Substantial Amendment 17 Back to 'For participating sites' All documents are pdf unless otherwise specified and require username and password login to access. SA17 MHRA Acknowledgement of amendment 25-Oct-2019 [pdf, 47 KB] SA17 MHRA Acceptance of Amendment 28-Nov-2019 [pdf, 47 KB] SA17 HRA Approval for the Amendment 06-Dec-2019 [pdf, 15 KB]