Ependymoma: For Investigators

An international clinical program for the diagnosis and treatmentof children, adolescents and young adults with ependymoma.

Change of Staff

If there is a change of staff working on the trial please print off and complete the relevant registration form below. Please also ensure that the Signature and Delegation Log is updated. Return both documents to the Ependymoma II Trial Office.

Trial Documents

Links to the current protocol, Patient Information Sheet and Informed Consent Form are provided below. If there has been a recent amendment to the trial please ensure you have R&D approval before using these documents.

Other documents (e.g. Amendments, Case Report Form, Serious Adverse Event Form, Guidelines, GP Letter, Release of Medical Information Form etc) can be found by clicking on the other menu items below.

If you cannot find what you are looking for please email the Ependymoma II Trials Office.

Version Control Lists

The version numbers and dates of all documents used for the trial are captured on a Version Control Log. Links to the Version Control Lists used in this trial are below in reverse date order.


Below is a link to a document which lists all of the substantial protocol amendments which have been made for this trial. The folders below contain the relevant amended documentation and approval letters. Please ensure that you have R&D approval (if applicable) before using the latest versions of these documents.

Case Report Form



Other Trial Documents

Summary of Product Characteristics

News and Events

 Newsletters and Events will be updated throughout the length of the SIOP Ependymoma trial.

Contact Details

Chief Investigator

Professor Richard Grundy                                                                                 

Cancer Research UK Consultant in Paediatric Oncology

Cancer Research UK Clinical Trials Unit (CRCTU)
School of Cancer Sciences
University of Birmingham
B15 2TT

Tel: +44 (0) 121 414 7581

Email: richard.grundy@nottingham.ac.uk

SIOP Ependymoma Trial Office

Trial Coordinator:  Eileen Grimes
Trial Monitor: Saika Kauser  
Trial Management Team Leader:  Anna Lawson
Trial Statistician: Daniel Slade

Cancer Research UK Clinical Trials Unit (CRCTU)
School of Cancer Sciences
University of Birmingham
B15 2TT


Telephone: +44 (0) 121 414 7581 
Fax: +44 (0) 121 414 9520
Email: ependymoma@trials.bham.ac.uk

Trial Entry

Randomisation should be performed via RDE system at:


Serious Adverse Event Reporting

SAE's reported directly to Sponsor Safety Desk:

Fax: +33 9 81 40 42 80 or +33 4 78 78 27 15


Centre Leon Berard, 28 rue Laennec, 69008, Lyon, FRANCE

UK Coordinating Sponsor

University of Birmingham

CRCTU Home Page