We study the very early responses to Brain and Spinal trauma that reveal biomarkers for clinical outcomes, the mechanisms of acute neurodegeneration and long-term cognitive dysfunction, and develop novel neuroprotective, neuroregenerative and neurorepair technologies. A particular focus is concussion in professional football player.
Spinal cord injury (SCI) research includes discovery and translational research. Projects in the laboratory are focussed on understanding the underlying molecular mechanisms that prevent regeneration of axons after injury, the acute inflammatory response to injury, differences between SCI responses in mice versus rats, preventing SCI-induced oedema, inhibition of matrix metalloproteases and inhibiting DNA damage responses to promote functional recovery after injury.
Birmingham Spinal Cord Injury Research