Substantial Amendment 20 Back to 'For participating sites' All documents are pdf unless otherwise specified and require username and password login to access. SA20 MHRA Acknowledgement of amendment 23-Oct-2020 [pdf, 46.1 KB] SA20 MHRA Acceptance of Amendment 26-Nov-2020 [pdf, 47.8 KB] SA20 HRA Approval for the Amendment 04-Dec-2020 [pdf, 120 KB]