Bubble Amendments

Substantial Amendments

The links below contain the relevant amended documentation and approval letters. Please ensure that you have R&D approval (if applicable) before using the latest versions of these documents.

  • Amendment 3.0
    • MHRA Approval letter [.pdf]
    • REC Approval letter [.pdf]
  • Amendment 2.0
    • Approval letter [.pdf]
  • Amendment 1.0
    • Approval letter [.pdf]
    • REC Cover letter [.pdf]
    • Protcol v2.0 [.pdf]
    • PIS v2.0 [.pdf]

Non-Substantial Amendments

As yet there have been no non-substantial amendments to the Bubble Trial