Below is a link to a document which lists all of the substantial protocol amendments which have been made for this trial. The folders below contain the relevant amended documentation and approval letters. Please ensure that you have R&D approval (if applicable) before using the latest versions of these documents.
- Summary of Amendments [.pdf]
- Amendment 19.0_17-May-2016 [.zip]
- Amendment 18.0_16-Dec-2015 [.zip]
- Amendment 17.0_18-Nov-2015 [.zip]
- Amendment 16.0_30-Jul-2016 [.zip]
- Amendment 15.0_29-Jan-2015 [.zip]
- Amendment 14.0_27-May-2014 [.zip]
- Amendment 13.0_11-Apr-2014 [.zip]
- Amendment 12.0_20-Nov-2013 [.zip]
- Amendment 11.0_02-Aug-2013 [.zip]
- Amendment 10.0_17-Jul-2013 [.zip]
- Amendment 9.0_21-May-2013 [.zip]
- Amendment 8.0_05-Apr-2013 [.zip]
- Amendment 7.0_11-Jan-2013 [.zip]
- Amendment 6.0_21-Aug-2012 [.zip]
- Amendment 5.0_28-Jun-2012 [.zip]
- Amendment 4.0_10-May-2012 [.zip]
- Amendment 2.0_27-Feb-2012 [.zip]
- Amendment 1.0_10-Feb-2012 [.zip]