Training materials

Publications

  • Brown, G., Kutner, A. and Marcinkowska E. (2016) Chapter 6: Vitamin D and leukaemia. In “Extraskeletal Effects of Vitamin D”. Ed: EP Liao. Pub: Springer, New York. In press. 
  • Zhang, Y., Garcia-Ibanez, L., Brown, G. and Toellner, K-M (2016). Detecting gene expression in lymphoid microenvironments by laser microdissection and quantitative RT-PCR. In “Germinal Centers: Methods and Protocols”. Ed: D Caldo. Pub: Springer, New York. In press. 
  • doi: 10.1016/j.imlet.2016.07.010 Ribeirio, A., Ritter, T., Griffin, M. and Ceredig, R. (2016) Development of a flow cytometry-based potency assay for measuring the in vitro immunomodulatory properties of Mesenchymal Stromal Cells. Immunology Letters. 177: 38–46
  • doi: 10.3390/ijms17071068 Nachliely, M., Sharony, E., Bolla, N. R., Kutner, A. and Danilenko, M. (2016) Prodifferentiation activity of novel vitamin D2 analogs PRI-1916 and PRI-1917 and their combinations with a plant polyphenol in acute myeloid leukemia cells. International Journal of Molecular Sciences. 17(7): 1068.
  • doi: 10.1080/13543776.2016.1205586 Marchwicka, A., Cunningham, A., Marcinkowska, E. and Brown, G. (2016) Therapeutic use of selective synthetic ligands for retinoic acid receptors: a patent review. Expert Opinion on Therapeutic Patents. [Epub ahead of print].
  • doi: 10.1016/j.intimp.2016.05.009 Gill, S. K, Islamb, N., Shaw, I., Ribeiro, A., Bradley, B., O’. Brien, T., Kilcoynea, M., Ceredig, R. and Joshi, L. (2016) Immunomodulatory effects of natural polysaccharides assessed in human whole blood culture and THP-1 cells show greater sensitivity of whole blood culture. International Immunopharmacology.
  • doi: 10.3390/ijms17050729 Marcinkowska, E., Wallace, G. R. and Brown, G. (2016) The use of 1α,25-dihydroxyvitamin D3 as an anticancer agent. International Journal of Molecular Sciences. 17(5): 729.
  • doi: 10.1007/s00005-016-0411-0 Brown, G., Marchwicka, A., Cunningham, A., Toellner, K-M. and Marcinkowska, E. (2016) Antagonizing retinoic acid receptors increases myeloid cell production by cultured human hematopoietic stem cells. Archivum Immunologiae et Therapiae Experimentalis. [Epub ahead of print].
  • doi: 10.1111/imr.12396 Zhang, Y., Garcia-Ibanez, L. and Toellner, K-M. (2016) Regulation of germinal center B-cell differentiation. Immunological Reviews. 270: 8-19.
  • doi: 10.1186/s13578-016-0075-9 Marchwicka, A., Corcoran, A., Berkowska, K. and Marcinkowska, E. (2016) Restored expression of vitamin D receptor and sensitivity to 1,25‑dihydroxyvitamin D3 in response to disrupted fusion FOP2–FGFR1 gene in acute myeloid leukemia cells. Cell & Bioscience. 6:7.
  • Sugrue, T., Calvo-Asensio, I and Ceredig R. (2016) The radio-resistance of mesenchymal stromal cells and their potential role in the management of radiation injury. In “The Biology and Therapeutic Application of Mesenchymal Cells”. Ed: K Atkinson. Pub: Wiley Blackwell Publishers, Hoboken, New Jersey, USA. In press.
  • doi:10.1016/j.jsbmb.2016.03.013 Marchwicka, A.,  Cebrat, M., Łaszkiewicz, A., Śnieżewski, Ł., Brown, Marcinkowska, E. (2016) Regulation of vitamin D receptor expression by retinoic acid receptor alpha in acute myeloid leukemia cells. Journal of Steroid Biochemistry & Molecular Biology. [Epub ahead of print].
  • doi:10.3390/ijms17020091 Corcoran, A., Nadkarni, S., Yasuda K., Sakaki T., Brown G., Kutner, A. and Marcinkowska, E. (2016) Biological evaluation of double point modified analogues of 1,25-dihydroxyvitamin D2 as potential anti-leukemic agents. International Journal of Molecular Sciences. [Epub ahead of print].
  • doi:10.3390/ijms17010076 Piotrowska, A., Wierzbicka, J., Nadkarni, S., Brown, G., Kutner, A and Zmijewski, M. (2015) Antiproliferative activity of double point modified analogs of 1,25-dihydroxyvitamin D2 against human malignant melanoma cell lines. International Journal of Molecular Sciences. [Epub ahead of print]. 
  • doi:10.1016/j.jsbmb.2015.09.014 Nachliely, M., Sharony, E., Kutner, A. and Danilenko, M. (2015) Novel analogs of 1,25-dihydroxyvitamin D2 combined with a plant polyphenol as highly efficient inducers of differentiation in human acute myeloid leukemia cells. Journal of Steroid Biochemistry & Molecular Biology. [Epub ahead of print]. 
  • doi:10.1016/j.jsbmb.2015.10.015 Kozielewicz, P., Grafton, G., Kutner, A., Curnow S. J., Gordon, J. and Barnes, N. M. (2015) Novel vitamin D analogues; cytotoxic and anti-proliferative activity against a diffuse large B-cell lymphoma cell line and B-cells from healthy donors. Journal of Steroid Biochemistry & Molecular Biology. [Epub ahead of print]. 

  • doi:10.1089/scd.2014.0235 Wai, H.A., Kawakami, K., Wada, H., Muller, F., Vernallis, A. B., Brown, G. and Johnson, W. E. B. (2015) The development and growth of tissues derived from neural crest and primitive mesoderm is dependent on the ligation status of retinoic acid receptor gamma: evidence that retinoic receptor gamma functions to maintain stem/progenitors in the absence of retinoic acid. Stem Cells and Development. 24: 507-519 [Featured article]. 
  • doi:10.1016/j.jsbmb.2015.08.022 Nadkarni, S., Chodynski, M., Krajewski, K., Cmoch, P., Marcinkowska, E., Brown, G. and Kutner, A. (2015) Convergent synthesis of double point modified analogs of 1α,25-dihydroxyvitamin D2 for biological evaluation. Journal of Steroid Biochemistry and Molecular Biology. [Epub ahead of print]. 
  • doi:10.1016/j.jsbmb.2015.09.033 Corcoran, A., Bermudez, M. A., Seoane, S., Perez-Fernandez, R., Krupa, M., Pietraszek, A., Chodyński, M., Kutner, A., Brown, G. and Marcinkowska, E. (2015) Biological evaluation of new vitamin D2 analogues. Journal of Steroid Biochemistry and Molecular Biology. [Epub ahead of print]. 
  • doi:10.1016/j.jsbmb.2015.08.025 Bolla, N. R., Corcoran, A., Yasuda, K., Chodyński, M., Krajewski, K., Cmoch, P., Marcinkowska, E., Brown, G., Sakaki, T. and Kutner, A. (2015)  Synthesis and evaluation of geometric analogs of 1α,25-dihydroxyvitamin D2 as potential therapeutics. Journal of Steroid Biochemistry & Molecular Biology. [Epub ahead of print]. 
  • doi:10.1186/s13287-015-0139-5 Baustian, C., Hanley, S. and Ceredig, R. (2015) Isolation, selection and culture methods to enhance clonogenicity of mouse bone marrow derived mesenchymal stromal cell precursors. Stem Cell Research & Therapy. [Epub ahead of print]. 
  • doi:10.3109/10408363.2015.1021412 Brown, G., Mooney, C. J., Alberti-Servera, L., Von Muenchow, L., Toellner, K-M., Ceredig, R. and Rolink, A. (2015) Versatility of stem and progenitor cells and the instructive actions of cytokines on haematopoiesis. Critical Reviews in Clinical Laboratory Sciences. 52: 168-179. 
  • doi:10.18632/oncotarget.6145 Brown, G. and Sanchez-Garcia, I. (2015) Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells? Oncotarget. 6: 43326-43341. 
  • doi:10.1002/eji.201444681 Gehre, N., Nusser, A., Von Muenchow, L., Tussiwand, R., Engdahl, C., Capoferri, G., Bosco, N., Ceredig, R. and Rolink, A. G. (2015) A stromal cell-free culture system generates mouse pro-T cells that can reconstitute T-cell compartments in vivo. European Journal of Immunology. 45: 932-942. 
  • doi:10.2174/1381612821666141205125113 Nadkarni, S., Chodyński, M., Corcoran, A., Marcinkowska, E., Brown, G. and Kutner, A. (2014) Double point modified analogs of vitamin D as potent activators of vitamin D receptor. Current Pharmaceutical Design. 21: 1241-1763. 
  • Hughes, P. J., Kutner, A. and Brown, G. (2014) Understanding the physiology, pharmacology and therapeutic uses of vitamin D. Journal of Aesthetic Nursing. 3: 276-285. 
  • doi:10.1016/j.imlet.2014.01.011 Von Muenchow, L., Engdahl, C., Karjalainen, K. and Rolink, A. G. (2014) The selection of mature B cells is critically dependent on the expression level of the co-receptor CD19. Immunology Letters. 160: 113-119. 
  • doi:10.1517/13543776.2014.898061 Bolla, N. R., Marcinkowska, E., Brown, G. and Kutner, A. (2014) Retiferols – synthesis and biological activity of a conceptually novel class of vitamin D analogs. Expert Opinion on Therapeutic Patents. 24: 633-646. 
  • Hughes, P. J., Kutner, A. and Brown, G., (2013) Shedding light on the physiology and pharmacology of vitamin D. Nurse Prescribing. 11: 344-352. 

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