CompARE: Phase III randomised controlled trial Comparing Alternative Regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer.

web_HPV_CompARE trial logoThe following trial documents are all password protected. 

Change of Staff

If there is a change of staff working on the trial please print off and complete the relevant registration form below. Please also ensure that the Signature and Delegation Log is updated. Return both documents to the CompARE Trial Office.

Trial Documents

Links to the current Protocol and Patient Documents are provided below. If there has been a recent amendment to the trial, please ensure you have R&D approval before using these documents.

Other documents (e.g. Case Report Forms, Serious Adverse Event Form, Guidelines, Patient Questionnaires, Amendments, etc.) can be found by clicking on the other menu items below. If you cannot find what you are looking for, please contact the CompARE Trial Office. 

Patient Documents



CRF & eRDC Guidelines:

Other Trial Documents


Below is a link to a document which lists all of the substantial protocol amendments which have been made for this trial. The folders below contain the relevant amended documentation and approval letters. Please ensure that you have R&D approval (if applicable) before using the latest versions of these documents.

  • Amendment 14, 14-Aug-2018 [opens new page]
  • Amendment 03, 07-Dec-2015 [opens new page]
  • Amendment 02, 12-Oct-2015 [opens new page]
  • Amendment 01, 15-Jul-2015 [opens new page]

Version Control Lists

The version numbers and dates of all documents used for the trial are captured on a Document Version Control List. Links to the Document Version Control Lists used in this trial are below, in reverse date order.

News and Events

Contact Details

Chief Investigator

Professor Hisham Mehanna, Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham. B15 2TT

Tel: +44 (0)121 414 6547

CompARE Trial Office

Senior Trial Coordinator: Isla Humphreys
Trial Coordinator: Annabell Allen 
Data Manager:

Trial Monitor: Alexandra Bryant 
Trial Management Team Leader: Claire Gaunt
Trial Statistician: Piers Gaunt

Cancer Research UK Clinical Trials Unit (CRCTU)
Institute of Cancer and Genomic Sciences
University of Birmingham
B15 2TT


Tel: +44 (0)121 414 5101

Trial Entry

Tel: +44 (0)121 414 5101  & +44 (0)121 414 9247  (9:00 am till 5:00 pm Monday to Friday)

Serious Adverse Event Reporting



University of Birmingham