercise training in healthy, young men. International journal of sport nutrition and exercise metabolism, 31(3), 209–216. https://doi.org/10.1123/ijsnem.2020-0274
Grech, O., Mollan, S., Wakerley, B., Fulton, D., Lavery, G., & Sinclair, A. (2021). The role of metabolism in migraine pathophysiology and susceptibility. Life: Physiology and Pathology, 11(5), [415]. https://doi.org/10.3390/life11050415
Aguiar, M., Frew, E., Mollan, S., Mitchell, J., Ottridge, R., Alimajstorovic, Z., Yiangou, A., Singhal, R., Tahrani, A., & Sinclair, A. (2021). The health economic evaluation of bariatric surgery versus a community weight management intervention analysis from the idiopathic intracranial hypertension weight trial (IIH:WT). Life, 11(5), [409]. https://doi.org/10.3390/life11050409
Akerman, I., Maestro, M. A., De Franco, E., Grau, V., Flanagan, S., Garcia-Hurtado, J., Mittler, G., Ravassard, P., Piemonti, L., Ellard, S., Hattersley, A. T., & Ferrer, J. (2021). Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports, 35(2), [108981]. https://doi.org/10.1016/j.celrep.2021.108981
Powell, L., & Foster, P. (2021). Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy. Cancer Medicine, 10(8), 2812-2825. https://doi.org/10.1002/cam4.3836
Antza, C., Ottridge, R., Patel, S., Slinn, G., Tearne, S., Nicholls, M., Cooper, B., Ali, A., & Tahrani, A. (2021). The impact of sleep disorders on microvascular complications in patients with type 2 diabetes (SLEEP T2D): the protocol of a cohort study and feasibility randomised control trial. Pilot and Feasibility Studies, 7(1), [80]. https://doi.org/10.1186/s40814-021-00817-z
Mueller, J. W., Vogg, N., Lightning, T. A., Weigand, I., Ronchi, C., Foster, P., & Kroiss, M. (2021). Steroid sulfation in adrenal tumors. Journal of Clinical Endocrinology and Metabolism, 2021(00), [dgab182]. https://doi.org/10.1210/clinem/dgab182
Hakami, O., Ahmed, S. K., & Karavitaki, N. (2021). Epidemiology and mortality of Cushing’s syndrome. Best practice & research. Clinical endocrinology & metabolism, [101521]. https://doi.org/10.1016/j.beem.2021.101521
Lightning, T. A., Gesteira, T. F., & Mueller, J. W. (2021). Steroid disulfates - Sulfation double trouble Molecular and Cellular Endocrinology. Molecular and Cellular Endocrinology, 524, [111161]. https://doi.org/10.1016/j.mce.2021.111161
Viloria, K., Hewison, M., & Hodson, D. (2021). Vitamin D-binding protein/GC-globulin: a novel regulator of alpha cell function and glucagon secretion. Journal of Physiology. https://doi.org/10.1113/JP280890
Read, M., Brookes, K., Thornton, C., Fletcher, A., Nieto, H., Alshahrani, M., Khan, R., Borges de Souza, P., Zha, L., Webster, J., Alderwick, L., Campbell, M., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate the NIS symporter. SSRN. https://doi.org/10.2139/ssrn.3797274
Barnard, L., Schiffer, L., Du-Toit, R. L., Tamblyn, J., Chen, S., Africander, D., Arlt, W., Foster, P., & Storbeck, K-H. (2021). 11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool. Endocrinology, 162(3), [bqaa231]. https://doi.org/10.1210/endocr/bqaa231
Reincke, M., Albani, A., Assie, G., Bancos, I., Brue, T., Buchfelder, M., Chabre, O., Ceccato, F., Daniele, A., Detomas, M., Di Dalmazi, G., Elenkova, A., Findling, J., Grossman, A., Gomez-Sanchez, C., Heaney, A., Honegger, J., Karavitaki, N., Lacroix, A., ... Ritzel, K. (2021). Corticotroph tumor progression after bilateral adrenalectomy (Nelson’s syndrome): systematic review and expert consensus recommendations. European Journal of Endocrinology, 184(3), P1–P16. https://doi.org/10.1530/EJE-20-1088
Riley, J., Antza, C., Kempegowda, P., Subramanian, A., Chandan, J. S., Gokhale, K., Thomas, N., Sainsbury, C., Tahrani, A. A., & Nirantharakumar, K. (2021). Social deprivation and incident diabetes-related foot disease in patients with type 2 diabetes: a population-based cohort study. Diabetes Care, 44(3), 731-739. https://doi.org/10.2337/dc20-1027
Aojula, N., Ready, A., Gittoes, N., & Hassan-Smith, Z. (2021). Management of Parathyroid Disease during the COVID-19 Pandemic. Journal of Clinical Medicine, 10(5), [920]. https://doi.org/10.3390/jcm10050920
Pezhman, L., Tahrani, A., & Chimen, M. (2021). Dysregulation of Leukocyte Trafficking in Type 2 Diabetes: Mechanisms and Potential Therapeutic Avenues. Frontiers in cell and developmental biology, 9, [624184]. https://doi.org/10.3389/fcell.2021.624184
Weigand, I., Ronchi, C., Vanselow, J. T., Bathon, K., Lenz, K., Herterich, S., Schlosser, A., Kroiss, M., Fassnacht, M., Calebiro, D., & Sbiera, S. (2021). PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser¹¹⁴phosphorylation. Science Advances, 7(8), [eabd4176]. https://doi.org/10.1126/sciadv.abd4176
Smeuninx, B., Elhassan, Y. S., Manolopoulos, K. N., Sapey, E., Rushton, A. B., Edwards, S. J., Morgan, P. T., Philp, A., Brook, M. S., Gharahdaghi, N., Smith, K., Atherton, P. J., & Breen, L. (2021). The effect of short-term exercise prehabilitation on skeletal muscle protein synthesis and atrophy during bed rest in older men. Journal of cachexia, sarcopenia and muscle, 12(1), 52-69. https://doi.org/10.1002/jcsm.12661
Wang, J., Cooper, J., Gokhale, K., Acosta-Mena , D., Dhalla , S., Byne , N., Chandan, J. S., Anand, A., Okoth, K., Subramanian, A., Bangash, M., Jackson, T., Zemedikun, D., Taverner, T., Hanif, W., Ghosh, S., Narendran, P., Toulis, K., Tahrani, A., ... Nirantharakumar, K. (2021). Association of metformin with susceptibility to COVID-19 in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, [dgab067]. https://doi.org/10.1210/clinem/dgab067
Gorvin, C. M. (2021). Calcium-sensing receptor signaling - how human disease informs biology. Current Opinion in Endocrine and Metabolic Research, 16, 10-18. https://doi.org/10.1016/j.coemr.2020.06.007
Fenton, C., Martin, C., Jones, R., Croft, A., Campos, J., Naylor, A., Taylor, A., Chimen, M., Cooper, M., Lavery, G., Raza, K., & Hardy, R. (2021). Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids. Annals of the Rheumatic Diseases, 80(2), 250-260. https://doi.org/10.1136/annrheumdis-2020-218493
Subramanian, A., Idkowiak, J., Toulis, K., Thangaratinam, S., Arlt, W., & Nirantharakumar, K. (2021). Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review. European Journal of Endocrinology, 184(1), 51–64. https://doi.org/10.1530/EJE-20-0296
Gorvin, C. M. (2021). GPCRs and Endocrinology. In Reference Module in Biomedical Sciences Elsevier. https://doi.org/10.1016/B978-0-12-820472-6.00020-7
Nasteska, D., Fine, N., Ashford, F., Cuozzo, F., Viloria, K., Smith, G., Dahir, A., Dawson, P. W. J., Lai, Y-C., Bastidas-Ponce, A., Bakhti, M., Rutter, G., Fiancette, R., Nano, R., Piemonti, L., Lickert, H., Zhou, Q., Akerman, I., & Hodson, D. (2021). PDX1^LOW MAFA^LOW β-cells contribute to islet function and insulin release. Nature Communications, 12(1), [674]. https://doi.org/10.1038/s41467-020-20632-z
Yiangou, A., Mitchell, J., Fisher, C., Edwards, J., Vijay, V., Alimajstorovic, Z., Grech, O., Lavery, G., Mollan, S., & Sinclair, A. (2021). Erenumab for headaches in idiopathic intracranial hypertension: a prospective open-label evaluation. Headache, 61(1), 157-169. https://doi.org/0.1111/head.14026
Shahzad, A. (2021). Dielectric characterization of ex vivo ovine and human adrenal glands for microwave thermal ablation applications. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 2021(00), 1-9. https://doi.org/10.1109/JERM.2021.3052108
Hardy, R., Botfield, H., Markey, K., Mitchell, J., Alimajstorovic, Z., Westgate, C., Sagmeister, M., Fairclough, R., Ottridge, R., Yiangou, A., Storbeck, K-H., Taylor, A., Gilligan, L., Arlt, W., Stewart, P., Tomlinson, J., Mollan, S., Lavery, G., & Sinclair, A. (2021). 11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension. Journal of Clinical Endocrinology and Metabolism, 106(1), 174-187. https://doi.org/10.1210/clinem/dgaa766
Singhal, R., Tahrani, A., Ludwig, C., Mahawar, K., & GENEVA collaborators (2021). Global 30-day outcomes after bariatric surgery during the COVID-19 pandemic (GENEVA): an international cohort study. The Lancet Diabetes and Endocrinology, 9(1), [7-9]. https://doi.org/10.1016/S2213-8587(20)30375-2
Singh, P., Adderley, N., Subramanian, A., Gokhale, K., Singhal, R., Toulis, K., Bellary, S., Nirantharakumar, K., & Tahrani, A. (2021). The impact of bariatric surgery on incident microvascular complications in patients with type 2 diabetes: a matched controlled population-based retrospective cohort study. Diabetes Care, 44(1), 116-124. https://doi.org/10.2337/dc20-0571
Lempesis, I. G., Goossens, G. H., & Manolopoulos, K. N. (2021). Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound. Adipocyte, 10(1), 119-123. https://doi.org/10.1080/21623945.2021.1888471
Abbott, S., Parretti, H., Hazlehurst, J., & Tahrani, A. (2020). Socio-demographic predictors of uptake of a virtual group weight management program during the COVID-19 pandemic. Journal of Human Nutrition and Dietetics. https://doi.org/10.1111/jhn.12850
McLean, B., Wong, C. K., Campbell, J., Hodson, D., Trapp, S., & Drucker, D. (2020). Revisiting the complexity of GLP-1 action-from sites of synthesis to receptor activation. Endocrine Reviews. https://doi.org/10.1210/endrev/bnaa032
Parretti, H., Subramanian, A., Adderley, N., Abbott, S., Tahrani, A., & Nirantharakumar, K. (2020). Post-bariatric surgery nutritional follow-up in primary care: a population-based cohort study. British Journal of General Practice , 2020(00), 1-23. https://doi.org/10.3399/bjgp20X714161
Hazlehurst, J., Logue, J., Parretti, H., Abbott, S., Brown, A., Pournaras, D., & Tahrani, A. (2020). Developing integrated clinical pathways for the management of clinically severe adult obesity: A critique of NHS England policy. Current Obesity Reports, 9, 530–543. https://doi.org/10.1007/s13679-020-00416-8
Vusirikala, A., Thomas, T., Bhala, N., Tahrani, A. A., Thomas, G. N., & Nirantharakumar, K. (2020). Impact of obesity and metabolic health status in the development of non-alcoholic fatty liver disease (NAFLD): a United Kingdom population-based cohort study using the health improvement network (THIN). BMC Endocrine Disorders, 20(1), [96]. https://doi.org/10.1186/s12902-020-00582-9
Ast, J., Arvaniti, A., Fine, N. H. F., Nasteska, D., Ashford, F. B., Stamataki, Z., Koszegi, Z., Bacon, A., Jones, B. J., Lucey, M. A., Sasaki, S., Brierley, D. I., Hastoy, B., Tomas, A., D’agostino, G., Reimann, F., Lynn, F. C., Reissaus, C. A., Linnemann, A. K., ... Hodson, D. J. (2020). Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 11(1), [467 ]. https://doi.org/10.1038/s41467-020-14309-w
Webster, J., Kempen, L., Hardy, R., & Langen, R. (2020). Inflammation and skeletal muscle wasting during cachexia. Frontiers in Physiology, 2020, [597675]. https://doi.org/10.3389/fphys.2020.597675
Mollan, S., Grech, O., Alimajstorovic, Z., Wakerley, B., & Sinclair, A. (2020). New horizons for Idiopathic intracranial hypertension. British Medical Bulletin, [ldaa034]. https://doi.org/10.1093/bmb/ldaa034
Fang, Z., Chen, S., Manchanda, Y., Bitsi, S., Pickford, P., David, A., Shchepinova, M., Corrêa, I. R., Hodson, D., Broichhagen, J., Tate, E., Reimann, F., Salem, V., Rutter, G., Tan, T. M., Bloom, S. R., Tomas, A., & Jones, B. (2020). Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells. International Journal of Molecular Sciences, 21(21), [8404]. https://doi.org/10.3390/ijms21218404
Graham, Y., Mahawar, K., Riera, M., Islam, O., Bhasker, A., Wilson, M., Tahrani, A., Moize, V., Leal, A., & Ha, C. (2020). Emotional resilience and bariatric surgical teams: a priority in the pandemic. Obesity surgery. https://doi.org/10.1007/s11695-020-05083-1, https://doi.org/10.1007/s11695-020-05083-1
Vijay, V., Mollan, S., Mitchell, J., Bilton, E., Alimajstorovic, Z., Markey, K., Fong, A., Walker, J., Lyons, H., Yiangou, A., Tsermoulas, G., Brock, K., & Sinclair, A. (2020). Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension. JAMA Ophthalmology. https://doi.org/10.1001/jamaophthalmol.2020.4242
Chifu, I., Heinze, B., Fuss, C., Lang, K., Kroiss, M., Kircher, S., Ronchi, C., Altieri, B., Schirbel, A., Fassnacht, M., & Hahner, S. (Accepted/In press). Impact of the Chemokine Receptors CXCR4 and CXCR7 on Clinical Outcome in Adrenocortical Carcinoma. Frontiers in Endocrinology.
Okoth, K., Chandan, J., Marshall, T., Thangaratinam, S., Thomas, G. N., Nirantharakumar, K., & Adderley, N. (2020). The association between the reproductive health of young women and cardiovascular disease in later life: An umbrella review. BMJ, 371, 1-21. [m3502]. https://doi.org/10.1136/bmj.m3502
Majidi, F., Martino, S., Kondakci, M., Antke, C., Haase, M., Chortis, V., Arlt, W., Ronchi, C., Fassnacht, M., Laurent, C., Petit, J-M., Casasnovas, O., Habra, M., Kanji, A., Salvatori, R., Ho, A. T. N., Spyroglou, A., Beuschlein, F., Villa, D., ... Gattermann, N. (2020). Clinical spectrum of primary adrenal lymphoma: results of a multicenter cohort study. European Journal of Endocrinology, 183(4), 453–462. https://doi.org/10.1530/EJE-19-0506
Carrat, G. R., Haythorne, E., Tomas, A., Haataja, L., Müller, A., Arvan, P., Piunti, A., Cheng, K., Huang, M., Pullen, T. J., Georgiadou, E., Stylianides, T., Amirruddin, N. S., Salem, V., Distaso, W., Cakebread, A., Heesom, K. J., Lewis, P. A., Hodson, D. J., ... Rutter, G. A. (2020). The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis. Molecular metabolism, 40, [101015]. https://doi.org/10.1016/j.molmet.2020.101015
Yiangou, A., Mitchell, J., Vijay, V., Grech, O., Bilton, E., Lavery, G., Fisher, C., Edwards, J., Mollan, S., & Sinclair, A. (2020). Calcitonin gene related peptide monoclonal antibody treats headache in patients with active idiopathic intracranial hypertension. The Journal of Headache and Pain, 21(1), [116 ]. https://doi.org/10.1186/s10194-020-01182-7
Bellary, S., Tahrani, A., & Barnett, A. H. (2020). Improving management of diabetic kidney disease: will GLP-1 receptor agonists have a role? The Lancet Diabetes and Endocrinology. https://doi.org/10.1016/S2213-8587(20)30301-6
Virdee, J., Larcombe, S., Vijay, V., Sinclair, A., Dayan, M., & Mollan, S. (2020). Reviewing the recent developments in idiopathic intracranial hypertension. Ophthalmology and Therapy. https://doi.org/10.1007/s40123-020-00296-0
Fountas, A., & Karavitaki, N. (2020). Nelson’s syndrome: an update. Endocrinology and Metabolism Clinics of North America, 49(3), 413-432. https://doi.org/10.1016/j.ecl.2020.05.004
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Gittoes, N., Criseno, S., Appelman-Dijkstra, N., Bollerslev, J., Canalis, E., Rejnmark, L., & Hassan-Smith, Z. (2020). Endocrinology in the time of COVID-19: Management of calcium metabolic disorders and osteoporosis. European Journal of Endocrinology, 183(2), G57-G65. https://doi.org/10.1530/EJE-20-0385
Adderley, N., Subramanian, A., Toulis, K., Gokhale, K., Taverner, T., Hanif, W., Haroon, S., Thomas, G. N., Sainsbury, C., Tahrani, A., & Nirantharakumar, K. (2020). Obstructive sleep apnea, a risk factor for cardiovascular and microvascular disease in patients with type 2 diabetes: findings from a population-based cohort study. Diabetes Care, 43(8), 1868-1877. https://doi.org/10.2337/dc19-2116
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Grech, O., Mollan, S., Wakerley, B., Alimajstorovic, Z., Lavery, G., & Sinclair, A. (2020). Emerging themes in Idiopathic Intracranial Hypertension. Journal of Neurology. https://doi.org/10.1007/s00415-020-10090-4
Read, M. L., Brookes, K., Thornton, C. E. M., Fletcher, A., Alshahrani, M., Khan, R., Nieto, H. R., Souza, P. B. D., Webster, J. R. M., Alderwick, L. J., Boelaert, K., Smith, V. E., & McCabe, C. J. (2020, Jul 22). New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer. https://doi.org/10.1101/2020.07.21.213967
Ntali, G., Hakami, O., Wattegama, M., Ahmed, S., & Karavitaki, N. (2020). Mortality of patients with Cushing’s disease. Experimental and Clinical Endocrinology and Diabetes. https://doi.org/10.1055/a-1197-6380
Poc, P., Gutzeit, V., Ast, J., Lee, J., Jones, B. J., D’este, E., Mathes, B., Lehmann, M., Hodson, D., Levitz, J., & Broichhagen, J. (2020). Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates. Chemical Science, 1-13. https://doi.org/10.1039/d0sc02794d
Abbott, S., Lawson, J., Singhal, R., Parretti, H., & Tahrani, A. (2020). Weight loss during medical weight management does not predict weight loss after bariatric surgery: a retrospective cohort study. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.
Jouinot, A., Lippert, J., Fassnacht, M., De La Villeon, B., Septier, A., Neou, M., Perlemoine, K., Appenzeller, S., Sibony, M., Gaujoux, S., Dousset, B., Libe, R., Groussin, L., Ronchi, C., Assie', G., & Bertherat, J. (Accepted/In press). Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma. Endocrine Connections. https://doi.org/10.1530/EC-20-0228
Prete, A., Taylor, A., Bancos, I., Smith, D., Foster, M., Kohler, S., Fazal-Sanderson, V., Komninos, J., O'Neil, D., Vas, D., Mowatt, C., Mihai, R., Fallowfield, J., Annane, D., Lord, J., Keevil, B., Wass, J., Karavitaki, N., & Arlt, W. (2020). Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery. Journal of Clinical Endocrinology and Metabolism, 105(7), 2262–2274. https://doi.org/10.1210/clinem/dgaa133
Flint, S. W., & Tahrani, A. (2020). COVID-19 and obesity-lack of clarity, guidance, and implications for care. The Lancet Diabetes and Endocrinology, 8(6), 474-475. https://doi.org/10.1016/S2213-8587(20)30156-X
Sacco, S., Braschinsky, M., Ducros, A., Lampl, C., Little, P., Maassen Van Den Brink, A., Pozo-Rosich, P., Reuter, U., Ruiz De La Torre, E., Sanchez Del Rio, M., Sinclair, A., Katsarava, Z., & Martelletti, P. (2020). European headache federation consensus on the definition of resistant and refractory migraine : developed with the endorsement of the European Migraine & Headache Alliance (EMHA). The Journal of Headache and Pain, 21, [76]. https://doi.org/10.1186/s10194-020-01130-5
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Kemkem, Y., Nasteska, D., De Bray, A., Bargi-Souza, P., Peliciari-Garcia, R., Guillou, A., Mollard, P., Hodson, D., & Schaeffer, M. (2020). Maternal hypothyroidism in mice influences glucose metabolism in adult offspring. Diabetologia. https://doi.org/10.1007/s00125-020-05172-x
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Fleseriu, M., Karavitaki, N., & Dekkers, O. (2020). Endocrinology in the time of COVID-19: management of pituitary tumours. European Journal of Endocrinology. https://doi.org/10.1530/EJE-20-0473
Hodson, D., & Rorsman, P. (2020). A variation on the theme: SGLT2 inhibition and glucagon secretion in human islets. Diabetes, 69(5), 864-866. https://doi.org/10.2337/dbi19-0035
Dharmaraj, P., Gorvin, C. M., Soni, A., Nelhans, N., Olesen, M., Boon, H., Cranston, T., Thakker, R., & Hannan, F. (2020). Neonatal hypocalcemic seizures in offspring of a mother with familial hypocalciuric hypercalcemia type 1 (FHH1). Journal of Clinical Endocrinology and Metabolism, 105(5), 1393–1400. https://doi.org/10.1210/clinem/dgaa111
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El-gamal, M. I., Zaraei, S., Foster, P. A., Anbar, H. S., El-gamal, R., El-awady, R., & Potter, B. V. L. (2020). A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry, 28(8), [115406]. https://doi.org/10.1016/j.bmc.2020.115406
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Gittoes, N., Lord, J., Doyle, A., Robinson, J., Nightingale, P., Greig, C., Welford, A., & Lanham-New, S. (Accepted/In press). The influence of combined vitamin D3 supplementation and resistance exercise training on musculoskeletal health in older men and women (EXVITD): protocol for a randomized controlled trial. BMJ open.
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Tresoldi, A., Sumilo, D., Perrins, M., Toulis, K., Prete, A., Reddy, N., Wass, J., Arlt, W., & Nirantharakumar, K. (2020). Increased infection risk in Addison's disease and congenital adrenal hyperplasia: a primary care database cohort study. Journal of Clinical Endocrinology and Metabolism, 105(2), 1-2. [dgz006]. https://doi.org/10.1210/clinem/dgz006
Singh, P., Subramanian, A., Adderley, N., Gokhale, K., Shinghal, R., Bellary, S., Nirantharakumar, K., & Tahrani, A. (2020). Impact of bariatric surgery on cardiovascular outcomes and mortality: a population‐based cohort study. British Journal of Surgery. https://doi.org/10.1002/bjs.11433
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Kahal, H., Tahrani, A. A., Kyrou, I., Dimitriadis, G. K., Kimani, P. K., Barber, T. M., Nicholls, M., Ali, A., Weickert, M. O., & Randeva, H. S. (2020). The relationship between obstructive sleep apnoea and quality of life in women with polycystic ovary syndrome: a cross-sectional study. Therapeutic Advances in Endocrinology and Metabolism, 11, 2042018820906689. https://doi.org/10.1177/2042018820906689
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Storbeck, K-H., Schiffer, L., Baranowski, E., Chortis, V., Prete, A., Barnard, L., Gilligan, L., Taylor, A., Idkowiak, J., Arlt, W., & Shackleton, C. (2019). Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism. Endocrine Reviews, 40(6), 1605-1625. https://doi.org/10.1210/er.2018-00262
Alexandraki, K. I., Kaltsas, G. A., Karavitaki, N., & Grossman, A. (2019). The medical therapy of craniopharyngiomas: the way ahead. Journal of Clinical Endocrinology and Metabolism, 104(12), 5751–5764. https://doi.org/10.1210/jc.2019-01299
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Schiffer, L., Barnard, L., Baranowski, E., Gilligan, L., Taylor, A., Arlt, W., Shackleton, C., & Storbeck, K-H. (2019). Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review. The Journal of Steroid Biochemistry and Molecular Biology, 194, [105439]. https://doi.org/10.1016/j.jsbmb.2019.105439
Lithgow, K., Batra, R., Matthews, T., & Karavitaki, N. (2019). Management of endocrine disease: visual morbidity in patients with pituitary adenoma. European Journal of Endocrinology, 181(5), R185-R197. https://doi.org/10.1530/EJE-19-0349
Torlinska, B., Nichols, L., Mohammed, M. A., McCabe, C., & Boelaert, K. (2019). Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort. Thyroid, 29(10), 1380-1389. https://doi.org/10.1089/thy.2018.0731
Lippincott, M. F., León, S., Chan, Y., Fergani, C., Talbi, R., Farooqi, I. S., Jones, C. M., Arlt, W., Stewart, S. E., Cole, T. R., Terasawa, E., Hall, J. E., Shaw, N. D., Navarro, V. M., & Seminara, S. B. (2019). Hypothalamic reproductive endocrine pulse generator activity independent of neurokinin B and dynorphin signaling. Journal of Clinical Endocrinology and Metabolism, 104(10), 4304-4318. https://doi.org/10.1210/jc.2019-00146
Shad, B., Thompson, J., Holwerda, A., Stocks, B., Elhassan, Y., Philp, A., van Loon, L., & Wallis, G. (2019). One week of step reduction lowers myofibrillar protein synthesis rates in young men. Medicine and Science in Sports and Exercise, 51(10), 2125-2134. https://doi.org/10.1249/MSS.0000000000002034
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Lavrentaki, A., Thomas, T., Subramanian, A., Valsamakis, G., Thomas, N., Toulis, K. A., Wang, J., Daly, B., Saravanan, P., Sumilo, D., Mastorakos, G., Tahrani, A. A., & Nirantharakumar, K. (2019). Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis. Journal of Diabetes and its Complications, 33(10), 107401. https://doi.org/10.1016/j.jdiacomp.2019.06.006
Karavitaki, N., & Souteiro, P. (2019). Dopamine agonist resistant prolactinomas - any alternative medical treatment? Pituitary. https://doi.org/10.1007/s11102-019-00987-3
de Vries, F., Bruin, M., Lobatto, D. J., Dekkers, O., Schoones, J. W., van Furth, W. R., Pereira, A., Karavitaki, N., Biermasz, N. R., & Zamanipoor Najafabadi, A. H. (2019). Opioids and their endocrine effects: a systematic review and meta-analysis. The Journal of clinical endocrinology and metabolism, [dgz022]. https://doi.org/10.1210/clinem/dgz022
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Thayakaran, T., Adderley, N., Sainsbury, C., Torlinska, B., Boelaert, K., Sumilo, D., Price, M., Thomas, G. N., Toulis, K., & Nirantharakumar, K. (2019). Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. BMJ, 366, [l4892]. https://doi.org/10.1136/bmj.l4892
Schiffer, L., Adaway, J. E., Arlt, W., & Keevil, B. G. (2019). A liquid chromatography-tandem mass spectrometry assay for the profiling of classical and 11-oxygenated androgens in saliva. Annals of Clinical Biochemistry, 56(5), 564-573. https://doi.org/0.1177/0004563219847498
Adderley, N., Subramanian, A., Nirantharakumar, K., Yiangou, A., Gokhale, K., Mollan, S., & Sinclair, A. (2019). Association between idiopathic intracranial hypertension and risk of cardiovascular diseases in women in the United Kingdom. JAMA Neurology, 76(9), 1088-1098. https://doi.org/10.1001/jamaneurol.2019.1812
Elhassan, Y. S., Kluckova, K., Fletcher, R. S., Schmidt, M. S., Garten, A., Doig, C. L., Cartwright, D. M., Oakey, L., Burley, C. V., Jenkinson, N., Wilson, M., Lucas, S. J. E., Akerman, I., Seabright, A., Lai, Y., Tennant, D. A., Nightingale, P., Wallis, G. A., Manolopoulos, K. N., ... Lavery, G. G. (2019). Nicotinamide riboside augments the aged human skeletal muscle NAD⁺ metabolome and induces transcriptomic and anti-inflammatory signatures. Cell Reports, 28(7), 1717-1728.e6. https://doi.org/10.1016/j.celrep.2019.07.043
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Tampourlou, M., Arlt, W., Gittoes, N., O'reilly, M., & Karavitaki, N. (2017). Outcome of non-functioning pituitary adenomas that regrow after primary treatment: a study from two large specialist UK centers. Abstract from 19th European Congress of Endocrinology, Lisbon, Portugal. https://doi.org/10.1530/endoabs.49.GP180
Santharam, S., Tampourlou, M., Arlt, W., Ayuk, J., Gittoes, N., Toogood, A., Webster, R., & Karavitaki, N. (2017). Prolactinomas diagnosed after menopause: presentation and outcomes from a large specialist centre. Abstract from 19th European Congress of Endocrinology, Lisbon, Portugal. https://doi.org/10.1530/endoabs.49.EP1051
Lebbe, M., Taylor, A., Visser, J. A., Kirkman-Brown, J., Woodruff, T. K., & Arlt, W. (2017). The steroid metabolome in the isolated ovarian follicle and its response to androgen exposure and antagonism. Endocrinology, 158(5), 1474-1485. https://doi.org/10.1210/en.2016-1851
Arlt, W., Lang, K., Sitch, A., Dietz, A. S., Rhayem, Y., Bancos, I., Feuchtinger, A., Chortis, V., Gilligan, L., Ludwig, P., Riester, A., Asbach, E., Hughes, B., O'Neil, D., Bidlingmaier, M., Tomlinson, J. W., Hassan-Smith, Z., Rees, D. A., Adolf, C., ... Reincke, M. (2017). Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism. JCI Insight, 2(8), [e93136]. https://doi.org/10.1172/jci.insight.93136
Tahrani, A. A. (2017). Ethnic Differences In The Pathogenesis of Obstructive Sleep Apnoea: Exploring Non-Anatomical Factors. Respirology. https://doi.org/10.1111/resp.13057
Mitchell, R. K., Nguyen-Tu, M-S., Chabosseau, P., Callingham, R. M., Pullen, T. J., Cheung, R., Leclerc, I., Hodson, D. J., & Rutter, G. A. (2017). The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis and Ca2+ dynamics in adult mice. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M117.784629
Manolopoulos, K. N., O'Reilly, M. W., Bujalska, I. J., Tomlinson, J. W., & Arlt, W. (2017). Acute hypercortisolemia exerts depot-specific effects on abdominal and femoral adipose tissue function. Journal of Clinical Endocrinology and Metabolism, 102(4), 1091-1101. https://doi.org/10.1210/jc.2016-3600
Bancos, I., Hazeldine, J., Chortis, V., Hampson, P., Taylor, A. E., Lord, J., & Arlt, W. (2017). Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality. European Journal of Endocrinology, 176(4), 471-480. https://doi.org/10.1530/EJE-16-0969
Welch, C., Hassan-Smith, Z., Greig, C., Lord, J., & Jackson, T. (2017). Acute Sarcopenia Secondary to Hospitalisation – An Emerging Condition Affecting Older Adults. Aging and Disease, 8(6). https://doi.org/10.14336/AD.2017.0315
Mehta, Z., Johnston, N., Nguyen-Tu, M-S., Broichhagen, J., Schultz, P. G., Larner, D., Leclerc, I., Trauner, D., Rutter, G., & Hodson, D. J. (2017). Remote control of glucose homeostasis in vivo using photopharmacology. Scientific Reports, 7, [291]. https://doi.org/10.1038/s41598-017-00397-0
Tahrani, A. (2017). Peripheral and Autonomic Neuropathy in South Asians and White Caucasians with Type 2 Diabetes Mellitus: Possible Explanations for Epidemiological Differences. Journal of Diabetes Research, [1273789]. https://doi.org/10.1155/2017/1273789
Weigel, M., Hahner, S., Sherlock, M., Agha, A., Behan, L. A., Stewart, P., Arlt, W., Beier, D., Frey, K., Zopf, K., & Quinkler, M. (2017). Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer. Clinical Endocrinology, 86(4), 499-505. https://doi.org/10.1111/cen.13302
Gilligan, L., Gondal, A., Tang, V., Hussain, M. T., Arvaniti, A., Hewitt, A-M., & Foster, P. A. (2017). Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for Hormone Replacement Therapy. Frontiers in Pharmacology, 8, [103]. https://doi.org/10.3389/fphar.2017.00103
O'reilly, M., Kempegowda, P., Jenkinson, C., Taylor, A., Quanson, J. L., Storbeck, K-H., & Arlt, W. (2017). 11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 102(3), 840-848. https://doi.org/10.1210/jc.2016-3285
May, C. J. H., Asis, M., Arlt, W., Guest, P., O'reilly, M., & Karavitaki, N. (2017). Bilateral adrenal haemorrhage. QJM: An International Journal of Medicine, 110(3), 169-171. https://doi.org/10.1093/qjmed/hcw212
Romanò, N., Guillou, A., Hodson, D. J., Martin, A. O., & Mollard, P. (2017). Multiple-scale neuroendocrine signals connect brain and pituitary hormone rhythms. National Academy of Sciences. Proceedings, 114(9), 2379–2382. https://doi.org/10.1073/pnas.1616864114
Hassan-Smith, Z. K., Jenkinson, C., Smith, D., Hernandez, I., Morgan, S., Crabtree, N. J., Gittoes, N., Keevil, B. G., Stewart, P. M., & Hewison, M. (2017). 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression. PLoS ONE, 12(2), [e0170665]. https://doi.org/10.1371/journal.pone.0170665
Poole, V., Fletcher, A., Modasia, B., Sharma, N., Thompson, R., Imruetaicharoenchoke, W., Read, M., Boelaert, K., McCabe, C., & Smith, V. (2017). Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors. Thyroid Research, 10(Suppl 1)(2), 2. [O2]. https://doi.org/10.1186/s13044-016-0036-8
Gittoes, O., & Gittoes, N. (2017). Breathlessness and neck swelling after a rugby game. BMJ, 356, [j311]. https://doi.org/10.1136/bmj.j311
Puar, T., Engels, M., van Herwaarden, A., Sweep, F., Hulsbergen-van de Kaa, C., Kamphuis-van Ulzen, K., Chortis, V., Arlt, W., Stikkelbroeck, N., Claahsen-van der Grinten, H., & Hermus, A. (2017). Bilateral testicular tumors resulting in recurrent Cushing's syndrome after bilateral adrenalectomy. Journal of Clinical Endocrinology and Metabolism, 102(2), 339-344. https://doi.org/10.1210/jc.2016-2702
Tamblyn, J., Susarla, R., Jenkinson, C., Jeffery, L., Ohizua, O., Chun, R., Chan, S. Y., Kilby, M., & Hewison, M. (2017). Dysregulation of maternal and placental vitamin D metabolism in preeclampsia. Placenta, 50, 70-77. https://doi.org/10.1016/j.placenta.2016.12.019
Lavrentaki, A., Karavitaki, N., Paluzzi, A., & Wass, J. A. H. (2017). Epidemiology of Acromegaly: Review of population studies. Pituitary, 20(1), 4–9. https://doi.org/10.1007/s11102-016-0754-x
Dafoulas, G. E., Toulis, K., Mccorry, D., Kumarendran, B., Thomas, G. N., Willis, B. H., Gokhale, K., Gkoutos, G., Narendran, P., & Nirantharakumar, K. (2017). Type 1 diabetes mellitus and risk of incident epilepsy: a population-based, open-cohort study. Diabetologia, 60(2), 258-261. https://doi.org/10.1007/s00125-016-4142-x
Karamat, M. A., Raja, U. Y., Manley, S. E., Jones, A., Hanif, W., & Tahrani, A. A. (2017). Prevalence of undiagnosed type 2 diabetes in patients admitted with acute coronary syndrome: the utility of easily reproducible screening methods. BMC Endocrine Disorders, 17(3), [3]. https://doi.org/10.1186/s12902-017-0153-y
Amin, A., Ali, A., Altaf, QA., Piya, MK., Barnett, AH., Raymond, NT., & Tahrani, AA. (2017). Prevalence and associations of obstructive sleep apnea in South Asians and White Europeans with Type 2 diabetes: A cross-sectional study. The Journal of Clinical Sleep Medicine, 13(4). http://jcsm.aasm.org/ViewAbstract.aspx?pid=30993
Le Tissier, P., Campos, P., Lafont, C., Romano, N., Hodson, D., & Mollard, P. (2017). An updated view of hypothalamic–vascular–pituitary unit function and plasticity. Nature Reviews Endocrinology, 13, 257-267. https://doi.org/10.1038/nrendo.2016.193
Amin, A., Ali, A., Altaf, Q. A., Piya, M. K., Barnett, A. H., Raymond, N. T., & Tahrani, A. A. (2017). Prevalence and associations of obstructive sleep apnea in South Asians and White Europeans with type 2 diabetes: A cross-sectional study. The Journal of Clinical Sleep Medicine, 13(4), 583-589. https://doi.org/10.5664/jcsm.6548
Hornby, C., Mollan, S., Mitchell, J., Markey, K. A., Yangou, A., Wright, B., O'Reilly, M., & Sinclair, A. (2017). What do transgender patients teach us about Idiopathic Intracranial Hypertension? Neuro-Ophthalmology, 41(6), 326-329. https://doi.org/10.1080/01658107.2017.1316744
2016
Doig, C. L., & Lavery, G. G. (2016). PARP Inhibitors: Staying on Target? Cell Chemical Biology, 23(12), 1442-1443. https://doi.org/10.1016/j.chembiol.2016.12.003
Hornby, C., O'Reilly, M., Botfield, H., Markey, K., Kempegowda, P., Taylor, A., Hughes, B., Tomlinson, J., Arlt, W., & Sinclair, A. (2016). The Andro-metabolic signature of Idiopathic Intracranial Hypertension compared to Polycystic Ovary Syndrome and Simple Obesity. Journal of Neurology, Neurosurgery & Psychiatry, 87(12), e1.46-e1. https://doi.org/10.1136/jnnp-2016-315106.14
Hardy, R. S., Doig, C. L., Hussain, Z., O'Leary, M., Morgan, S. A., Pearson, M. J., Naylor, A., Jones, S., Filer, A., Stewart, P. M., Buckley, C. D., Lavery, G. G., Cooper, M. S., & Raza, K. (2016). 11β-hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. Journal of Pathology, 240(4), 472-483. https://doi.org/10.1002/path.4806
Bancos, I., Alahdab, F., Crowley, R., Chortis, V., Delivanis, D., Erickson, D., Natt, N., Terzolo, M., Arlt, W., Young Jr, W., & Murad, M. H. (2016). Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and Subclinical Cushing Syndrome: a systematic review and meta-analysis. European Journal of Endocrinology, 175(6), R283-R295. https://doi.org/10.1530/EJE-16-0465
Altaf, Q. A., Sadiqi, H., Piya, M. K., & Tahrani, A. A. (2016). Foot insensitivity is associated with renal function decline in patients with type 2 diabetes: a cohort study. BMC Endocrine Disorders, 16(1), 64. https://doi.org/10.1186/s12902-016-0147-1
Belli, A., Roper, L. S., Nightingale, P., Su, Z., & Sinclair, A. (2016). Disability from post-traumatic headache is compounded by PTSD. British Medical Journal. http://10.1136/jnnp-2016-315106.72
Jones, C., Mallappa, A., Reisch, N., Nikolaou, N., Krone, N., Hughes, B., O'Neil, D., Whitaker, M. J., Tomlinson, J., Storbeck, K-H., Merke, D. P., Ross, R., & Arlt, W. (2016). Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism, 102(6), 1797-1806. https://doi.org/10.1210/jc.2016-2855
Fleseriu, M., & Karavitaki, N. (2016). Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism, 101(11), 3888-3921. https://doi.org/10.1210/jc.2016-2118
Nieto, H., & Boelaert, K. (2016). Thyroid stimulating hormone in thyroid cancer: does it matter? Endocrine-related cancer, 23(11), [ERC-16-0328]. https://doi.org/10.1530/ERC-16-0328
Karavitaki, N. (2016). Audit on isolated pituitary stalk lesions/thickening in a tertiary hospital: Comprehensive guidelines needed. Poster session presented at Society for Endocrinology BES 2016, Brighton, United Kingdom. https://doi.org/10.1530/endoabs.44.P83
Essig, G. F., Porter, K., Schneider, D., Arpaia, D., Lindsey, S. C., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J. W., Meijer, J. A. A., Duntas, L. H., Sharma, N., Costante, G., Filetti, S., Sippel, R. S., Biondi, B., Topliss, D. J., Pacini, F., ... Kloos, R. T. (2016). Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study. Thyroid, 26(11), 1563-1572. https://doi.org/10.1089/thy.2016.0255
Arlt, W., & Clinical Committee, S. F. E. (2016). Society for Endocrinology Endocrine Emergency Guidance: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients. Endocrine Connections, 5(5), G1-G3. https://doi.org/10.1530/EC-16-0054
Boelaert, K. (2016). WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease. Endocrine-related cancer, 23(11), 9-13. https://doi.org/10.1530/ERC-16-0396
Sbardella, E., & Karavitaki, N. (2016). A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology. Journal of Clinical and Translational Endocrinology: Case Reports, [16-0038]. https://doi.org/10.1530/EDM-16-0038
O'reilly, M., Reulen, R., Gupta, S., Thompson, C., Dineen, R., Goulden, E., Bugg, G., Pearce, H., Toogood, A., Gittoes, N., Mitchell, R., Thompson, C., & Ayuk, J. (2016). ACTH and gonadotrophin deficiency predict mortality in patients treated for nonfunctioning pituitary adenoma (NFPA): long-term follow-up of 519 patients in two large European centres. Clinical Endocrinology, 85(5), 748–756. https://doi.org/10.1111/cen.13141
Walsh, J., Gittoes, N., & Selby, P. (2016). Emergency management of acute hypercalcaemia in adult patients. Endocrine Connections, 5, G9-G11. https://doi.org/10.1530/EC-16-0055
Johnston, N., Mitchell, R., Haythorne, E., Pessoa, M. P., Semplici, F., Ferrer, J., Piemonti, L., Marchetti, P., Bugliani, M., Bosco, D., Berishvili, E., Duncanson, P., Watkinson, M., Broichhagen, J., Trauner, D., Rutter, G., & Hodson, D. (2016). Beta cell hubs dictate pancreatic islet responses to glucose. Cell Metabolism, 24(3), 389-401. https://doi.org/10.1016/j.cmet.2016.06.020
Wakeling, E., Brioude, F., Lokulo-Sodipe, O., O'Connell, S., Salem, J., Bilek, J., Canton, A., Chrzanowska, K., Davies, J., Dias, R., Dubern, B., Elbracht, M., Giabicani, E., Grimberg, A., Groenskov, K., Hokken-Koelega, A., Jorge, A., Kagami, M., Linglart, A., ... Netchine, I. (2016). Diagnosis and management of Silver–Russell syndrome: first international consensus statement. Nature Reviews Endocrinology. https://doi.org/10.1038/nrendo.2016.138
Chun, R., Hernandez, I., Pereira, R., Swinkles, L., Huijs, T., Zhou, R., Liu, N., Shieh, A., Guemes, M., Mallya, S., Adams, J., & Hewison, M. (2016). Differential responses to vitamin D2 and vitamin d3 are associated with variations in free 25-hydroxyvitamin D. Endocrinology, 157(9), 3420-3430. https://doi.org/10.1210/en.2016-1139
Tampourlou, M., Karavitaki, N., Trifanescu, R., Paluzzi, A., & Ahmed, S. K. (2016). Therapy Of Endocrine Disease: Surgery In Microprolactinomas: Effectiveness And Risks Based On Contemporary Literature. European Journal of Endocrinology, 175(3), R89-96. https://doi.org/10.1530/EJE-16-0087
Larner, D., Morgan, S., Gathercole, L., Doig, C., Guest, P., Weston, C., Hazeldine, J., Tomlinson, J., Stewart, P., & Lavery, G. (2016). Male 11β-HSD1 knockout mice fed trans-fats and fructose are not protected from metabolic syndrome or non-alcoholic fatty liver disease. Endocrinology, 157(9). https://doi.org/10.1210/en.2016-1357
Chan, K. X., Mabbitt, P., Phua, S. Y., Mueller, J. W., Nisar, N., Gigolashvilli, T., Stroeher, E., Grassl, J., Arlt, W., Estavillo, G., Jackson, C., & Pogson, B. (2016). Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase. National Academy of Sciences. Proceedings, 113(31), E4567-E4576. https://doi.org/10.1073/pnas.1604936113
Fassnacht, M., Arlt, W., Bancos, I., Dralle, H., Newell-Price, J., Sahdev, A., Tabarin, A., Terzolo, M., Tsagarakis, S., & Dekkers, O. (2016). Management of adrenal incidentalomas - a European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. European Journal of Endocrinology, 175. https://doi.org/10.1530/EJE-16-0467
Dinnes, J., Bancos, I., Ferrante di Ruffano, L., Chortis, V., Davenport, C., Bayliss, S., Sahdev, A., Guest, P., Fassnacht, M., Deeks, J., & Arlt, W. (2016). Management of endocrine disease: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis . European Journal of Endocrinology, 175, R51-R64. https://doi.org/10.1530/EJE-16-0461
Bancos, I., Tamhane, S., Shah, M., Delivanis, D., Alahdab, F., Arlt, W., Fassnacht, M., & Murad, M. H. (2016). The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis. European Journal of Endocrinology, 175, R65-R80. https://doi.org/10.1530/EJE-16-0297
Sanderson, J., James, M. M-S., Stevens, J., Goka, E., Wong, R., Campbell, F., Selby, P., Gittoes, N., & Davis, S. (2016). Clinical effectiveness of bisphosphonates for the prevention of fragility fractures: a systematic review and network meta-analysis. Bone, 89, 52-58. https://doi.org/10.1016/j.bone.2016.05.013
Frank, J., Yushchenko, D., Hodson, D., Lipstein, N., Nagpal, J., Rutter, G., Rhee, J-S., Gottschalk, A., Brose, N., Schultz, C., & Trauner, D. (2016). Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology, 12, 755-762. https://doi.org/10.1038/nchembio.2141
Clayton, R., Jones, P., Reulen, R., Stewart, P., Hassan-Smith, Z., Ntali, G., Karavitaki, N., Dekkers, O., Pereira, A., Bolland, M., Holdaway, I., & Lindholm, J. (2016). Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study. The Lancet Diabetes and Endocrinology, 4(7), 569-576. https://doi.org/10.1016/S2213-8587(16)30005-5
El-Gamal, M., Semreen, M., Foster, P., & Potter, B. (2016). Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors. Bioorganic & Medicinal Chemistry, 24(12). https://doi.org/10.1016/j.bmc.2016.04.040
Idkowiak, J., Taylor, A. E., Subtil, S., O'neil, D. M., Vijzelaar, R., Dias, R. P., Amin, R., Barrett, T. G., Shackleton, C. H. L., Kirk, J. M. W., Moss, C., & Arlt, W. (2016). Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty. Journal of Clinical Endocrinology and Metabolism, 101(6), 2545-53. https://doi.org/10.1210/jc.2015-4101
Morgan, S., Hassan-Smith, Z., Doig, C., Sherlock, M., Stewart, P., & Lavery, G. (2016). Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism. Journal of Endocrinology, 229(3), 277-286. https://doi.org/10.1530/JOE-16-0011
Aojula, A., Botfield, H., McAllister, J. P., Gonzalez, A., Abdullah, O., Logan, A., & Sinclair, A. (2016). Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus. Fluids and barriers of the CNS, 13, [9]. https://doi.org/10.1186/s12987-016-0033-2
Ferreira, V., Marcelino, M., Piechnik, S., Marini, C., Karamitsos, T., Ntusi, N., Francis, J., Robson, M., Arnold, R., Mihai, R., Thomas, J., Herincs, M., Hassan-Smith, Z., Greiser, A., Arlt, W., Korbonits, M., Karavitaki, N., Grossman, A., Wass, J., & Neubauer, S. (2016). Pheochromocytoma Is characterized by catecholamine-mediated myocarditis, focal and diffuse myocardial fibrosis, and myocardial dysfunction. Journal of the American College of Cardiology, 67(20), 2364–2374. https://doi.org/10.1016/j.jacc.2016.03.543
Shipman, K., Stammers, J., Doyle, A., & Gittoes, N. (2016). Delivering a quality assured fracture liaison service in a UK teaching hospital – is it achievable? Osteoporosis International. https://doi.org/10.1007/s00198-016-3639-y
Rahman, H-U., Hofland, J., & Foster, P. (2016). In Touch with your Feminine Side: How Oestrogen Metabolism Impacts Prostate Cancer. Endocrine-related cancer. https://doi.org/10.1530/ERC-16-0118
Gathercole, L. L., Hazlehurst, J. M., Armstrong, M. J., Crowley, R., Boocock, S., O'Reilly, M. W., Round, M., Brown, R., Bolton, S., Cramb, R., Newsome, P., Semple, R. K., Paisey, R., Tomlinson, J. W., & Geberhiwot, T. (2016). Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. Liver International. https://doi.org/10.1111/liv.13163
Broichhagen, J., Johnston, N. R., Von Ohlen, Y., Meyer-berg, H., Jones, B. J., Bloom, S. R., Rutter, G. A., Trauner, D., & Hodson, D. J. (2016). Allosteric optical control of a class B G-protein-coupled receptor. Angewandte Chemie (International Edition) , 55(19), 5865–5868. https://doi.org/10.1002/anie.201600957
Kempegowda, P., O'Reilly, M. W., Hassan-Smith, Z., Storbeck, K-H., Taylor, A. E., & Arlt, W. (2016). Impaired DHEA sulfation defines androgen excess in women with polycystic ovarian syndrome (PCOS). Endocrine Abstracts. https://doi.org/10.1530/endoabs.41.GP184
Arlt, W., Torchen, L., Idkowiak, J., Fogel, N., O'Neil, D., Shackleton, C., & Dunaif, A. (2016). Evidence for Increased 5α-Reductase During Early Childhood in Daughters of Women with Polycystic Ovary Syndrome. Journal of Clinical Endocrinology and Metabolism, 101(5), 2069-2075. https://doi.org/10.1210/jc.2015-3926#sthash.9Wp6MrQ4.dpuf
Osterstock, G., Mitutsova, V., Barre, A., Granier, M., Fontanaud, P., Chazalon, M., Carmignac, D., Robinson, I., Low, M., Plesnila, N., Hodson, D., Mollard, P., & Mery, P-F. (2016). Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons. Scientific Reports, 6, [24394 ]. https://doi.org/10.1038/srep24394
Crowley, R. K., & Gittoes, N. J. (2016). Elevated PTH with normal serum calcium level: a structured approach. Clinical Endocrinology. https://doi.org/10.1111/cen.13056
Amin, A. M., Wharton, H., Clarke, M., Syed, A., Dodson, P., & Tahrani, A. A. (2016). The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: A retrospective cohort study. Surgery for Obesity and Related Diseases, 12(3), 606-612. https://doi.org/10.1016/j.soard.2015.08.508
Griffin, A., Parajes, S., Weger, M., Zaucker, A., Taylor, A. E., O'Neil, D. M., Müller, F., & Krone, N. (2016). Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish. Endocrinology, 157(3). https://doi.org/10.1210/en.2015-1480
Amin, A. M., Wharton, H., Clarke, M., Syed, A., Dodson, P., & Tahrani, A. A. (2016). The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: a retrospective cohort study. Surgery for Obesity and Related Diseases, 12(3), 606-612. https://doi.org/10.1016/j.soard.2015.08.508
Srikanth, P., Chun, R. F., Hewison, M., Adams, J. S., Bouillon, R., Vanderschueren, D., Lane, N., Cawthon, P. M., Dam, T., Barrett-Connor, E., Daniels, L. B., Shikany, J. M., Stefanick, M. L., Cauley, J. A., Orwoll, E. S., Nielson, C. M., & Osteoporotic Fractures in Men (MrOS) Study Research Group (2016). Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men. Osteoporosis International. https://doi.org/10.1007/s00198-016-3537-3
Bornstein, S. R., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G. D., Husebye, E. S., Merke, D. P., Murad, M. H., Stratakis, C. A., & Torpy, D. J. (2016). Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline. The Journal of clinical endocrinology and metabolism, 101(2), 364-89. https://doi.org/10.1210/jc.2015-1710
Juarez, M., McGettrick, H. M., Scheel-Toellner, D., Yeo, L., Spengler, J., de Paz, B., Hardy, R., Cooper, M., Raza, K., Buckley, C. D., & Filer, A. (2016). DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system. Arthritis Research & Therapy, 18(1), [14]. https://doi.org/10.1186/s13075-016-0915-3
Vitlic, A., Lord, J. M., Taylor, A. E., Arlt, W., Bartlett, D. B., Rossi, A., Arora-Duggal, N., Welham, A., Heald, M., Oliver, C., Carroll, D., & Phillips, A. C. (2016). Neutrophil function in young and old caregivers. British Journal of Health Psychology, 21(1), 173-189. https://doi.org/10.1111/bjhp.12156
Hazlehurst, J. M., Oprescu, A. I., Nikolaou, N., Di Guida, R., Grinbergs, A. E. K., Davies, N. P., Flintham, R. B., Armstrong, M. J., Taylor, A. E., Hughes, B. A., Yu, J., Hodson, L., Dunn, W. B., & Tomlinson, J. W. (2016). Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man. The Journal of clinical endocrinology and metabolism, 101(1), 103-113. https://doi.org/10.1210/jc.2015-2928
Doig, C. L., Battaglia, S., Khanim, F. L., Bunce, C. M., & Campbell, M. J. (2016). Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology, 155 ( Part A), 47-55. https://doi.org/10.1016/j.jsbmb.2015.09.037
Karavitaki, N. (2016). Craniopharyngiomas: Natural History and Clinical Presentation. In A. Lania, A. Spada, & G. Lasio (Eds.), Diagnosis and Management of Craniopharyngiomas Springer. https://doi.org/10.1007/978-3-319-22297-4_1
Sarkar, S., Hewison, M., Studzinski, G. P., Li, Y. C., & Kalia, V. (2016). Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer. Critical Reviews in Clinical Laboratory Sciences, 1-14. https://doi.org/10.3109/10408363.2015.1094443
Büttler, R. M., Martens, F., Fanelli, F., Pham, H. T., Kushnir, M. M., Janssen, M. J. W., Owen, L., Taylor, A. E., Soeborg, T., Blankenstein, M. A., & Heijboer, A. C. (2015). Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. Clinical Chemistry, 61(12), 1475-83. https://doi.org/10.1373/clinchem.2015.242859
Shaw, G. L., Whitaker, H., Corcoran, M., Dunning, M. J., Luxton, H., Kay, J., Massie, C. E., Miller, J. L., Lamb, A. D., Ross-Adams, H., Russell, R., Nelson, A. W., Eldridge, M. D., Lynch, A. G., Ramos-Montoya, A., Mills, I. G., Taylor, A. E., Arlt, W., Shah, N., ... Neal, D. E. (2015). The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer. European urology. https://doi.org/10.1016/j.eururo.2015.10.042
Woods, C. P., Argese, N., Chapman, M., Boot, C., Webster, R., Dabhi, V., Grossman, A. B., Toogood, A. A., Arlt, W., Stewart, P. M., Crowley, R. K., & Tomlinson, J. W. (2015). Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol. European Journal of Endocrinology, 173(5), 633-42. https://doi.org/10.1530/EJE-15-0608
Mooij, C. F., Parajes, S., Rose, I. T., Taylor, A. E., Bayraktaroglu, T., Wass, J. A. H., Connell, J. M. C., Ray, D. W., Arlt, W., & Krone, N. (2015). Characterization of the molecular genetic pathology in patients with 11β-hydroxylase deficiency. Clinical Endocrinology, 83(5), 629-635. https://doi.org/10.1111/cen.12834
Read, M., Fong, J., Imruetaicharoenchoke, W., Modasia, B., Lewy, G., Ryan, G., Sharma, N., Smith, V., Watkinson, J., Boelaert, K., & McCabe, C. (2015). Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression. Endocrine Abstracts, 38, [P149]. https://doi.org/10.1530/endoabs.38.P149
Read, M., Smith, J., Smith, V., Bosseboeuf, E., Wake, N., Watkinson, J., Wallis, Y., Maher, E., McCabe, C., & Woodward, E. (2015). Functional consequences of germline mutations in a novel non-RET medullary thyroid cancer susceptibility gene. Endocrine Abstracts, 38, [OC5.1]. https://doi.org/10.1530/endoabs.38.OC5.1
Sherlock, M., Behan, L. A., Hannon, M. J., Alonso, A. A., Thompson, C. J., Murray, R. D., Crabtree, N., Hughes, B. A., Arlt, W., Agha, A., Toogood, A. A., & Stewart, P. M. (2015). The modulation of corticosteroid metabolism by hydrocortisone therapy in patients with hypopituitarism increases tissue glucocorticoid exposure. European Journal of Endocrinology, 173(5), 583-93. https://doi.org/10.1530/EJE-15-0490
Dar, S., Tahrani, A. A., & Piya, M. K. (2015). The role of GLP-1 receptor agonists as weight loss agents in patients with and without type 2 diabetes. Practical Diabetes, 32(8), 297-300b. https://doi.org/10.1002/pdi.1978
Hodson, L., Banerjee, R., Rial, B., Arlt, W., Adiels, M., Boren, J., Marinou, K., Fisher, C., Mostad, I. L., Stratton, I. M., Barrett, P. H. R., Chan, D. C., Watts, G. F., Harnden, K., Karpe, F., & Fielding, B. A. (2015). Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women. Journal of the American Heart Association, 4(10), [e002258]. https://doi.org/10.1161/JAHA.115.002258
Kempegowda, P., O'Reilly, M. W., Crabtree, N. J., Taylor, A. E., Hughes, B. A., Tomlinson, J. W., & Arlt, W. (2015). Visceral fat drives 5[alpha]-reductase activity independent of BMI in women with polycystic ovarian syndrome. Endocrine Abstracts. https://doi.org/10.1530/endoabs.38.P356
O'Reilly, M., Kempegowda, P., Botfield, H., Ali, F., Taylor, A., Hughes, B., Tomlinson, J., Arlt, W., & Sinclair, A. (2015). Women with idiopathic intracranial hypertension have a distinct andro-metabolic signature compared to polycystic ovary syndrome and simple obesity. Endocrine Abstracts. https://doi.org/10.1530/endoabs.38.P193
Mueller, J. W., Gilligan, L. C., Idkowiak, J., Arlt, W., & Foster, P. A. (2015). The Regulation of Steroid Action by Sulfation and Desulfation. Endocrine Reviews, 36(5), 526-563. https://doi.org/10.1210/er.2015-1036
Stengel, C., Newman, S. P., Leese, M. P., Thomas, M. P., Potter, B. V. L., Reed, M. J., Purohit, A., & Foster, P. A. (2015). The in vitro and in vivo activity of the microtubule disruptor STX140 Is mediated by Hif-1 alpha and CAIX expression. Anticancer research, 35(10), 5249-5261. https://ar.iiarjournals.org/content/35/10/5249
Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., Davis, J., Cheer, K., Drake, W., Gunganah, K., Grossman, A., Gurnell, M., Powlson, A. S., Karavitaki, N., Huguet, I., ... Newell-Price, J. (2015). Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients. The Journal of clinical endocrinology and metabolism, 100(11), [jc20152616]. https://doi.org/10.1210/jc.2015-2616
Ahmed, S. F., Achermann, J. C., Arlt, W., Balen, A., Conway, G., Edwards, Z., Elford, S., Hughes, I. A., Izatt, L., Krone, N., Miles, H., O'Toole, S., Perry, L., Sanders, C., Simmonds, M., Watt, A., & Willis, D. (2015). Society for Endocrinology UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development (Revised 2015). Clinical Endocrinology. https://doi.org/10.1111/cen.12857
Taylor, A. E., Keevil, B., & Huhtaniemi, I. T. (2015). Mass spectrometry and immunoassay: how to measure steroid hormones today and tomorrow. European Journal of Endocrinology, 173(2), D1-12. https://doi.org/10.1530/EJE-15-0338
Capatina, C., Paluzzi, A., Mitchell, R., & Karavitaki, N. (2015). Diabetes insipidus after traumatic brain injury. Journal of Clinical Medicine, 4(7), 1448-62. https://doi.org/10.3390/jcm4071448
Hassan-Smith, Z. K., Morgan, S. A., Sherlock, M., Hughes, B., Taylor, A. E., Lavery, G. G., Tomlinson, J. W., & Stewart, P. M. (2015). Gender-specific differences in skeletal muscle 11β-HSD1 expression across healthy aging. The Journal of clinical endocrinology and metabolism, 100(7), 2673-2681. https://doi.org/10.1210/jc.2015-1516
Mooij, C. F., Parajes, S., Pijnenburg-Kleizen, K. J., Arlt, W., Krone, N., & Claahsen-van der Grinten, H. L. (2015). Influence of 17-Hydroxyprogesterone, Progesterone and Sex Steroids on Mineralocorticoid Receptor Transactivation in Congenital Adrenal Hyperplasia. Hormone research in paediatrics, 83(6), 414-421. https://doi.org/10.1159/000374112
Ho, S. C., Clayton, P., Vasudevan, P., Greening, J., Wardhaugh, B., Shaw, N., Kelnar, C., Kirk, J., & Högler, W. (2015). Recombinant Human Growth Hormone Therapy in Children with Chromosome 15q26 Deletion. Hormone Research in Paediatrics, 83(6), 424-430. https://doi.org/10.1159/000380949

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